N,N-Dimethylaniline N-oxide is a chemical compound that is primarily utilized as a reagent in various organic synthesis reactions. Despite its limited direct impact on daily life, this compound plays a crucial role in the development of pharmaceuticals, agrochemicals, and other advanced materials. Its ability to facilitate complex chemical transformations is essential in the production of many essential products, contributing to the advancement of science and technology in multiple industries.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N,N-Dimethylaniline N-oxide is commonly used in commercial and industrial applications as a stabilizer in rubber compounds, antioxidants in lubricants, and a catalyst in polymerization reactions. Its ability to enhance the thermal stability and oxidation resistance of materials makes it a valuable additive in various industrial processes. Additionally, it is utilized as a reagent in organic synthesis and as a corrosion inhibitor in metalworking fluids.
In the realm of drug and medication applications, N,N-Dimethylaniline N-oxide has been studied for its potential pharmacological properties. Some research suggests that it may have anti-inflammatory and antioxidant effects, making it a candidate for the development of drugs targeting oxidative stress-related disorders. However, further research is needed to fully understand its therapeutic potential and ensure its safety for human consumption.
⚗️ Chemical & Physical Properties
N,N-Dimethylaniline N-oxide is a white crystalline solid with a slight amine-like odor. This compound is typically found in a powder form, and is sparingly soluble in water.
The molar mass of N,N-Dimethylaniline N-oxide is approximately 141.21 g/mol, with a density of about 1.09 g/cm3. Compared to common household items, this compound has a higher molar mass than water (18.02 g/mol) and a similar density to water (1 g/cm3).
The melting point of N,N-Dimethylaniline N-oxide is around 69-72°C, while the boiling point is approximately 276-280°C. In comparison to common household items, this compound has a higher melting and boiling point than water (0°C and 100°C, respectively).
N,N-Dimethylaniline N-oxide is slightly soluble in water, but more soluble in organic solvents. Its viscosity is relatively low compared to other organic compounds. In contrast, common household items such as salt and sugar have higher solubility in water, and honey has a higher viscosity than N,N-Dimethylaniline N-oxide.
🏭 Production & Procurement
N,N-Dimethylaniline N-oxide, also known as N,N-DMAO, is commonly produced through the oxidation of N,N-Dimethylaniline with a suitable oxidant like hydrogen peroxide or peracetic acid. This process typically occurs in a controlled environment at moderate temperatures to ensure the efficiency of the reaction.
Once produced, N,N-Dimethylaniline N-oxide is typically procured from chemical suppliers or manufacturers who specialize in the production of organic compounds. It is often transported in sealed containers to prevent any potential degradation or contamination during transit. Proper labeling and handling instructions are provided to ensure the safe transportation of this compound.
In some cases, N,N-Dimethylaniline N-oxide may also be synthesized on-site in research laboratories or chemical facilities for specific applications. Careful consideration must be given to the handling and storage of this compound, as it can be potentially hazardous if not managed properly. Proper safety precautions and protocols should be followed to minimize any risks associated with handling N,N-Dimethylaniline N-oxide.
⚠️ Safety Considerations
Safety considerations for N,N-Dimethylaniline N-oxide include proper storage and handling to prevent exposure to the substance. It is essential to use appropriate personal protective equipment such as gloves, goggles, and lab coat when working with this compound. Additionally, it is crucial to follow proper disposal procedures to mitigate environmental hazards.
The pharmacology of N,N-Dimethylaniline N-oxide involves its role as an intermediate in the production of various chemicals and pharmaceuticals. This compound is used in the synthesis of dyes, polymers, and corrosion inhibitors. It is also utilized as a catalyst in certain chemical reactions due to its unique chemical properties.
Hazard statements for N,N-Dimethylaniline N-oxide include its classification as harmful if swallowed, in contact with skin, or if inhaled. This compound may cause irritation to the skin, eyes, and respiratory system. Prolonged or repeated exposure to N,N-Dimethylaniline N-oxide could lead to serious health effects, and it is important to avoid direct contact with the substance.
Precautionary statements for N,N-Dimethylaniline N-oxide involve wearing appropriate personal protective equipment, including gloves, goggles, and lab coat, when handling the compound. It is essential to work in a well-ventilated area and avoid breathing in vapors or mists. In case of accidental exposure, it is important to seek medical advice immediately and provide the relevant information about the substance to healthcare professionals.
🔬 Potential Research Directions
Research on N,N-Dimethylaniline N-oxide may focus on its reactivity and role as a versatile intermediate in organic synthesis processes. Understanding its reactions with various reagents can provide insights into its potential applications in pharmaceuticals, agrochemicals, and materials science.
Further investigations into the physicochemical properties of N,N-Dimethylaniline N-oxide may shed light on its behavior in different solvents and under varying conditions. This can aid in optimizing its synthesis and purification methods, as well as in determining its stability and storage requirements.
Exploring the biological activity of N,N-Dimethylaniline N-oxide and its possible interactions with biological systems could lead to the development of new drugs or therapies. Studies on its toxicological properties and environmental impact may also be worthwhile areas of research in order to ensure its safe handling and disposal.
🧪 Related Compounds
One similar compound to N,N-Dimethylaniline N-oxide is N-Methyl-N’-methylaniline N-oxide. This compound possesses a similar molecular structure to N,N-Dimethylaniline N-oxide, with the only difference being the substitution of one methyl group with an amino group. This results in a slight variation in the physical and chemical properties of the compound compared to N,N-Dimethylaniline N-oxide.
Another related compound is N,N-Dimethyl-p-toluidine N-oxide. This compound differs from N,N-Dimethylaniline N-oxide by having a methyl group attached to the para position of the aromatic ring. The presence of this methyl group alters the steric hindrance and electronic properties of the compound, leading to differences in reactivity and potential applications in various chemical processes.
A third compound with a similar structure is N,N-Dimethyl-p-anisidine N-oxide. This compound is structurally analogous to N,N-Dimethylaniline N-oxide, except for the presence of a methoxy group in the para position of the aromatic ring. The substitution of the methoxy group for a methyl group introduces variations in the compound’s properties, such as solubility, stability, and reactivity, making it a distinct compound with its own set of potential uses.
