Naphthalene-1,2-Diol

Naphthalene-1,2-Diol, a chemical compound commonly known as alpha-naphthol, holds significance in everyday life due to its diverse applications in various industries. In the realm of consumer products, it is utilized in the manufacturing of dyes, perfumes, and pharmaceuticals. Furthermore, it plays a pivotal role in the production of antioxidants, corrosion inhibitors, and polymerization agents. Its versatility and widespread use underscore its importance in both industrial and everyday contexts.

Table of Contents:

💡 Commercial Applications

Naphthalene-1,2-Diol, also known as α-naphthol, finds several commercial and industrial applications. It is commonly used in the production of dyes, pigments, and antioxidants. Additionally, it is utilized as a raw material in the manufacturing of pharmaceuticals and pesticides. Its chemical properties make it a useful component in the synthesis of various organic compounds.

Moreover, Naphthalene-1,2-Diol has significant drug and medication applications. It is employed in the pharmaceutical industry for the production of antiseptics, disinfectants, and anti-infective agents. Its antibacterial and antifungal properties make it a valuable ingredient in medicinal products. Additionally, it is used in the formulation of topical medications for treating skin conditions such as acne and eczema.

In conclusion, Naphthalene-1,2-Diol plays a crucial role in both commercial and industrial sectors, as well as in the pharmaceutical and medical fields. Its versatile properties make it a valuable compound for a wide range of applications, contributing to the advancement of various industries.

⚗️ Chemical & Physical Properties

Naphthalene-1,2-Diol appears as white crystalline solid with a faint, pleasant odor. It is commonly used in the production of dyes and pharmaceuticals due to its unique properties.

Naphthalene-1,2-Diol has a molar mass of approximately 144.15 g/mol and a density of about 1.28 g/cm³. This places it in the range of molar masses and densities of common household items like sugar and salt.

The melting point of Naphthalene-1,2-Diol is around 122-125°C, while its boiling point is approximately 310-313°C. These values are higher compared to common household items like ice and water, which have lower melting and boiling points.

Naphthalene-1,2-Diol is slightly soluble in water and has a low viscosity. Its solubility and viscosity are similar to common household items like vinegar and rubbing alcohol.

🏭 Production & Procurement

Naphthalene-1,2-Diol, also known as 1,2-dihydroxynaphthalene, is typically produced through the selective oxidation of naphthalene. This process involves the use of chemical reagents and catalysts to convert naphthalene into Naphthalene-1,2-Diol, which is an important building block in the synthesis of various chemicals and pharmaceuticals.

The procurement of Naphthalene-1,2-Diol involves sourcing the raw materials needed for its production, such as naphthalene and oxidizing agents. These materials are often obtained from chemical suppliers and manufacturers who specialize in providing high-quality ingredients for the synthesis of organic compounds. Once the Naphthalene-1,2-Diol is produced, it can be transported in sealed containers to prevent contamination and degradation during transit.

Transporting Naphthalene-1,2-Diol requires careful handling and compliance with regulations governing the transportation of hazardous chemicals. Due to its potential hazards and reactivity, Naphthalene-1,2-Diol is typically transported in labeled containers that meet safety standards for the storage and transport of hazardous materials. Proper labeling, packaging, and handling procedures are essential to ensure the safe and efficient transport of Naphthalene-1,2-Diol to its destination.

⚠️ Safety Considerations

Safety considerations for Naphthalene-1,2-Diol primarily revolve around its potential toxicity and irritant properties. It is essential to handle this compound with care and use appropriate personal protective equipment, such as gloves and goggles, when working with it. Proper ventilation is also crucial to prevent inhalation of vapors. In addition, it is important to store Naphthalene-1,2-Diol in a cool, dry place away from sources of heat or ignition to avoid the risk of fire.

The pharmacology of Naphthalene-1,2-Diol involves its ability to act as an antioxidant and free radical scavenger. This compound is known for its potential therapeutic properties, such as anti-inflammatory and anti-cancer effects. However, its exact mechanism of action and pharmacokinetics still require further research to fully understand its potential benefits and risks when used in pharmaceutical applications.

Hazard statements for Naphthalene-1,2-Diol include its classification as a skin irritant and eye irritant. It may cause sensitization by skin contact and is harmful if swallowed or inhaled. Prolonged or repeated exposure to this compound may result in adverse health effects. It is essential to follow proper handling and storage procedures to minimize the risk of exposure and subsequent hazards.

Precautionary statements for Naphthalene-1,2-Diol include avoiding direct contact with skin and eyes and using appropriate protective equipment, such as gloves and goggles. In case of ingestion, seek medical advice immediately and do not induce vomiting. If exposed to vapors or fumes, move to fresh air and seek medical attention if symptoms persist. It is crucial to handle this compound with caution and follow recommended safety guidelines to prevent any potential health risks.

🔬 Potential Research Directions

Potential research directions for Naphthalene-1,2-Diol may include studying its role in various biological processes, such as its potential as an antioxidant or its interactions with enzymes and receptors in the body.

Researchers may also investigate the potential therapeutic applications of Naphthalene-1,2-Diol in treating conditions such as inflammation, cancer, or neurological disorders, exploring its mechanisms of action and efficacy in preclinical and clinical studies.

Furthermore, exploring the environmental impact of Naphthalene-1,2-Diol and its byproducts, as well as developing sustainable synthesis methods to minimize its production and release into the environment, could be an important area of research in the future.

One compound that bears structural similarity to Naphthalene-1,2-Diol is Naphthalene-1,4-Diol. This compound also contains two hydroxyl groups attached at the 1st and 4th positions of the naphthalene ring. Naphthalene-1,4-Diol exhibits similar physiological and chemical properties to Naphthalene-1,2-Diol due to their shared functional groups.

Another compound with a comparable molecular structure to Naphthalene-1,2-Diol is Naphthalene-2,3-Diol. In this compound, the hydroxyl groups are situated at the 2nd and 3rd positions of the naphthalene ring. Naphthalene-2,3-Diol shares a similar framework and reactivity with Naphthalene-1,2-Diol, making them analogs in terms of chemical behavior and properties.

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