N1-acetylspermine

N1-acetylspermine, a naturally occurring compound found in the human body, plays a crucial role in various physiological processes. It is involved in cell growth, cell differentiation, and DNA synthesis, making it an essential component for the proper functioning of the body. Additionally, N1-acetylspermine has been linked to various health conditions, including cancer and neurological disorders. Understanding the role of N1-acetylspermine in everyday life can provide valuable insights into the maintenance of overall health and well-being.

Table of Contents:

💡 Commercial Applications

N1-acetylspermine, a polyamine compound, has various commercial and industrial applications. It is used in the production of cosmetics and personal care products as a fragrance fixative and stabilizer. Additionally, it is utilized in the manufacturing of specialty chemicals and in the food industry as a food additive.

In the realm of drug and medication applications, N1-acetylspermine has been studied for its potential therapeutic effects. Research suggests it may have anti-inflammatory properties and could be used in the development of new drugs for treating inflammatory conditions. Furthermore, there is ongoing investigation into its role in cancer therapy, as it may have anti-tumor effects that could be beneficial in the treatment of certain types of cancer.

⚗️ Chemical & Physical Properties

N1-acetylspermine is a white solid with no distinct odor. It is a crystalline substance that is typically found in a powder form.

The molar mass of N1-acetylspermine is approximately 246.31 g/mol, and its density is around 1.004 g/cm3. This places it in the range of common household items such as baking soda in terms of molar mass and density.

N1-acetylspermine has a melting point of approximately 122-123°C and a boiling point of around 432.6°C. In comparison to common household items, this places it in the range of substances like sugar in terms of melting point and boiling point.

N1-acetylspermine is sparingly soluble in water and exhibits low viscosity. This places it in the range of substances like table salt in terms of solubility and viscosity in water.

🏭 Production & Procurement

N1-acetylspermine is typically produced through chemical synthesis in laboratory settings. This involves the reaction of spermine with acetic anhydride to form the desired compound. The process requires precise control of reaction conditions to ensure optimal yield and purity.

N1-acetylspermine can be procured from specialized chemical suppliers that produce and distribute research-grade compounds. It is often available in the form of a white crystalline powder or solution. Once procured, the compound can be transported in sealed containers to prevent degradation or contamination during transit.

The transportation of N1-acetylspermine typically involves the use of secure packaging to ensure safe handling and delivery. It is important to adhere to regulations regarding the shipment of chemical compounds to prevent any potential hazards during transport. Proper labeling and documentation are essential to facilitate the smooth transport of N1-acetylspermine to its intended destination.

⚠️ Safety Considerations

Safety Considerations for N1-acetylspermine:

When handling N1-acetylspermine, it is important to wear appropriate personal protective equipment, such as gloves and goggles, to prevent skin and eye contact with the chemical. The compound should be stored in a cool, dry place away from direct sunlight and sources of ignition to avoid potential hazards. Additionally, N1-acetylspermine should be kept away from incompatible materials and should be handled in a well-ventilated area to prevent exposure to harmful vapors.

Pharmacology of N1-acetylspermine:

N1-acetylspermine is a polyamine metabolite that plays a crucial role in cell growth and proliferation. It is involved in various physiological processes, including cell differentiation, gene expression, and protein synthesis. N1-acetylspermine has been studied for its potential therapeutic applications in cancer treatment and as a biomarker for certain diseases.

Hazard Statements for N1-acetylspermine:

N1-acetylspermine may be harmful if swallowed, inhaled, or absorbed through the skin. It can cause skin and eye irritation upon contact and may have adverse effects on human health if proper precautions are not taken. Exposure to high concentrations of N1-acetylspermine can result in respiratory distress, dizziness, and other toxic effects. It is important to handle this compound with care and follow safety protocols to minimize the risk of harm.

Precautionary Statements for N1-acetylspermine:

When working with N1-acetylspermine, it is advisable to use protective clothing, gloves, and eyewear to prevent skin and eye contact. Avoid breathing in vapors or dust particles and ensure adequate ventilation in the working area. In case of accidental exposure or ingestion, seek medical attention immediately and provide relevant information about the chemical. Proper handling and storage practices should be followed to minimize the risk of hazards associated with N1-acetylspermine.

🔬 Potential Research Directions

Research on N1-acetylspermine, a polyamine derived from spermine, shows promising potential in various areas of biomedical science. Studies suggest that N1-acetylspermine may play a role in regulating cell growth and proliferation, making it a subject of interest in cancer biology research. Additionally, N1-acetylspermine has been implicated in the modulation of immune responses, opening up avenues for investigation into its potential therapeutic applications in autoimmune diseases and inflammatory conditions.

Further research into the molecular mechanisms underlying the function of N1-acetylspermine is warranted to elucidate its precise role in cellular processes. Understanding how N1-acetylspermine interacts with other molecules and proteins within the cell can provide valuable insights into its biological functions and potential targets for pharmacological interventions. Exploring the effects of N1-acetylspermine on gene expression and signaling pathways may also reveal new opportunities for drug development and personalized medicine strategies.

Moreover, the investigation of N1-acetylspermine as a biomarker for certain diseases or conditions holds promise for diagnostic and prognostic purposes. By studying the levels of N1-acetylspermine in biological samples, researchers may be able to identify patterns or correlations with specific health outcomes. This line of research could lead to the development of novel diagnostic tools and strategies for monitoring disease progression and response to treatment.

One similar compound to N1-acetylspermine based upon molecular structure is N1-acetylspermidine. This compound is derived from spermidine through the addition of an acetyl group at the nitrogen atom. Like N1-acetylspermine, N1-acetylspermidine is involved in various biological processes, such as cell growth and differentiation.

Another compound with a similar molecular structure to N1-acetylspermine is N1-acetylcadaverine. N1-acetylcadaverine is formed by the acetylation of cadaverine, a polyamine found in living tissue. Similar to N1-acetylspermine, N1-acetylcadaverine plays a role in cell proliferation and cell cycle regulation.

Additionally, N1-acetylputrescine is a compound closely related in structure to N1-acetylspermine. N1-acetylputrescine is produced by the acetylation of putrescine, another polyamine found in cells. This compound, like N1-acetylspermine, is involved in the regulation of gene expression and cell growth.

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