Tetrahydropyran-2-methanol 

Tetrahydropyran-2-methanol is a chemical compound that holds importance in everyday life, specifically in the pharmaceutical and food industries. It serves as a versatile building block for the synthesis of various drugs, flavors, and fragrances. Additionally, it can be found in consumer products such as cosmetics and household cleaners. The compound’s unique structure and properties make it a valuable ingredient in a wide range of products that impact the daily lives of individuals worldwide.

Table of Contents:

💡  Commercial Applications

Tetrahydropyran-2-methanol, also known as THPM, is a versatile compound with various commercial and industrial applications.

In the commercial sector, THPM is commonly used as a starting material in the synthesis of fragrances and flavors due to its pleasant aroma profile. Additionally, it is utilized in the production of surfactants and lubricants for various industrial purposes.

In the pharmaceutical industry, THPM has shown potential applications in drug and medication development. It has been studied for its antiviral and antibacterial properties, making it a promising candidate for the formulation of new therapeutic agents. Further research is ongoing to explore its potential in combating infectious diseases and other health conditions.

⚗️  Chemical & Physical Properties

Tetrahydropyran-2-methanol appears as a colorless liquid with a faint, sweet odor. Its chemical structure consists of a six-membered ring containing an oxygen atom, giving it a unique and distinct composition.

The molar mass of Tetrahydropyran-2-methanol is approximately 104.15 g/mol, and its density is around 1.05 g/cm3. Compared to common food items, Tetrahydropyran-2-methanol has a lower molar mass but a similar density to water.

The melting point of Tetrahydropyran-2-methanol is around -40 degrees Celsius, and its boiling point is approximately 165 degrees Celsius. These values are lower than those of many common food items, such as sugar and salt, which have higher melting and boiling points.

Tetrahydropyran-2-methanol is soluble in water and has a relatively low viscosity. In comparison to common food items, it has similar solubility to sugar and salt but lower viscosity compared to honey or syrup.

🏭  Production & Procurement

Tetrahydropyran-2-methanol, commonly known as THP-2-ol, is produced through a multistep synthesis process. The starting material for the synthesis is typically readily available and inexpensive, making the production cost-effective. The synthesis involves various chemical reactions that convert the starting material into the desired Tetrahydropyran-2-methanol product.

Once produced, Tetrahydropyran-2-methanol can be procured from chemical suppliers or laboratories specializing in organic synthesis. It is typically available in varying quantities, ranging from small-scale research supplies to bulk quantities for industrial use. The compound can be transported in sealed containers to prevent contamination and degradation during transit.

The procurement and transportation of Tetrahydropyran-2-methanol must adhere to strict safety guidelines and regulations to ensure the integrity of the compound. Proper labeling and documentation are essential for tracking and monitoring the compound during procurement and transportation. Additionally, the storage conditions must be carefully controlled to prevent any degradation or contamination of Tetrahydropyran-2-methanol.

⚠️  Safety Considerations

Safety considerations for Tetrahydropyran-2-methanol include its flammability and potential for skin and eye irritation. This compound should be handled with care in a well-ventilated area, and appropriate personal protective equipment should be worn when working with it. Additionally, Tetrahydropyran-2-methanol should be stored in a cool, dry place away from sources of ignition.

Hazard statements for Tetrahydropyran-2-methanol include “Causes skin irritation” and “Causes serious eye irritation.” This compound may also be harmful if swallowed or inhaled, and prolonged or repeated exposure may lead to dermatitis. It is important to follow proper safety protocols when working with Tetrahydropyran-2-methanol to minimize the risk of these hazards.

Precautionary statements for Tetrahydropyran-2-methanol include “Avoid breathing vapors, mist, or spray” and “Wear protective gloves/eye protection/face protection.” In case of skin contact, wash with plenty of soap and water, and in case of eye contact, rinse cautiously with water for several minutes. It is recommended to seek medical attention if irritation persists. Additionally, Tetrahydropyran-2-methanol should be kept out of reach of children and stored in a secure location.

🔬  Potential Research Directions

Potential research directions for Tetrahydropyran-2-methanol include exploring its further synthetic applications in the organic chemistry field. Due to its unique structure and versatile reactivity, Tetrahydropyran-2-methanol may be investigated for its potential use in the development of new pharmaceuticals or agrochemicals.

Additionally, studies may focus on understanding the mechanisms of reactions involving Tetrahydropyran-2-methanol in order to optimize its use as a reagent in various chemical transformations. This could lead to the discovery of novel synthetic methodologies or the improvement of existing protocols, ultimately contributing to the advancement of organic synthesis.

Furthermore, research efforts may be directed towards investigating the biological activities of Tetrahydropyran-2-methanol and its derivatives. By studying the interactions of this compound with biological systems, researchers may uncover potential therapeutic properties or other applications in the fields of medicine or biotechnology.

One similar compound to Tetrahydropyran-2-methanol is Tetrahydropyran-4-methanol. This compound has a similar molecular structure, with a four-membered ring containing an oxygen atom and a hydroxyl group attached to the second carbon atom. Tetrahydropyran-4-methanol may exhibit similar chemical properties and reactivity to Tetrahydropyran-2-methanol due to their structural similarities.

Another related compound is 2-Methyltetrahydropyran-2-methanol. In this compound, a methyl group is attached to the second carbon atom of the tetrahydropyran ring. This substitution can lead to changes in the physical and chemical properties of the compound compared to Tetrahydropyran-2-methanol. The presence of the methyl group may affect the compound’s solubility, reactivity, or biological activity.

A third compound with a similar structure is Tetrahydropyran-3-methanol. This compound contains a hydroxyl group attached to the third carbon atom of the tetrahydropyran ring, similar to Tetrahydropyran-2-methanol. The position of the hydroxyl group in the ring can influence the compound’s stereochemistry and reactivity, leading to potential differences in its properties compared to Tetrahydropyran-2-methanol.

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