Oxyphenbutazone is a nonsteroidal anti-inflammatory drug that was once used to treat various inflammatory conditions. It has since been withdrawn from the market due to its potentially severe side effects, such as causing liver damage and aplastic anemia. While it may not have direct relevance to everyday life currently, the drug serves as a cautionary tale about the importance of drug safety regulations and the potential risks associated with certain medications.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Oxyphenbutazone, a nonsteroidal anti-inflammatory drug (NSAID), has limited commercial and industrial applications due to its primary use as a medication for pain relief and inflammation reduction in humans.
In the realm of drug and medication applications, Oxyphenbutazone is known for its potent analgesic and anti-inflammatory properties, making it a valuable treatment option for conditions such as arthritis, gout, and other inflammatory disorders.
Although Oxyphenbutazone was once widely used in the treatment of certain medical conditions, its commercial and industrial applications have diminished over time with the introduction of newer, safer NSAIDs with fewer side effects and risks.
While Oxyphenbutazone may still be utilized in some countries for specific medical purposes, its commercial and industrial relevance has waned as newer medications have emerged to provide more effective and safer alternatives for pain management and inflammation control.
⚗️ Chemical & Physical Properties
Oxyphenbutazone appears as a white crystalline powder with no distinct odor, making it relatively odorless compared to other chemical compounds.
With a molar mass of 308.35 g/mol and a density of 1.38 g/cm³, Oxyphenbutazone is heavier and denser than common food items like sugar or salt.
Oxyphenbutazone has a melting point of 105-107°C and a boiling point of 360°C, which is significantly higher than the melting and boiling points of most common food items.
Oxyphenbutazone is sparingly soluble in water and has a relatively low viscosity. This contrasts with common food items which are typically more soluble in water and have lower viscosity.
🏭 Production & Procurement
Oxyphenbutazone, also known as Tandearil, is a nonsteroidal anti-inflammatory drug (NSAID) that has been synthesized for its analgesic and anti-inflammatory properties. The production of Oxyphenbutazone involves combining the chemical compound phenylbutazone with oxygen to form the final product. This chemical synthesis process typically occurs in a laboratory setting under controlled conditions to ensure the purity and efficacy of the drug.
Once Oxyphenbutazone has been produced, it can be procured through pharmaceutical companies or wholesalers who distribute the drug to healthcare providers and pharmacies. The procurement of Oxyphenbutazone may involve obtaining the drug through a prescription from a licensed healthcare provider or purchasing it from a licensed pharmacy. The transportation of Oxyphenbutazone is typically carried out using standard shipping methods, such as air freight or ground transportation, to ensure the timely delivery of the drug to its intended destination.
In some cases, Oxyphenbutazone may be procured through international suppliers who manufacture and distribute the drug to countries around the world. The procurement and transportation of Oxyphenbutazone from international suppliers may involve additional regulatory steps, such as customs clearance and import restrictions, to ensure compliance with local laws and regulations. Overall, the production and procurement of Oxyphenbutazone require careful attention to detail and adherence to stringent quality control standards to ensure the safe and effective use of the drug.
⚠️ Safety Considerations
Safety considerations for Oxyphenbutazone include the potential for liver toxicity, gastrointestinal bleeding, and kidney damage. Due to these risks, it is important to use this medication with caution and under the supervision of a healthcare professional. Additionally, Oxyphenbutazone should not be used in patients with a history of allergic reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) or in those with a history of stomach ulcers.
The hazard statements for Oxyphenbutazone include the potential for serious health effects if not used properly. This medication has the potential to cause harm to the liver, kidneys, and gastrointestinal system. It is important to follow dosage instructions carefully and to report any adverse reactions to a healthcare provider promptly.
Precautionary statements for Oxyphenbutazone include the need to avoid alcohol consumption while taking this medication. Alcohol can increase the risk of liver damage when combined with Oxyphenbutazone. Patients should also be cautious about using other medications that may interact with Oxyphenbutazone and should consult with a healthcare provider before starting any new medications while taking Oxyphenbutazone.
🔬 Potential Research Directions
Potential research directions for Oxyphenbutazone may include further investigation into its pharmacokinetics and metabolism in humans, particularly in different patient populations such as the elderly or those with renal impairment. Studies could also explore the drug’s efficacy and safety profile compared to other nonsteroidal anti-inflammatory drugs, as well as its potential for combination therapy with other medications.
Researchers may also focus on the long-term effects of Oxyphenbutazone on organ systems such as the liver, kidney, and cardiovascular system. This could involve conducting clinical trials to assess the drug’s impact on these organs over an extended period of time. Additionally, studies could investigate the drug’s potential use in treating specific conditions such as chronic pain, inflammation, or certain types of arthritis.
Future research on Oxyphenbutazone could involve exploring its mechanism of action at the molecular level and identifying specific molecular targets that may be responsible for its therapeutic effects. This could lead to the development of more targeted drug therapies that offer improved efficacy and reduced side effects. Additionally, studies could investigate potential drug interactions with Oxyphenbutazone and how these interactions may impact its pharmacological profile and safety.
🧪 Related Compounds
One similar compound to Oxyphenbutazone based on its molecular structure is Phenylbutazone. This compound also belongs to the class of nonsteroidal anti-inflammatory drugs and is commonly used to treat pain and inflammation associated with conditions such as arthritis. Like Oxyphenbutazone, Phenylbutazone has a phenyl ring and a butyl chain in its molecular structure, which contribute to its analgesic and anti-inflammatory properties.
Another compound structurally similar to Oxyphenbutazone is Mofebutazone. Also known as Methylbutazone, this drug is another nonsteroidal anti-inflammatory drug with a similar pharmacological profile to Oxyphenbutazone. Mofebutazone contains a methyl group instead of an ethyl group like Oxyphenbutazone, but both compounds share a similar backbone structure that contributes to their anti-inflammatory effects.
Additionally, another similar compound to Oxyphenbutazone is Clofezone. This drug is also a nonsteroidal anti-inflammatory agent with a similar chemical structure to Oxyphenbutazone. Clofezone contains a chlorine atom in its molecular structure, which differentiates it from Oxyphenbutazone; however, both compounds share similar functional groups that contribute to their anti-inflammatory activity.
