Tris(p-aminophenyl)methanol, a compound also known as TAPM, holds significant relevance in everyday life due to its versatility and wide range of applications. This molecule is commonly used in various industries such as pharmaceuticals, materials science, and chemical synthesis. In pharmaceuticals, TAPM can serve as a building block for drug development, contributing to the creation of new medicines. In materials science, it can be utilized for the synthesis of polymers and catalysts. Additionally, TAPM’s chemical properties make it valuable for academic research and development in the field of chemistry. Overall, the importance of Tris(p-aminophenyl)methanol lies in its role as a crucial component in various sectors that ultimately impact our daily lives.
Table of Contents:
Commercial Applications
Chemical & Physical Properties
Production & Procurement
Safety Considerations
Potential Research Directions
Related Compounds
Commercial Applications
Tris(p-aminophenyl)methanol, also known as TAPM, finds various commercial and industrial applications due to its inherent properties. It is commonly used as a ligand in the preparation of catalysts for olefin polymerization reactions. Additionally, TAPM is utilized in the production of specialty chemicals and as a reagent in organic synthesis.
In the field of drug and medication applications, Tris(p-aminophenyl)methanol has shown potential as a building block for the synthesis of biologically active compounds. Its versatile structure allows for modifications that can enhance drug efficacy and selectivity in pharmaceutical formulations. Furthermore, TAPM derivatives have been investigated for their antimicrobial and anticancer properties, making them promising candidates for future drug development.
Overall, Tris(p-aminophenyl)methanol’s significance extends beyond its commercial and industrial utility, making it a valuable compound in the realm of drug discovery and development. Its diverse applications highlight its potential in various industries, showcasing its importance in both chemical synthesis and pharmaceutical research.
Chemical & Physical Properties
Tris(p-aminophenyl)methanol appears as a white crystalline solid with no noticeable odor.
With a molar mass of 366.38 g/mol and a density of 1.45 g/cm3, Tris(p-aminophenyl)methanol is significantly heavier than common food items like sugar (molar mass of 342.3 g/mol, density of 1.59 g/cm3) and salt (molar mass of 58.44 g/mol, density of 2.16 g/cm3).
Tris(p-aminophenyl)methanol has a melting point of 273-275°C and a boiling point of 517-520°C, contrasting with common food items like butter (melting point of 32-35°C, boiling point above 100°C) and water (melting point of 0°C, boiling point of 100°C).
This compound is sparingly soluble in water and exhibits a low viscosity. This contrasts with common food items like sugar and salt, which are highly soluble in water and have a lower viscosity.
Production & Procurement
Tris(p-aminophenyl)methanol is typically produced through a multi-step synthesis process, starting with the reaction of p-nitrobenzaldehyde with hydroxylamine to form p-nitrobenzaldoxime. This compound is then reduced to p-aminophenylhydroxylamine using a reducing agent, followed by a condensation reaction with formaldehyde to yield Tris(p-aminophenyl)methanol.
Tris(p-aminophenyl)methanol can be procured from chemical suppliers who specialize in organic compounds. It is typically transported in tightly sealed containers to prevent contamination or degradation during transit. Due to its sensitive nature, it is important to handle and store Tris(p-aminophenyl)methanol according to recommended safety protocols to ensure its integrity upon arrival.
Safety Considerations
Safety considerations for Tris(p-aminophenyl)methanol are crucial due to its hazardous nature. It is important to handle this substance with caution to prevent any potential harm. Proper protective equipment such as gloves, goggles, and lab coats should be worn when working with Tris(p-aminophenyl)methanol to minimize exposure to the skin, eyes, and respiratory system.
Additionally, Tris(p-aminophenyl)methanol should be stored in a well-ventilated area away from heat sources and incompatible materials. It is essential to follow proper procedures for handling, storing, and disposing of this substance to ensure the safety of laboratory personnel and the surrounding environment. In case of accidental exposure or ingestion, immediate medical attention should be sought, and the relevant safety data sheet consulted for appropriate response measures.
Hazard statements for Tris(p-aminophenyl)methanol include “Causes skin irritation” and “May cause respiratory irritation.” These statements indicate potential risks associated with exposure to this compound. It is essential to take necessary precautions to avoid direct contact with the skin, eyes, or respiratory system when working with Tris(p-aminophenyl)methanol. Proper handling procedures and protective equipment should be used to minimize the risk of adverse health effects.
Precautionary statements for Tris(p-aminophenyl)methanol include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements outline specific actions to be taken to ensure safe handling of Tris(p-aminophenyl)methanol. It is important to follow these precautionary measures to reduce the risk of exposure and potential harm to individuals working with this compound. Proper safety protocols should be implemented to minimize the likelihood of accidents or injuries.
Potential Research Directions
One potential research direction for Tris(p-aminophenyl)methanol is the investigation of its application as a ligand in coordination chemistry. The complexation behavior of this compound with various metal ions could be studied to understand its potential as a catalyst or in molecular recognition processes.
Another avenue of research could involve exploring the potential medicinal properties of Tris(p-aminophenyl)methanol. Its structural features suggest possible interactions with biological macromolecules, making it a candidate for drug development or as a probe for studying biological systems.
Furthermore, research could focus on the synthesis and modification of Tris(p-aminophenyl)methanol derivatives to tailor their properties for specific applications. By fine-tuning its chemical structure, researchers could potentially enhance its solubility, stability, or reactivity, opening up new possibilities in diverse fields such as materials science and nanotechnology.
Related Compounds
One similar compound to Tris(p-aminophenyl)methanol based upon molecular structure is Tris(p-aminophenyl)phosphine. This compound contains three p-aminophenyl groups attached to a central phosphorus atom, similar to how Tris(p-aminophenyl)methanol has three p-aminophenyl groups attached to a central carbon atom. Tris(p-aminophenyl)phosphine is commonly used in organic chemistry as a ligand in transition metal complex catalysis.
Another similar compound to Tris(p-aminophenyl)methanol is Tris(p-aminophenyl)methane. This compound also contains three p-aminophenyl groups, but instead of being attached to a central carbon atom like in Tris(p-aminophenyl)methanol, they are attached to a central methane moiety. Tris(p-aminophenyl)methane has been studied for its potential applications in organic synthesis and materials science due to its unique structural properties.
A third compound with a similar molecular structure to Tris(p-aminophenyl)methanol is Tris(p-aminophenyl)amine. Like Tris(p-aminophenyl)methanol, this compound contains three p-aminophenyl groups. However, in Tris(p-aminophenyl)amine, these groups are attached to a central amine nitrogen atom instead of a central carbon atom. Tris(p-aminophenyl)amine is commonly used in organic synthesis and as a building block for the construction of complex molecules.
