Trans-4-Hydroxycyclohexanecarboxylic acid, although a complex chemical compound, holds notable importance in everyday life due to its role in the pharmaceutical industry. This compound serves as a key building block in the synthesis of various drugs, particularly those targeting neurological disorders and inflammation. Its versatile nature and significance in drug development make trans-4-Hydroxycyclohexanecarboxylic acid a crucial component in the advancement of medical treatments that impact individuals globally.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Trans-4-Hydroxycyclohexanecarboxylic acid is commonly used in the commercial and industrial sector as a key ingredient in the production of certain polymers and resins. Its chemical properties allow for the creation of materials with specific characteristics such as high heat resistance and durability, making it valuable in the manufacturing of various industrial products.
In the pharmaceutical industry, trans-4-Hydroxycyclohexanecarboxylic acid has shown potential as a precursor in the synthesis of certain drug compounds. Its unique structure and reactivity make it a valuable building block in the development of medications aimed at treating a range of health conditions. Researchers continue to explore its pharmaceutical applications for potential therapeutic benefits.
⚗️ Chemical & Physical Properties
Trans-4-Hydroxycyclohexanecarboxylic acid appears as a white crystalline solid with no distinct odor.
It has a molar mass of approximately 182.20 g/mol and a density of about 1.28 g/cm3. Compared to common food items such as sugar (180.16 g/mol) and salt (58.44 g/mol), trans-4-Hydroxycyclohexanecarboxylic acid has a higher molar mass. In terms of density, it is higher than sugar (1.59 g/cm3) but lower than salt (2.16 g/cm3).
The melting point of trans-4-Hydroxycyclohexanecarboxylic acid is around 197-201 °C, while the boiling point is approximately 435 °C. These values are higher compared to common food items like sugar (melting point 186 °C, boiling point 368 °C) and salt (melting point 801 °C, boiling point 1465 °C).
Trans-4-Hydroxycyclohexanecarboxylic acid is sparingly soluble in water and exhibits low viscosity. Compared to common food items like sugar and salt, which are highly soluble in water and have low viscosity, trans-4-Hydroxycyclohexanecarboxylic acid has lesser solubility and higher viscosity.
🏭 Production & Procurement
trans-4-Hydroxycyclohexanecarboxylic acid is typically produced through a multistep synthesis process starting with cyclohexanone. The reaction involves the conversion of cyclohexanone to its corresponding oxime, followed by reduction to form the desired trans-4-Hydroxycyclohexanecarboxylic acid. This process requires careful control of reaction conditions and purification steps to obtain the final product in high yield and purity.
The procurement of trans-4-Hydroxycyclohexanecarboxylic acid involves sourcing the necessary starting materials and reagents, as well as securing the equipment and facilities for the synthesis process. Once the compound is produced, it can be isolated through various purification techniques such as recrystallization or column chromatography. Once purified, trans-4-Hydroxycyclohexanecarboxylic acid can be stored in airtight containers and transported under controlled conditions to prevent degradation or contamination.
Transportation of trans-4-Hydroxycyclohexanecarboxylic acid may involve shipping the compound in sealed containers or vials to prevent exposure to moisture, air, or light. It is crucial to follow proper handling and storage procedures to ensure the stability and integrity of the compound during transportation. Depending on the quantity and destination, shipping methods may vary, with consideration given to temperature control and regulatory requirements for hazardous materials.
⚠️ Safety Considerations
Safety considerations for trans-4-Hydroxycyclohexanecarboxylic acid should be taken seriously due to its potential hazards. This compound may cause skin irritation and could be harmful if swallowed. It is important to handle this substance with care and to wear appropriate protective equipment when working with it.
When handling trans-4-Hydroxycyclohexanecarboxylic acid, it is important to be aware of the hazard statements associated with this compound. Some of the key hazard statements include “Causes skin irritation” and “Harmful if swallowed.” These statements highlight the potential dangers of exposure to this substance and emphasize the importance of following proper safety protocols when working with it.
Precautionary statements for trans-4-Hydroxycyclohexanecarboxylic acid provide guidance on how to safely handle and store this compound. It is advised to wear protective gloves and eye protection when working with this substance to avoid skin and eye irritation. Additionally, it is recommended to store trans-4-Hydroxycyclohexanecarboxylic acid in a cool, dry place away from incompatible materials to prevent any accidents or incidents. Following these precautions will help ensure the safe handling of this compound and minimize the risk of exposure.
🔬 Potential Research Directions
Potential research directions for trans-4-Hydroxycyclohexanecarboxylic acid could involve exploring its pharmacological properties and potential applications in drug development. Studies could focus on investigating its interaction with biological targets and elucidating its mechanism of action.
Furthermore, research efforts could be directed towards understanding the synthesis and metabolism of trans-4-Hydroxycyclohexanecarboxylic acid in living organisms. This would contribute to our knowledge of its bioavailability, distribution, and excretion, which are important factors in determining its pharmacokinetic profile.
Additionally, investigations into the structure-activity relationship of trans-4-Hydroxycyclohexanecarboxylic acid derivatives could provide valuable insights into optimizing its pharmacological properties. This could lead to the development of novel analogs with improved efficacy and reduced side effects, paving the way for the discovery of new drug candidates.
🧪 Related Compounds
One similar compound to trans-4-Hydroxycyclohexanecarboxylic acid is cis-4-Hydroxycyclohexanecarboxylic acid. In this compound, the hydroxyl (-OH) group and carboxylic acid group are in a cis configuration, meaning they are on the same side of the cyclohexane ring. This structural arrangement may result in different physical and chemical properties compared to trans-4-Hydroxycyclohexanecarboxylic acid.
Another similar compound is 4-Hydroxycyclohexanecarboxylic acid. This compound lacks the trans or cis designation, indicating that the position of the hydroxyl and carboxylic acid groups on the cyclohexane ring is unspecified. The lack of stereochemistry in this compound may impact its reactivity and biological activity compared to trans-4-Hydroxycyclohexanecarboxylic acid.
Additionally, trans-4-Methylcyclohexanecarboxylic acid is structurally similar to trans-4-Hydroxycyclohexanecarboxylic acid. In this compound, a methyl (-CH3) group is present in place of the hydroxyl group. The presence of the methyl group may alter the compound’s physical properties and interactions with other molecules. Comparing these similar compounds can provide insight into the effects of structural modifications on compound behavior.
