Salicyl alcohol

Salicyl alcohol, also known as ortho-hydroxybenzyl alcohol, holds significant relevance in everyday life due to its various applications in industries such as pharmaceuticals, cosmetics, and food preservation. This compound is commonly used in the production of medications for pain relief, skin care products, and as a preservative in food items. The anti-inflammatory and antimicrobial properties of salicyl alcohol make it a versatile ingredient in daily consumer goods, contributing to its relevance in modern society.

Table of Contents:

• 💡  Commercial Applications
• ⚗️  Chemical & Physical Properties
• 🏭  Production & Procurement
• ⚠️  Safety Considerations
• 🔬  Potential Research Directions
• 🧪  Related Compounds

💡 Commercial Applications

Salicyl alcohol, also known as 2-Hydroxybenzyl alcohol, has various commercial and industrial applications due to its properties. It is commonly used as a fragrance ingredient in perfumes, soaps, and personal care products. Additionally, it is also utilized as a flavoring agent in food and beverages, imparting a pleasant aroma and taste.

In the pharmaceutical industry, Salicyl alcohol is primarily utilized in the synthesis of various drugs and medications. It serves as a key intermediate in the production of aspirin, a widely used pain reliever and anti-inflammatory drug. Furthermore, it is also used in the manufacture of other pharmaceutical compounds such as salicylates and dyes.

Due to its antiseptic properties, Salicyl alcohol finds applications in the cosmetic industry as an ingredient in skincare products. It is known for its ability to exfoliate the skin, unclog pores, and reduce acne. Salicyl alcohol is often incorporated into creams, lotions, and cleansers to promote clearer and healthier skin.

⚗️ Chemical & Physical Properties

Salicyl alcohol is a colorless solid with a slightly sweet, aromatic odor. It is soluble in alcohol and ether, but has limited solubility in water.

With a molar mass of approximately 122.12 g/mol and a density of about 1.169 g/cm³, Salicyl alcohol is heavier than common household items such as water (molar mass of 18.015 g/mol and density of 1 g/cm³) and ethanol (molar mass of 46.07 g/mol and density of 0.789 g/cm³).

Salicyl alcohol has a melting point of around 87.5°C and a boiling point of approximately 243.5°C. Compared to common household items like sugar (melting point of 186°C) and water (boiling point of 100°C), Salicyl alcohol has a lower melting point and a higher boiling point.

Salicyl alcohol is sparingly soluble in water, but dissolves readily in alcohol and ether. Its viscosity is moderate, making it slightly more viscous than water but less so than honey.

🏭 Production & Procurement

Salicyl alcohol, also known as o-hydroxybenzyl alcohol, is typically produced through the Kolbe-Schmitt reaction. This reaction involves the treatment of phenol with sodium hydroxide and carbon dioxide to form sodium salicylate, which is then acidified to yield the desired salicyl alcohol product. The process typically requires precise control of reaction conditions to ensure high yield and purity.

Salicyl alcohol can be procured from chemical suppliers or produced in-house by chemical manufacturers. It is commonly available in both liquid and solid forms, depending on the intended application. The compound can be transported in sealed containers to prevent contamination or degradation during transit. Proper labeling and handling procedures should be followed to ensure safe transport and storage of Salicyl alcohol.

Given its various applications in pharmaceuticals, fragrances, and other industries, Salicyl alcohol is often in demand for commercial use. Chemical distributors and manufacturers play a key role in supplying this compound to customers worldwide. Quality control measures are crucial in the procurement process to ensure that the product meets the required specifications and standards. Overall, the production and procurement of Salicyl alcohol involve careful synthesis, handling, and transportation practices to ensure optimal results.

⚠️ Safety Considerations

Safety Considerations for Salicyl Alcohol:

When handling Salicyl alcohol, it is essential to be aware of its potential hazards and take necessary precautions. The substance should be stored in a cool, dry place away from direct sunlight and sources of heat. It is also crucial to avoid contact with skin, eyes, and clothing, as it can cause irritation or burns. Proper ventilation should be ensured when using Salicyl alcohol to prevent inhalation of vapors.

Pharmacology of Salicyl Alcohol:

Salicyl alcohol, also known as saligenin, is a chemical compound with both analgesic and antipyretic properties. It is a derivative of salicylic acid and shares similar pharmacological effects with aspirin. Salicyl alcohol has been used in topical applications for its anti-inflammatory and pain-relieving properties.

Hazard Statements for Salicyl Alcohol:

Salicyl alcohol is classified as a hazardous substance due to its potential health risks. It may cause skin and eye irritation upon contact and can be harmful if inhaled. Prolonged or repeated exposure to Salicyl alcohol may lead to sensitization or allergic reactions. In case of accidental ingestion, medical attention should be sought immediately.

Precautionary Statements for Salicyl Alcohol:

When handling Salicyl alcohol, it is recommended to wear appropriate personal protective equipment, such as gloves and safety goggles. Avoid breathing in vapors or dust, and wash hands thoroughly after handling the substance. In case of spills, clean up promptly using absorbent materials and dispose of properly. Keep Salicyl alcohol away from children and pets to prevent accidental exposure.

🔬 Potential Research Directions

Potential research directions for salicyl alcohol focus on exploring its antimicrobial properties and potential pharmaceutical applications. Studies could investigate its ability to inhibit the growth of various bacteria and fungi, as well as its potential use in topical treatments for skin infections.

Further research could also examine the antioxidant capabilities of salicyl alcohol and its potential role in reducing oxidative stress in the body. This could open up avenues for exploring its use in the development of antioxidant supplements or skincare products aimed at promoting skin health and preventing cell damage.

Additionally, research could delve into the potential anti-inflammatory properties of salicyl alcohol and its impact on inflammatory pathways in the body. This could lead to a better understanding of how salicyl alcohol may be used to alleviate symptoms of inflammatory conditions and potentially inform the development of new anti-inflammatory drugs.

🧪 Related Compounds

One similar compound to Salicyl alcohol based upon molecular structure is Benzyl alcohol. Benzyl alcohol has a benzene ring attached to a hydroxyl group, similar to Salicyl alcohol. It is commonly used as a solvent in various industries and also as a preservative in certain medications and personal care products.

Another compound with a similar structure to Salicyl alcohol is Phenol. Phenol consists of a benzene ring with a hydroxyl group attached, just like Salicyl alcohol. It is known for its antiseptic properties and is used in various pharmaceutical, chemical, and industrial applications.

A compound that bears resemblance to Salicyl alcohol in terms of molecular structure is Ethyl alcohol, also known as ethanol. While not a phenol derivative like Salicyl alcohol, Ethyl alcohol contains a hydroxyl group attached to a carbon atom. Ethyl alcohol is a common alcohol used in beverages, pharmaceuticals, and cosmetics due to its solubility and disinfectant properties.