N-Acetylimidazole is a chemical compound that is primarily utilized in various industries including pharmaceuticals, agriculture, and research. This compound is commonly used in organic synthesis as a reagent for acetylation reactions, making it a crucial tool for the production of pharmaceutical drugs, pesticides, and other chemical compounds. Additionally, N-Acetylimidazole plays a key role in biochemical research as a versatile and efficient coupling agent in peptide synthesis. Overall, N-Acetylimidazole’s significance lies in its wide-ranging applications in these industries and its contributions to advancements in science and technology.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-Acetylimidazole has various commercial and industrial applications, primarily as a chemical intermediate in the synthesis of pharmaceuticals, pesticides, and dyes. It is commonly used as a reagent in organic chemistry reactions due to its ability to acylate nucleophiles, making it a versatile compound in the manufacturing of various products.
In the realm of drug and medication applications, N-Acetylimidazole is utilized as a key ingredient in the synthesis of certain pharmaceutical drugs. Its acetyl group acts as a protecting group in organic synthesis, allowing for specific reactions to take place without interfering with other functional groups present in the molecule. This makes it a valuable compound in the development of new medications and treatments for various medical conditions.
⚗️ Chemical & Physical Properties
N-Acetylimidazole is a white crystalline solid with a faint odor. It is generally described as a mild-smelling compound, which may be favorable in certain applications.
N-Acetylimidazole has a molar mass of 126.14 g/mol and a density of 1.16 g/cm³. Compared to common food items such as sugar (molar mass of 342.3 g/mol, density of 1.59 g/cm³) and salt (molar mass of 58.44 g/mol, density of 2.17 g/cm³), N-Acetylimidazole has a lower molar mass and density.
The melting point of N-Acetylimidazole is approximately 45°C, while the boiling point is around 180°C. These values are lower than those of common food items such as butter (melting point around 32°C, boiling point around 100°C) and olive oil (melting point around -6°C, boiling point around 190-240°C).
N-Acetylimidazole is sparingly soluble in water and exhibits low viscosity. In comparison, common food items like sugar and salt are highly soluble in water and do not have significant viscosity.
🏭 Production & Procurement
N-Acetylimidazole is commonly produced through the acetylation of imidazole with acetic anhydride in the presence of a base catalyst. This reaction typically takes place under controlled conditions to ensure both the consistency and purity of the final product. The resulting N-Acetylimidazole is then typically purified through methods such as column chromatography to remove any impurities.
Procuring N-Acetylimidazole can be done through various chemical suppliers who specialize in providing research chemicals and intermediates to laboratories and industrial facilities. The compound is often available in different quantities, ranging from small research-scale amounts to larger industrial-scale quantities. N-Acetylimidazole can be transported in sealed containers to prevent any contamination or degradation during transit. Special care should be taken to ensure that the compound is stored and handled properly to maintain its stability and purity.
⚠️ Safety Considerations
Safety considerations for N-Acetylimidazole are paramount due to its potential hazards. This chemical compound is known to be flammable and may cause skin irritation and serious eye damage upon contact. Inhaling its vapors may also lead to respiratory irritation and dizziness, making proper ventilation essential when handling N-Acetylimidazole. Additionally, it is important to use personal protective equipment such as gloves, goggles, and lab coats to minimize the risk of exposure.
Hazard statements for N-Acetylimidazole include “causes skin irritation,” “causes serious eye damage,” and “may cause respiratory irritation.” These statements serve as a warning to individuals working with this chemical compound to exercise caution and follow proper safety protocols. It is imperative to handle N-Acetylimidazole with care, avoiding direct contact with skin or eyes, and ensuring adequate ventilation in the work area to prevent inhalation of its vapors.
Precautionary statements for N-Acetylimidazole recommend storing the chemical in a well-ventilated place and keeping it tightly closed when not in use to prevent exposure. It is advised to wear protective gloves, clothing, eye protection, and face protection when handling N-Acetylimidazole to minimize the risk of skin, eye, or respiratory irritation. In case of skin or eye contact, immediate medical attention is required, along with rinsing affected areas with water for several minutes.
🔬 Potential Research Directions
Potential research directions of N-Acetylimidazole include studying its potential as a versatile intermediate in organic synthesis due to its ability to undergo various reactions to form important chemical compounds.
Researchers may also explore the use of N-Acetylimidazole in the pharmaceutical industry, as it has shown promising antimicrobial properties and has the potential to be developed into new drugs to combat various diseases.
Another area of interest could be investigating the role of N-Acetylimidazole in materials science, as it may have applications in the development of innovative materials with unique properties and enhanced performance characteristics.
🧪 Related Compounds
One similar compound to N-Acetylimidazole is N-Acetylphenolsulfonamide. This compound also contains an acetyl group attached to a nitrogen atom, similar to N-Acetylimidazole. The structure of N-Acetylphenolsulfonamide includes a phenol ring, which differentiates it from N-Acetylimidazole.
Another compound with a similar molecular structure to N-Acetylimidazole is N-Acetylthiourea. This compound possesses an acetyl group attached to a nitrogen atom, much like N-Acetylimidazole. However, N-Acetylthiourea contains a thiourea functional group, distinguishing it from N-Acetylimidazole.
N-Acetylpyrrole is yet another compound that bears resemblance to N-Acetylimidazole in terms of molecular structure. Both compounds feature an acetyl group attached to a nitrogen atom. However, N-Acetylpyrrole includes a pyrrole ring, setting it apart from N-Acetylimidazole.
