N-Methylnicotinic acid, a derivative of niacin, plays a crucial role in various biological processes within the human body. It is involved in energy production, DNA repair, and cell communication, making it essential for overall health and functioning. While not directly consumed in everyday life, the presence of N-Methylnicotinic acid in the body highlights the importance of maintaining a balanced diet rich in niacin-rich foods such as poultry, fish, and whole grains. Its significance underscores the interconnectedness of nutrition and well-being in our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-Methylnicotinic acid, also known as MNA, has several commercial and industrial applications. It is used in the production of pesticides, particularly as a raw material for the synthesis of neonicotinoid insecticides. These insecticides are widely used in agriculture to control pests and protect crops.
In addition to its use in pesticides, N-Methylnicotinic acid is also employed in the manufacturing of pharmaceuticals and dyes. It serves as a key intermediate in the synthesis of various drugs and medications, as well as in the production of organic compounds for the dye industry. Its versatile properties make it a valuable ingredient in the chemical industry.
Furthermore, N-Methylnicotinic acid has shown potential in the field of medical research. Studies have indicated that it may have therapeutic properties, such as anti-inflammatory and anti-cancer effects. Researchers are exploring its potential applications in the development of new drugs for various medical conditions, further highlighting its importance in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
N-Methylnicotinic acid appears as a white crystalline solid with no distinct odor present. It is a chemical compound that is primarily used in pharmaceutical research and production.
The molar mass of N-Methylnicotinic acid is approximately 167.17 g/mol, and its density is around 1.31 g/cm^3. In comparison to common household items, it has a higher molar mass than water (18.02 g/mol) and a higher density than olive oil (0.92 g/cm^3).
The melting point of N-Methylnicotinic acid ranges from 185-187°C, while its boiling point is approximately 310-314°C. Compared to common household items, it has a higher melting point than table salt (801°C) and a higher boiling point than vinegar (100°C).
N-Methylnicotinic acid is sparingly soluble in water and has a low viscosity. In comparison to common household items, it is less soluble in water than table sugar and has a lower viscosity than honey.
🏭 Production & Procurement
N-Methylnicotinic acid is typically produced through a multistep chemical synthesis process. The starting material is usually nicotinic acid, which is then methylated using a methylating agent such as dimethyl sulfate or methyl iodide. The reaction is typically carried out under controlled conditions to ensure high yield and purity of the final product.
Once N-Methylnicotinic acid is produced, it can be procured from chemical suppliers or pharmaceutical companies that specialize in the production of fine chemicals. The compound is commonly available in both research grade and commercial grade purity levels. Orders can be placed online or through distributors, and the compound can be shipped in various forms such as powder, crystals, or solutions depending on the customer’s requirements.
N-Methylnicotinic acid is typically transported in sealed containers or drums to prevent contamination or degradation during transit. It is important to handle the compound with care and follow established safety guidelines for handling and storage. Proper labeling and documentation are also essential to ensure compliance with regulatory requirements during transportation and delivery to the end user.
⚠️ Safety Considerations
Safety considerations for N-Methylnicotinic acid should be carefully observed due to its potential hazards. When handling this compound, it is essential to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat to prevent direct contact with the skin, eyes, or clothing. Additionally, N-Methylnicotinic acid should be stored in a cool, dry, well-ventilated area away from heat and incompatible materials to prevent accidental fires or reactions.
The pharmacology of N-Methylnicotinic acid involves its role as a synthetic intermediate in the production of pharmaceuticals and organic compounds. This compound is primarily used in the synthesis of drugs and as a precursor for various chemical reactions. N-Methylnicotinic acid may exhibit certain pharmacological properties due to its chemical structure, but further research is needed to fully understand its biological effects and potential applications in the field of medicine.
Hazard statements for N-Methylnicotinic acid include the potential for skin and eye irritation, as well as respiratory and allergic reactions upon exposure. This compound may cause irritation to the skin and eyes upon contact, leading to redness, burning, or itching sensations. Inhalation of N-Methylnicotinic acid vapors or dust particles may also result in respiratory irritation, coughing, or shortness of breath. It is important to handle this compound with caution and follow proper safety protocols to minimize the risk of adverse health effects.
Precautionary statements for N-Methylnicotinic acid advise users to avoid direct skin and eye contact, as well as inhalation of vapors or dust particles. It is recommended to work with this compound in a fume hood or well-ventilated area to prevent exposure to potentially harmful fumes. In case of accidental contact, immediate washing of the affected area with soap and water is advised, and medical attention should be sought if irritation persists. Proper disposal methods should also be followed to prevent environmental contamination and ensure safe handling of N-Methylnicotinic acid.
🔬 Potential Research Directions
One potential research direction for N-Methylnicotinic acid lies in exploring its pharmacological properties and potential therapeutic applications. Studies could investigate its role in various physiological processes and its interactions with different biological targets to uncover its potential as a drug candidate.
Another avenue of research could focus on the synthesis and derivatization of N-Methylnicotinic acid to generate novel analogs with improved pharmacokinetic and pharmacodynamic profiles. By modifying its chemical structure, researchers may be able to enhance its efficacy, reduce toxicity, or alter its mode of action, leading to the development of more potent and selective compounds.
Furthermore, investigating the metabolic fate of N-Methylnicotinic acid in the body could provide valuable insights into its absorption, distribution, metabolism, and excretion. Understanding its biotransformation pathways and identifying its major metabolites could aid in determining its overall safety profile and potential drug interactions, informing future preclinical and clinical studies.
🧪 Related Compounds
One similar compound to N-Methylnicotinic acid based upon molecular structure is N,N-Dimethylnicotinic acid. In this compound, there are two methyl groups attached to the nitrogen atom of the nicotinic acid molecule. This results in a slightly different chemical structure compared to N-Methylnicotinic acid, but they share similarities in terms of having methyl groups attached to the nitrogen atom.
Another similar compound is N-Ethyl-Nicotinic acid, where an ethyl group is attached to the nitrogen atom of the nicotinic acid molecule. This compound differs from N-Methylnicotinic acid in the type of alkyl group attached to the nitrogen atom, but they both exhibit similar chemical properties due to the presence of an alkyl group on the nitrogen atom.
Additionally, N-Isopropylnicotinic acid is a compound similar to N-Methylnicotinic acid in terms of molecular structure. In this compound, an isopropyl group is attached to the nitrogen atom of the nicotinic acid molecule. Despite the different alkyl group attached to the nitrogen atom, N-Isopropylnicotinic acid shares similarities with N-Methylnicotinic acid in terms of their structural characteristics and chemical properties.
