Phenyl aminosalicylate, also known as PAS, is a medication that is primarily used in the treatment of tuberculosis. This antibiotic plays a crucial role in combating the spread of this infectious disease by effectively killing the bacteria responsible for its development. The relevance of PAS to everyday life lies in its ability to aid in the recovery and well-being of individuals affected by tuberculosis, ultimately reducing the overall impact of the disease on public health. Its importance cannot be understated when considering the global efforts to control and eradicate tuberculosis, making it a significant component of modern healthcare practices.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Phenyl Aminosalicylate, commonly known as PAS, has commercial and industrial applications as a chemical intermediate in the production of various products, such as dyes, pigments, and pharmaceuticals. Its ability to undergo various chemical reactions makes it a versatile compound for use in the manufacturing industry.
In the field of drug and medication applications, PAS is used primarily as an antibiotic for the treatment of tuberculosis. Its bacteriostatic properties inhibit the growth of the tuberculosis-causing bacteria, making it a vital component in the treatment regimen for this infectious disease. Additionally, PAS has been explored for its potential anti-inflammatory and immunomodulatory properties in the treatment of certain autoimmune diseases.
In pharmaceutical applications, PAS is commonly formulated into oral tablets or capsules for easy administration to patients. The dosage and frequency of PAS administration are carefully controlled to ensure maximum efficacy in treating tuberculosis and minimizing the risk of adverse effects. Its long history of use in the medical field has solidified its role as a cornerstone treatment for tuberculosis, particularly in cases of drug-resistant strains.
⚗️ Chemical & Physical Properties
Phenyl Aminosalicylate appears as a white crystalline solid with a faint odor. It is a chemical compound that is commonly used in pharmaceuticals.
The molar mass of Phenyl Aminosalicylate is approximately 289.30 g/mol, and it has a density of 1.44 g/cm3. When compared to common food items such as sugar (molar mass of 342.30 g/mol, density of 1.59 g/cm3) and salt (molar mass of 58.44 g/mol, density of 2.16 g/cm3), Phenyl Aminosalicylate has a lower molar mass and density.
The melting point of Phenyl Aminosalicylate ranges from 185-190°C, and the boiling point is approximately 345°C. In comparison to common food items such as butter (melting point of 32-35°C, boiling point of 150-200°C) and chocolate (melting point of 34-38°C, boiling point of 120°C), Phenyl Aminosalicylate has significantly higher melting and boiling points.
Phenyl Aminosalicylate is sparingly soluble in water and has a low viscosity. Compared to common food items like sugar (high solubility in water, low viscosity) and olive oil (insoluble in water, low viscosity), Phenyl Aminosalicylate exhibits lower solubility and viscosity in water.
🏭 Production & Procurement
Phenyl Aminosalicylate, also known as PAS, is typically produced through a multi-step chemical synthesis process in a laboratory setting. This process involves the combination of various chemicals and reactive compounds to form the final product. The synthesis of Phenyl Aminosalicylate requires precise control of temperature, pressure, and reaction times to ensure a high-quality product.
Phenyl Aminosalicylate can be procured from pharmaceutical companies or chemical suppliers that specialize in the production of pharmaceutical intermediates. The compound is often available in both bulk powder form and pre-made tablets or capsules for easy administration. Transportation of Phenyl Aminosalicylate typically occurs in sealed containers or packaging to prevent contamination or degradation during transit.
When procuring Phenyl Aminosalicylate, it is important to ensure that the supplier complies with all necessary quality control standards and regulations to guarantee the purity and safety of the product. This may involve obtaining certificates of analysis, batch records, and manufacturing documentation to verify the authenticity of the compound. Proper storage and handling of Phenyl Aminosalicylate are essential to maintain its stability and efficacy until it reaches its final destination for use in medical treatment or research.
⚠️ Safety Considerations
Safety considerations for Phenyl Aminosalicylate, also known as PAS, include the potential for skin and eye irritation upon contact. It is important to wear appropriate protective equipment, such as gloves and goggles, when handling this compound. Additionally, proper ventilation should be maintained to prevent inhalation of vapors.
When working with Phenyl Aminosalicylate, it is crucial to store it in a secure and well-ventilated area, away from sources of heat or flames. This compound should be kept in a tightly sealed container to prevent spills or inadvertent exposure. In case of accidental ingestion, contact a medical professional immediately and provide information on the product for proper treatment.
Hazard statements for Phenyl Aminosalicylate include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential risks associated with exposure to this compound. It is important to take necessary precautions to minimize the chances of skin or eye contact when working with Phenyl Aminosalicylate to avoid harm.
Precautionary statements for Phenyl Aminosalicylate include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.” These statements emphasize the importance of using appropriate protective gear and taking immediate action in case of eye contact. Following these precautions can help minimize the potential risks associated with handling Phenyl Aminosalicylate.
🔬 Potential Research Directions
Research on Phenyl Aminosalicylate has the potential to explore its efficacy in treating various gastrointestinal disorders, such as inflammatory bowel disease and Crohn’s disease. Studies could investigate its mechanism of action at the molecular level, shedding light on how it interacts with intestinal cells and inflammatory pathways.
Another promising research direction for Phenyl Aminosalicylate is its potential use in combination therapy with other drugs to enhance therapeutic effects and reduce side effects. Researchers could explore synergistic effects with antibiotics or immunosuppressive agents to optimize treatment outcomes in patients with refractory gastrointestinal conditions.
Furthermore, investigations into the pharmacokinetics and pharmacodynamics of Phenyl Aminosalicylate could provide valuable insights into dosing regimens, patient-specific factors affecting drug response, and potential drug interactions. Understanding these aspects could improve treatment strategies and personalized medicine approaches for individuals with gastrointestinal disorders.
🧪 Related Compounds
One similar compound to Phenyl Aminosalicylate based upon molecular structure is Ethylenediaminetetraacetic Acid (EDTA). EDTA is a chelating agent that contains four carboxylic acid groups, allowing it to bind to metal ions. The molecular structure of EDTA contains multiple amine and carboxylic acid functional groups, similar to the structure of Phenyl Aminosalicylate.
Another compound with a similar molecular structure to Phenyl Aminosalicylate is 4-Aminobenzoic Acid (PABA). PABA is a precursor to folic acid and is commonly used in sunscreen formulations. The presence of an amino group and a carboxylic acid group in the molecular structure of PABA makes it comparable to Phenyl Aminosalicylate.
A third compound that shares a resemblance in molecular structure to Phenyl Aminosalicylate is Sulfanilamide. Sulfanilamide is an antibacterial agent that contains an amine group and a sulfonamide group in its structure. This similarity in functional groups to Phenyl Aminosalicylate allows for comparisons in terms of chemical reactivity and biological activity.
