N-Methylaniline, a derivative of aniline, holds relevance to everyday life due to its diverse applications across various industries. This compound is commonly used in the production of dyes, pharmaceuticals, and pesticides, highlighting its importance in the manufacturing sector. Additionally, N-Methylaniline is utilized in the synthesis of certain polymers and as a chemical intermediate in the production of other important substances. Overall, the significance of N-Methylaniline lies in its foundational role in the creation of a wide range of consumer products that are integral to modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-Methylaniline, also known as NMA, finds several commercial and industrial applications due to its unique properties. It is commonly used as a precursor in the production of dyes, pigments, and pharmaceuticals. Additionally, NMA is utilized in the manufacturing of antioxidants, rubber chemicals, and agricultural chemicals.
In the realm of drug and medication applications, N-Methylaniline is utilized in the synthesis of various pharmaceutical compounds. It is often employed as an intermediate in the production of analgesics, antipyretics, and antimalarial drugs. Additionally, NMA serves as a building block for the creation of certain anti-inflammatory medications used to treat a variety of medical conditions.
⚗️ Chemical & Physical Properties
N-Methylaniline appears as a colorless to pale yellow liquid with a characteristic amine odor. It is commonly used in the synthesis of dyes and pharmaceuticals due to its chemical properties.
N-Methylaniline has a molar mass of approximately 121.18 g/mol and a density of about 0.982 g/cm3. This places it in the range of molar masses and densities of common household items such as water and ethanol.
The melting point of N-Methylaniline is around -57°C, while the boiling point is approximately 193-195°C. These values are higher compared to common household items like water and isopropyl alcohol in terms of melting and boiling points.
N-Methylaniline is slightly soluble in water and exhibits a low viscosity. This is in contrast to common household items such as salt and sugar which are highly soluble in water and have higher viscosities.
🏭 Production & Procurement
N-Methylaniline is typically produced through a process known as methylation of aniline using methyl iodide or dimethyl sulfate as the methylating agent. This reaction yields N-Methylaniline as the main product along with some minor byproducts. The resulting N-Methylaniline can then be purified through techniques such as distillation or crystallization.
N-Methylaniline can be procured from chemical suppliers or manufacturers who specialize in producing aromatic amines. It is commonly available in varying purities, typically ranging from industrial-grade to high purity for research and laboratory use. The compound is often transported in sealed containers or drums to prevent contamination or leakage during transit.
The transportation of N-Methylaniline is subject to regulations set forth by governing bodies, such as the Department of Transportation, to ensure safe handling and storage. Proper labeling and documentation are necessary for the shipment of N-Methylaniline, and it may require appropriate permits or licenses depending on the quantity being transported. Storage of N-Methylaniline should be done in a well-ventilated area away from heat sources or incompatible materials to prevent any potential hazards.
⚠️ Safety Considerations
Safety Considerations for N-Methylaniline:
N-Methylaniline is a hazardous chemical that requires careful handling to avoid potential health risks. It is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat when working with N-Methylaniline to prevent skin and eye contact. In addition, this chemical should only be used in a well-ventilated area to minimize inhalation exposure.
N-Methylaniline should be stored in a cool, dry place away from incompatible substances such as strong oxidizing agents or acids to prevent chemical reactions that may lead to accidents. It is also important to label containers of N-Methylaniline clearly with the appropriate hazard warnings to ensure that individuals are aware of the potential risks associated with this chemical. Proper disposal methods should be followed to prevent environmental contamination.
Pharmacology of N-Methylaniline:
N-Methylaniline is a compound that is commonly used in the synthesis of various pharmaceuticals and dyes. It is known to have analgesic properties and is sometimes used as an intermediate in the production of pain relief medications. The pharmacological activity of N-Methylaniline is due to its ability to interact with certain receptors in the central nervous system, leading to pain relief effects.
Hazard Statements for N-Methylaniline:
Hazard statements associated with N-Methylaniline include “Harmful if swallowed” and “Causes skin irritation.” This chemical is also classified as a skin sensitizer and may cause allergic reactions upon repeated exposure. In addition, N-Methylaniline is toxic to aquatic life and may have long-lasting effects on the environment if not handled properly.
Precautionary Statements for N-Methylaniline:
Precautionary statements for N-Methylaniline include “Avoid breathing dust/fume/gas/mist/vapors/spray,” “Wash hands thoroughly after handling,” and “Do not eat, drink, or smoke when using this product.” It is important to handle N-Methylaniline with care and follow proper safety protocols to minimize the risk of exposure. In case of accidental exposure, it is recommended to seek medical attention immediately and provide relevant information about the chemical involved.
🔬 Potential Research Directions
Research on N-Methylaniline has the potential to focus on its industrial applications, particularly in the synthesis of dyes and pharmaceuticals. This compound’s unique chemical properties make it a valuable starting material for various organic reactions.
Further investigations may explore the environmental impact of N-Methylaniline and its derivatives. Understanding its biodegradation pathways and toxicity can inform strategies for safe handling and disposal in industrial settings.
Studies on the biological activity of N-Methylaniline could also yield insights into its potential uses as a drug candidate. Screening its pharmacological properties may reveal new therapeutic targets and drug delivery mechanisms.
🧪 Related Compounds
One similar compound to N-Methylaniline based on molecular structure is N,N-Dimethylaniline. This compound has the chemical formula C8H11N and consists of a benzene ring with two methyl groups attached to the nitrogen atom. N,N-Dimethylaniline is commonly used as a precursor in the synthesis of various chemicals and dyes due to its reactivity and stability.
Another compound with a similar molecular structure to N-Methylaniline is N-Ethylaniline. This compound has the chemical formula C8H11N and features a benzene ring with an ethyl group attached to the nitrogen atom. N-Ethylaniline is often used as a solvent in chemical reactions and as an intermediate in the production of pharmaceuticals and agrochemicals.
Additionally, N-Propylaniline is a compound that shares a molecular structure with N-Methylaniline. With the chemical formula C9H13N, N-Propylaniline contains a benzene ring with a propyl group attached to the nitrogen atom. This compound is used in the production of rubber antioxidants and pharmaceutical intermediates due to its unique chemical properties.
