Tributyltin hydride, a chemical compound commonly used in organic synthesis and industrial processes, may not directly impact individuals in their daily lives. However, its relevance lies in its potential to aid in the development of various products and technologies that ultimately contribute to advancements in pharmaceuticals, materials science, and other industries. Despite its limited direct impact on consumers, Tributyltin hydride plays a crucial role in driving innovation and progress in numerous sectors.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Tributyltin hydride, a chemical compound with the formula (C4H9)3SnH, has found several commercial and industrial applications. One primary use of tributyltin hydride is as a reducing agent in various chemical reactions, particularly in the synthesis of organic compounds. It is also used as a catalyst in the production of silicone polymers, providing improved efficiency in the manufacturing process.
In the realm of drug and medication applications, tributyltin hydride has shown potential as a reagent in the formation of carbon-carbon bonds. This property makes it useful in the development of pharmaceutical compounds and drug molecules. Additionally, tributyltin hydride has demonstrated antimicrobial activity, which is being explored for its potential application in antimicrobial drugs and treatments.
Overall, the commercial and industrial applications of tributyltin hydride extend to various sectors, from chemical production to pharmaceutical development. Its versatility as a reducing agent, catalyst, and antimicrobial agent highlights its importance in advancing scientific research and technological advancements in different fields.
⚗️ Chemical & Physical Properties
Tributyltin hydride is a colorless to light yellow liquid with a pungent odor. Its distinctive odor is due to the presence of tin in its chemical structure.
With a molar mass of 246.14 g/mol and a density of 1.250 g/cm3, tributyltin hydride is heavier than many common household items like water and ethanol. It is denser than both water (1 g/cm3) and ethanol (0.789 g/cm3).
Tributyltin hydride has a melting point of -97°C and a boiling point of 120-121°C. These values are higher than those of common household items such as water (melting point of 0°C, boiling point of 100°C) and ethanol (melting point of -114.1°C, boiling point of 78.37°C).
Tributyltin hydride is insoluble in water and has a low viscosity, making it difficult to dissolve and relatively less thick compared to substances commonly found in households like sugar or salt. Its low viscosity and insolubility in water make it unique in terms of solubility properties.
🏭 Production & Procurement
Tributyltin hydride, a colorless liquid chemical compound used in organic synthesis, is typically produced through the reaction of tributyltin chloride with lithium aluminum hydride. The resulting product is then distilled under reduced pressure to isolate the pure Tributyltin hydride.
Procuring Tributyltin hydride involves contacting chemical suppliers or manufacturers specializing in organotin compounds. Due to its sensitivity to air and moisture, the compound is usually transported in sealed containers under inert gas or vacuum conditions to avoid degradation.
Upon receipt, Tributyltin hydride should be stored in a cool, dry place away from sources of heat or flames. Proper labeling of containers and compliance with regulations regarding the handling of hazardous chemicals are essential when procuring and transporting this compound.
⚠️ Safety Considerations
Safety considerations for Tributyltin hydride include the fact that it is a highly flammable liquid and vapor, and can react violently with oxidizing agents. Care must be taken to avoid contact with skin and eyes, as it can cause severe irritation and burns. Proper ventilation is essential when handling Tributyltin hydride to prevent exposure to its harmful fumes.
In terms of pharmacology, Tributyltin hydride is a chemical compound that is primarily used as a reducing agent in organic synthesis. It is known for its ability to efficiently reduce various functional groups, such as ketones, aldehydes, and alkenes. Despite its usefulness in chemical reactions, Tributyltin hydride must be handled with caution due to its hazardous nature.
The hazard statements for Tributyltin hydride include “Fatal if swallowed,” “Causes skin and eye irritation,” and “May cause respiratory irritation.” It is classified as a Category 2 acute toxicity substance, meaning it can cause serious health effects if not handled properly. Individuals working with Tributyltin hydride should be aware of these hazards and take appropriate safety precautions to minimize risks.
Precautionary statements for Tributyltin hydride involve avoiding inhalation, skin contact, and ingestion. Protective measures such as wearing gloves, goggles, and a respiratory mask are recommended when working with this chemical. In case of exposure, immediate medical attention should be sought, and contaminated clothing should be removed promptly to prevent further contact with the skin. It is essential to store Tributyltin hydride in a cool, dry place away from sources of ignition and incompatible materials.
🔬 Potential Research Directions
One potential research direction for Tributyltin hydride involves exploring its use as a reducing agent in organic synthesis. This compound has shown promise in facilitating various chemical transformations, making it a subject of interest for chemists seeking novel ways to conduct reactions.
Another area of investigation could focus on the environmental impact of Tributyltin hydride. Given the toxicity and persistence of organotin compounds in the environment, understanding the behavior of this compound in natural systems is crucial for assessing its potential ecological risks.
Additionally, researchers may delve into the development of new synthetic methodologies utilizing Tributyltin hydride as a key reagent. By exploring its reactivity and selectivity in different types of reactions, scientists can uncover innovative strategies for achieving complex chemical transformations efficiently and selectively.
🧪 Related Compounds
One similar compound to Tributyltin hydride based upon molecular structure is Triethyltin hydride (Et3SnH). This compound also belongs to the organotin hydride family and shares structural similarities with Tributyltin hydride. Triethyltin hydride contains three ethyl groups and one hydrogen atom bonded to a tin atom, similar to how Tributyltin hydride contains three butyl groups and one hydrogen atom bonded to a tin atom.
Another compound with a comparable molecular structure to Tributyltin hydride is Trimethyltin hydride (Me3SnH). In this compound, three methyl groups and one hydrogen atom are attached to a tin atom, resembling the structure of Tributyltin hydride. Despite the different alkyl groups present in Trimethyltin hydride compared to Tributyltin hydride, the basic molecular arrangement remains similar with the tin atom at the center.
Diphenyltin hydride (Ph2SnH) is yet another compound that bears resemblance to Tributyltin hydride in terms of molecular structure. Instead of alkyl groups, Diphenyltin hydride contains two phenyl groups and one hydrogen atom bonded to a tin atom. This compound exhibits similar structural characteristics to Tributyltin hydride, with the central tin atom coordinating with two aryl groups and one hydrogen atom.
