4-Chloro-2-methylaniline, a chemical compound commonly used in the manufacturing of dyes and pigments, plays a significant role in everyday life despite its relatively obscure nature. This compound is crucial in producing vibrant colors in textiles, cosmetics, and various consumer products. Additionally, 4-Chloro-2-methylaniline is utilized in the pharmaceutical industry for the synthesis of certain medications. Therefore, while not directly encountered by most individuals, 4-Chloro-2-methylaniline contributes to the aesthetics and functionality of numerous products that are integral to daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Chloro-2-methylaniline, also known as PCA, has several commercial and industrial applications. It is commonly used as a building block in the synthesis of various organic compounds, such as dyes, pharmaceuticals, and agrochemicals. PCA is also utilized in the manufacturing of rubber chemicals and antioxidants for plastics.
In the realm of drug and medication applications, 4-Chloro-2-methylaniline plays a significant role as an intermediate in the production of pharmaceutical ingredients. It is often employed in the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents. Additionally, PCA is utilized in the manufacturing of pesticides and herbicides for agricultural purposes.
Overall, 4-Chloro-2-methylaniline serves as a versatile chemical compound with diverse commercial, industrial, and pharmaceutical applications. Its unique properties and reactivity make it a valuable ingredient in the synthesis of various products across different sectors.
⚗️ Chemical & Physical Properties
4-Chloro-2-methylaniline is a white crystalline solid with a faint aromatic odor. It is often used in the synthesis of various organic compounds.
The molar mass of 4-Chloro-2-methylaniline is approximately 141.6 g/mol, and its density is about 1.29 g/cm^3. Compared to common food items like table salt (molar mass of 58.44 g/mol) and water (density of 1 g/cm^3), 4-Chloro-2-methylaniline has a higher molar mass and density.
The melting point of 4-Chloro-2-methylaniline is around 38-40°C, while its boiling point is approximately 253-255°C. In comparison, common food items like butter (melting point around 32-35°C) and sugar (boiling point around 160-186°C) have lower melting and boiling points.
4-Chloro-2-methylaniline has limited solubility in water, but it is more soluble in organic solvents. It has a low viscosity, making it easy to handle in laboratory settings. Compared to common food items like sugar (highly soluble in water) and honey (high viscosity), 4-Chloro-2-methylaniline differs in its solubility and viscosity properties.
🏭 Production & Procurement
4-Chloro-2-methylaniline, a chemical compound used in various industries, is primarily produced through a multistep synthesis process involving the alkylation of 4-chloroaniline with methyl chloride. This reaction, typically carried out in the presence of a catalyst, results in the formation of 4-Chloro-2-methylaniline as the main product. Subsequent purification steps may be necessary to achieve the desired level of purity.
Following the production of 4-Chloro-2-methylaniline, the compound can be procured from chemical suppliers specializing in the distribution of fine chemicals and intermediates. The procurement process typically involves placing an order with a supplier, specifying the required quantity and purity level of the compound. Once the order is confirmed, the compound is packaged according to industry standards and transported to the customer’s location using approved shipping methods.
In terms of transportation, 4-Chloro-2-methylaniline is classified as a hazardous material due to its potential health and environmental hazards. Consequently, the compound must be handled and transported in compliance with applicable regulations, such as those outlined by the Department of Transportation (DOT) in the United States. Proper labeling and documentation are essential to ensure safe and secure transit of 4-Chloro-2-methylaniline from the supplier to the end user.
⚠️ Safety Considerations
Safety considerations for 4-Chloro-2-methylaniline include the potential for skin irritation and sensitization upon contact. This compound should be handled with caution, as it may cause severe eye irritation. Inhalation of the vapors or dust of 4-Chloro-2-methylaniline should be avoided, as it may cause respiratory irritation or other adverse effects. Proper personal protective equipment, such as gloves, goggles, and a lab coat, should be worn when working with this compound to minimize the risk of exposure.
Hazard statements for 4-Chloro-2-methylaniline include: “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These hazard statements indicate the potential risks associated with exposure to this compound. Individuals working with 4-Chloro-2-methylaniline should be aware of these hazards and take appropriate precautions to protect themselves from harm.
Precautionary statements for 4-Chloro-2-methylaniline include: “Avoid breathing dust/fume/gas/mist/vapors/spray,” “Wear protective gloves/protective clothing/eye protection/face protection,” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” These precautionary statements provide guidance on how to safely handle 4-Chloro-2-methylaniline and what to do in case of exposure. Following these precautions can help to minimize the risk of harm when working with this compound.
🔬 Potential Research Directions
Research on 4-Chloro-2-methylaniline may focus on its synthesis and purification methods to improve efficiency and yield. Further investigations could delve into the compound’s chemical properties, such as its reactivity with other substances, stability under different conditions, and potential applications in organic synthesis.
Exploring the toxicological effects of 4-Chloro-2-methylaniline on living organisms could be another avenue of research, shedding light on its potential hazards and safe handling guidelines. Studies analyzing the compound’s environmental fate and degradation pathways could provide valuable insight into its impact on ecosystems and contribute to the development of effective remediation strategies.
Furthermore, investigations on the potential medicinal properties of 4-Chloro-2-methylaniline could uncover its pharmacological activities and therapeutic applications. Research in this area may involve evaluating its bioactivity, toxicity profiles, and interactions with biological systems to assess its potential as a drug candidate or lead compound for pharmaceutical development.
Lastly, studies focusing on the industrial applications of 4-Chloro-2-methylaniline could investigate its utility as a precursor for the synthesis of dyes, pigments, or other specialty chemicals. Research in this area may involve optimizing reaction conditions, exploring new synthetic routes, and assessing the compound’s performance in industrial processes to enhance its commercial value and versatility.
🧪 Related Compounds
One similar compound to 4-Chloro-2-methylaniline is 2-Chloro-4-methylaniline, which has a molecular structure where the positions of the chlorine and methyl groups are reversed. This compound also belongs to the family of aniline derivatives, sharing a similar aromatic ring structure with a chlorine and methyl group attached to it.
Another similar compound is 4-Chloro-2-ethylaniline, which has a molecular structure where the methyl group in 4-Chloro-2-methylaniline is replaced with an ethyl group. This compound also falls under the category of aniline derivatives, possessing a chlorine and ethyl group attached to the aromatic ring.
A third related compound is 4-Chloro-2-propylaniline, in which the methyl group in 4-Chloro-2-methylaniline is replaced with a propyl group. This compound also exhibits similarities in structure and properties due to the presence of the chlorine and propyl groups attached to the aromatic ring.
