Ethyl isonicotinate is a compound commonly used in the pharmaceutical industry for its antimicrobial and anti-inflammatory properties. In everyday life, this compound may be found in various topical creams and ointments used to treat skin conditions such as eczema, psoriasis, and acne. Its ability to reduce inflammation and fight off harmful microorganisms makes it a valuable ingredient in skincare products designed to promote healthy skin. Additionally, ethyl isonicotinate has potential applications in the development of new medications for various medical conditions, highlighting its importance in both healthcare and research.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Ethyl isonicotinate, also known as isonicotinic acid ethyl ester, has various commercial and industrial applications. It is commonly used as a precursor in the synthesis of pharmaceuticals and agrochemicals. Additionally, it is utilized in the production of dyes, pigments, and other specialty chemicals due to its ability to undergo various chemical reactions.
In terms of drug and medication applications, ethyl isonicotinate is used as an intermediate in the manufacturing of anti-tuberculosis drugs such as isoniazid. It plays a significant role in the treatment of tuberculosis by inhibiting the growth of the causative bacteria. Furthermore, ethyl isonicotinate has potential applications in the development of other pharmaceutical products targeting various diseases and conditions due to its chemical properties and reactivity.
⚗️ Chemical & Physical Properties
Ethyl isonicotinate is a colorless liquid with a sweet odor. It is commonly used as a synthetic flavoring agent in food products.
The molar mass of ethyl isonicotinate is approximately 167.19 g/mol, with a density of around 1.072 g/cm³. This places it in the same range as common food items such as sugar (molar mass of 342.3 g/mol, density of 1.587 g/cm³) and salt (molar mass of 58.44 g/mol, density of 2.16 g/cm³).
Ethyl isonicotinate has a melting point of around -20°C and a boiling point of approximately 235°C. This differs from common food items like butter (melting point around 32-35°C, boiling point around 177°C) and water (melting point at 0°C, boiling point at 100°C).
Ethyl isonicotinate is slightly soluble in water and has a low viscosity. This contrasts with common food items like sugar (high solubility in water) and honey (high viscosity).
🏭 Production & Procurement
Ethyl isonicotinate, a chemical compound with the molecular formula C9H9NO2, is primarily produced through the esterification reaction between isonicotinic acid and ethanol. This process involves the conversion of the carboxylic acid group of isonicotinic acid into an ester using ethanol as the alcohol component. The reaction is typically carried out under specific conditions including controlled temperatures and acid catalysts to facilitate the formation of Ethyl isonicotinate.
For procurement and transportation, Ethyl isonicotinate can be obtained from chemical suppliers or manufacturers who specialize in the production of pharmaceutical intermediates. It is commonly available in different purities and quantities, depending on the intended use. Ethyl isonicotinate is typically packaged in appropriate containers to ensure its safe transportation, and it may be shipped via various modes of transportation such as road, rail, air, or sea freight.
In terms of storage and handling, Ethyl isonicotinate should be stored in a cool, dry place away from direct sunlight and incompatible substances. Proper labeling and documentation are essential for the safe handling and identification of Ethyl isonicotinate during procurement and transportation. Additionally, adherence to regulations and guidelines regarding the storage and transportation of chemicals is crucial to ensure the integrity and safety of Ethyl isonicotinate throughout its journey from production to final destination.
⚠️ Safety Considerations
Safety considerations for Ethyl isonicotinate include the potential for skin and eye irritation upon contact. It is recommended to wear suitable protective clothing, gloves, and eye/face protection when handling this substance. In case of ingestion, seek medical advice immediately and show the container or label.
As with any chemical substance, Ethyl isonicotinate carries certain hazard statements that should be taken into consideration. These statements include “Causes skin irritation” and “Causes serious eye irritation.” It is important to be aware of these hazards and take appropriate precautions to minimize any potential risks associated with handling this compound.
Precautionary statements for Ethyl isonicotinate include recommendations to wash thoroughly after handling, avoid breathing dust/fume/gas/mist/vapors/spray, and wear protective gloves/protective clothing/eye protection/face protection. It is also advised to keep the substance in a well-ventilated area and store it in a tightly closed container. Additionally, it is important to dispose of any unused or expired Ethyl isonicotinate according to local regulations.
🔬 Potential Research Directions
Ethyl isonicotinate is a compound that has shown potential as a building block in the synthesis of pharmaceuticals and other biologically active molecules. Its unique chemical structure makes it an interesting target for further investigation in the field of organic chemistry.
One potential research direction for ethyl isonicotinate is the development of new synthetic methodologies that utilize this compound as a key intermediate. By exploring the reactivity of ethyl isonicotinate with various functional groups, researchers may discover novel ways to create complex molecules more efficiently.
Another area of interest for ethyl isonicotinate research is its potential pharmacological activity. Studies have shown that this compound may have anti-inflammatory and antioxidant properties, suggesting that it could be a valuable lead compound for the development of new therapeutics. Further investigation into its biological activity could uncover new applications in the field of medicine.
🧪 Related Compounds
One similar compound to Ethyl isonicotinate with a comparable molecular structure is Methyl isonicotinate. This compound also features a pyridine ring with a carboxyl group, but differs in the side chain where an ethyl group is replaced with a methyl group. Despite this substitution, Methyl isonicotinate shares similarity in its chemical properties with Ethyl isonicotinate, such as its potential pharmaceutical applications and reactivity in organic synthesis.
Another analogous compound to Ethyl isonicotinate is Butyl isonicotinate. This compound contains the same pyridine ring and carboxyl group as Ethyl isonicotinate, but possesses a larger alkyl side chain. The presence of a longer butyl group may result in differences in solubility, volatility, and reactivity compared to Ethyl isonicotinate. However, both compounds exhibit similarities in structure that make them attractive candidates for studies in medicinal chemistry and related fields.
A third related compound to Ethyl isonicotinate is Isopropyl isonicotinate. This compound shares the pyridine ring and carboxyl group found in Ethyl isonicotinate, but contains a distinct isopropyl side chain. The differences in the side chain may influence the compound’s physical and chemical properties, such as melting point, boiling point, and polarity. Despite these variations, Isopropyl isonicotinate maintains structural similarities with Ethyl isonicotinate that may be relevant in various applications within the pharmaceutical and chemical industries.
