Orotidylic acid, also known as uridine monophosphate, plays a crucial role in the synthesis of RNA and a precursor to deoxyribonucleic acid (DNA) production. This molecule is essential for the proper functioning of cells and is involved in numerous biochemical processes, such as energy metabolism and cell signaling. In everyday life, orotidylic acid is significant as it contributes to the maintenance of overall cellular health and function. Its importance lies in its impact on various biological functions, making it a fundamental component in sustaining life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Orotidylic acid, also known as OMP or 5′-Orotidylic acid, has various commercial and industrial applications. One of the main uses of orotidylic acid is as a precursor in the biosynthesis of pyrimidine nucleotides, which are essential for nucleic acid production. It is also utilized in the production of certain pharmaceuticals and biofuels due to its role in nucleotide biosynthesis.
In the pharmaceutical industry, orotidylic acid plays a crucial role in the development of drugs and medications. It is a key intermediate in the synthesis of some antiviral and anticancer agents. Orotidylic acid is also used in the creation of drugs that target cellular processes involving nucleotide metabolism, making it a valuable compound in the pharmaceutical field.
Orotidylic acid’s importance in drug development extends to its role in the treatment of various medical conditions. It is used in medications that target viral infections, such as hepatitis B and HIV. Additionally, orotidylic acid is involved in the synthesis of drugs that combat certain types of cancers by disrupting nucleotide synthesis in cancer cells. Its versatility and significance in drug applications make orotidylic acid a valuable compound in the medical field.
⚗️ Chemical & Physical Properties
Orotidylic acid, also known as OMP, is a colorless crystalline solid with no distinct odor. It is commonly found in organisms as an intermediate in the biosynthesis of pyrimidine nucleotides.
The molar mass of orotidylic acid is approximately 354.2 g/mol, with a density of about 1.60 g/cm³. This places it in the same range as common food items such as sucrose (342.3 g/mol, 1.587 g/cm³) and table salt (58.44 g/mol, 2.165 g/cm³).
Orotidylic acid has a melting point of around 157-158°C and a boiling point of approximately 525°C. These values are significantly higher than those of common food items like butter (melting point: 32-35°C) and water (boiling point: 100°C).
Orotidylic acid is highly soluble in water, forming a clear and colorless solution. It also exhibits low viscosity, similar to that of common food items such as vinegar and honey.
🏭 Production & Procurement
Orotidylic acid, also known as 5′-OMP, is a nucleotide that serves as an important intermediate in the biosynthesis of pyrimidine nucleotides. It is produced in cells through a series of enzymatic reactions involving orotic acid and phosphoribosyl pyrophosphate.
Orotidylic acid can be procured through chemical synthesis in a laboratory setting. This involves the combination of orotic acid with ribose-5-phosphate in the presence of enzymes or chemical catalysts to form the desired nucleotide. Once produced, Orotidylic acid can be transported in its active form or as a stable derivative for further research or commercial applications.
In order to ensure the stability and integrity of Orotidylic acid during transportation, specialized storage conditions may be necessary. It is recommended to store Orotidylic acid at temperatures below freezing in a tightly sealed container to prevent degradation. Proper labeling and documentation of its properties are also essential for tracking and traceability purposes.
⚠️ Safety Considerations
Safety considerations for Orotidylic acid, also known as uridine monophosphate, must be taken into account due to its potential hazards. This compound should be handled with care and stored in a cool, dry place. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with Orotidylic acid to prevent skin contact or inhalation of its dust or vapors.
Hazard statements for Orotidylic acid include its potential to cause skin irritation, eye irritation, and respiratory irritation. It may also be harmful if swallowed or if it comes into contact with the skin. Furthermore, Orotidylic acid may cause damage to organs through prolonged or repeated exposure. It is essential to handle this compound with caution and follow proper safety procedures to minimize the risk of harm.
Precautionary statements for Orotidylic acid emphasize the need for proper storage and handling to prevent accidents or exposure. Avoid inhaling dust, vapors, or mist, and ensure adequate ventilation in the working area. In case of skin contact, immediately wash with plenty of soap and water. If Orotidylic acid is swallowed or if symptoms of exposure occur, seek medical advice and provide the product label or safety data sheet to healthcare professionals for proper treatment guidance. It is crucial to follow all safety recommendations to prevent any potential risks associated with Orotidylic acid.
🔬 Potential Research Directions
One potential research direction for orotidylic acid involves investigating its role in nucleotide biosynthesis pathways. Understanding the enzymatic reactions and regulatory mechanisms that control the production of orotidylic acid may lead to insights into genetic disorders and cancers linked to nucleotide synthesis.
Additionally, further studies could explore the potential therapeutic applications of orotidylic acid in treating diseases associated with nucleotide metabolism perturbations. Examining the effects of modulating orotidylic acid levels on cellular proliferation and differentiation could provide valuable information for drug development and precision medicine strategies.
Furthermore, research efforts may focus on elucidating the molecular interactions of orotidylic acid with other cellular components. Studying the binding partners and signaling pathways involved in orotidylic acid function could offer new perspectives on its physiological roles and potential targets for pharmacological intervention.
🧪 Related Compounds
One similar compound to Orotidylic acid is Uridylic acid (UMP), which also has a ribose sugar attached to the phosphate group. Like Orotidylic acid, Uridylic acid is involved in nucleotide biosynthesis and is a precursor to RNA synthesis in cells. The main difference between the two compounds is that Uridylic acid contains uracil as the nitrogenous base instead of orotic acid.
Another similar compound to Orotidylic acid is Cytidylic acid (CMP), which also contains a ribose sugar attached to the phosphate group. Cytidylic acid is a precursor to the synthesis of DNA and RNA, similar to Orotidylic acid. The key distinction between the two compounds is that Cytidylic acid has cytosine as the nitrogenous base, while Orotidylic acid contains orotic acid as the base.
A third similar compound to Orotidylic acid is Adenylic acid (AMP), which also has a ribose sugar attached to the phosphate group. Adenylic acid serves as a precursor to the synthesis of DNA, RNA, and ATP in cells, similar to Orotidylic acid’s role in nucleotide biosynthesis. The primary difference between the two compounds is that Adenylic acid contains adenine as the nitrogenous base, while Orotidylic acid contains orotic acid.
