2-Bromoacetophenone, a chemical compound used in various industries such as pharmaceuticals, cosmetics, and as a building block in organic synthesis, may not seem directly relevant to everyday life for most individuals. However, its presence in the production of medicines, fragrances, and other consumer products highlights its importance in maintaining the functionality of our modern society. Additionally, the study and utilization of 2-Bromoacetophenone in research and development contribute to advancements in technology and innovation that eventually benefit the general population.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Bromoacetophenone, a chemical compound derived from acetophenone, has found various commercial and industrial applications. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and fragrances due to its versatile nature and reactivity. Additionally, 2-Bromoacetophenone is utilized in the manufacturing of dyes and polymers, showcasing its significance in the chemical industry.
In terms of drug and medication applications, 2-Bromoacetophenone has been studied for its potential use as an intermediate in the production of pharmaceuticals. It plays a crucial role in the synthesis of various active pharmaceutical ingredients, aiding in the development of novel drugs for a wide range of medical conditions. Furthermore, 2-Bromoacetophenone’s chemical properties make it a valuable component in the creation of drugs with enhanced therapeutic effects and improved bioavailability.
Overall, the commercial and industrial applications of 2-Bromoacetophenone highlight its importance in the chemical sector and pharmaceutical industry. With its diverse uses and contributions to various fields, this compound continues to be a valuable resource for researchers and manufacturers seeking to innovate and develop new products.
⚗️ Chemical & Physical Properties
2-Bromoacetophenone is a white to off-white crystalline solid with a strong, pungent odor. The compound is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds due to its versatile chemical properties.
With a molar mass of 205.06 g/mol and a density of 1.429 g/cm³, 2-Bromoacetophenone is heavier and denser than common food items such as sugar and salt. This high molar mass and density contribute to its relatively low volatility and high stability in various chemical reactions.
2-Bromoacetophenone has a melting point of approximately 47-48°C and a boiling point of around 291-292°C. In comparison to common food items like butter and chocolate, which have lower melting and boiling points, 2-Bromoacetophenone exhibits a higher thermal stability under typical cooking conditions.
The compound is sparingly soluble in water but more soluble in organic solvents. It has a relatively low viscosity compared to common food items like honey and molasses. This property makes it easier to handle and manipulate in laboratory settings, where precise measurements and controlled reactions are necessary.
🏭 Production & Procurement
2-Bromoacetophenone is typically produced through the reaction of bromine with acetophenone in the presence of a Lewis acid catalyst. This synthesis method yields a high purity product and allows for precise control over reaction conditions to optimize yield and purity.
2-Bromoacetophenone can be procured from specialty chemical suppliers or chemical manufacturers. It is typically shipped in sealed containers to prevent degradation and ensure product integrity during transport. Due to its potential reactivity and hazards, proper safety precautions must be taken during handling and transport to minimize the risk of accidents or contamination.
When procuring 2-Bromoacetophenone, it is essential to adhere to regulations and guidelines governing the handling and transportation of hazardous chemicals. Compliance with safety protocols and procedures is crucial to prevent accidents and ensure the safe and effective delivery of the compound. Additionally, it is advisable to work with reputable suppliers who adhere to strict quality control measures to guarantee the purity and integrity of the product.
⚠️ Safety Considerations
Safety Considerations for 2-Bromoacetophenone:
2-Bromoacetophenone, also known as α-bromoacetophenone, is a chemical compound commonly used in organic synthesis. It is important to handle this compound with caution due to its potential hazards. 2-Bromoacetophenone is classified as a hazardous substance and should be stored, handled, and disposed of according to strict safety guidelines. When working with 2-Bromoacetophenone, it is crucial to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat, to prevent skin contact, eye irritation, and inhalation of vapors. In addition, this compound should only be used in a well-ventilated area to minimize exposure to potentially harmful fumes. It is also essential to be aware of emergency procedures in case of accidental spills or exposure to 2-Bromoacetophenone.
Hazard Statements for 2-Bromoacetophenone:
Hazard statements for 2-Bromoacetophenone include “Causes skin irritation”, “Causes serious eye irritation”, “May cause respiratory irritation”, “Toxic if swallowed”, and “May cause genetic defects”. These statements indicate the potential dangers associated with exposure to 2-Bromoacetophenone, highlighting the importance of proper handling and safety precautions when working with this compound. It is crucial to minimize any possible contact with the skin, eyes, and respiratory system to prevent adverse effects.
Precautionary Statements for 2-Bromoacetophenone:
Precautionary statements for 2-Bromoacetophenone include “Wear protective gloves/protective clothing/eye protection/face protection”, “IF ON SKIN: Wash with plenty of soap and water”, “IF IN EYES: Rinse cautiously with water for several minutes”, “IF INHALED: Remove person to fresh air and keep comfortable for breathing”, and “IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell”. These statements emphasize the importance of taking necessary precautions to avoid exposure to 2-Bromoacetophenone and provide guidelines on how to respond in case of accidental contact or ingestion. It is imperative to follow these precautionary measures to ensure the safety of individuals handling this chemical compound.
🔬 Potential Research Directions
One potential research direction for 2-Bromoacetophenone lies in its use as an intermediate in the synthesis of various organic compounds. This compound can be further functionalized to yield molecules with diverse chemical properties, making it a versatile building block for drug discovery and material science research.
Additionally, studies focusing on the reactivity and selectivity of 2-Bromoacetophenone towards different nucleophiles could provide valuable insights into its synthetic potential. Exploring the mechanistic pathways of reactions involving this compound could lead to the development of more efficient and environmentally friendly synthetic methodologies.
Furthermore, investigations into the biological activity of 2-Bromoacetophenone and its derivatives could uncover new therapeutic applications. Understanding the interactions of this compound with biological targets may reveal potential drug candidates for the treatment of various diseases, offering new avenues for pharmaceutical research and development.
🧪 Related Compounds
One similar compound to 2-Bromoacetophenone based upon molecular structure is 4-Bromoacetophenone. This compound also contains a bromine atom attached to a phenyl ring, with the bromine atom located at the fourth carbon position from the carbonyl group. The presence of the bromine substituent imparts similar chemical reactivity and properties to 2-Bromoacetophenone.
Another related compound is 2-Chloroacetophenone, which shares a similar molecular structure with 2-Bromoacetophenone. In this compound, the bromine atom is replaced by a chlorine atom, resulting in similar reactivity and physical properties. The presence of the halogen substituent at the ortho position of the phenyl ring contributes to the compound’s chemical behavior and potential applications in various synthetic processes.
One more similar compound is 2-Iodoacetophenone, which features an iodine atom attached to the phenyl ring in a manner akin to 2-Bromoacetophenone. The iodine substituent imparts unique chemical properties and reactivity to this compound, allowing for diverse applications in organic synthesis. Like 2-Bromoacetophenone, 2-Iodoacetophenone can be used as a reagent in various chemical transformations due to its reactive nature.
