N-(4-Nitrophenyl)acetamide, a compound commonly employed in scientific research and chemical synthesis, may not have direct relevance to everyday life for the average consumer. However, its significance lies in its potential applications in pharmaceuticals, agricultural chemicals, and material science. Through further study and comprehension of this compound, researchers may uncover valuable insights that could ultimately contribute to the development of practical products and technologies that impact daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-(4-Nitrophenyl)acetamide, commonly known as NNPA, is primarily used in commercial and industrial applications. It is utilized in the synthesis of pharmaceuticals, as a reagent in organic chemistry, and as a precursor in various chemical reactions.
Furthermore, NNPA is also used in the production of dyes, pigments, and fine chemicals. Its versatile nature and chemical properties make it a valuable compound in the manufacturing industries for the development of various products.
In terms of drug and medication applications, NNPA is not commonly used. However, it has been studied for its potential pharmaceutical properties and may have future applications in the field of medicine. Its unique structure and chemical composition make it a promising candidate for further research and development in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
N-(4-Nitrophenyl)acetamide appears as a white crystalline solid with no distinct odor. It is generally odorless in its pure form.
N-(4-Nitrophenyl)acetamide has a molar mass of approximately 197.18 g/mol and a density of about 1.357 g/cm³. Compared to common food items, such as sugars and salts, N-(4-Nitrophenyl)acetamide has a higher molar mass and density.
The melting point of N-(4-Nitrophenyl)acetamide is around 164-166°C, while the boiling point is approximately 457.5°C. In comparison to common food items, N-(4-Nitrophenyl)acetamide has higher melting and boiling points.
N-(4-Nitrophenyl)acetamide is sparingly soluble in water and has a low viscosity. When compared to common food items like sugar and salt, N-(4-Nitrophenyl)acetamide has lower solubility in water and lower viscosity.
🏭 Production & Procurement
N-(4-Nitrophenyl)acetamide is typically produced through the reaction of 4-nitroaniline with acetic anhydride in the presence of a catalyst. This process results in the formation of the desired product, which can then be purified through various techniques such as recrystallization or column chromatography.
The procurement of N-(4-Nitrophenyl)acetamide can be achieved through various chemical suppliers or manufacturers that specialize in providing fine chemicals. Once procured, the compound can be transported in solid form in sealed containers to prevent degradation or contamination during transit. It is important to follow proper handling and storage procedures to maintain the integrity of the compound.
Alternatively, N-(4-Nitrophenyl)acetamide can also be synthesized in a laboratory setting by researchers or chemists who have the necessary expertise and equipment. This allows for greater control over the production process and can ensure the purity and quality of the final product. Proper safety measures and protocols should be followed during the synthesis and handling of the compound to prevent accidents or exposure to harmful substances.
⚠️ Safety Considerations
Safety considerations for N-(4-Nitrophenyl)acetamide involve handling the compound with caution due to its potential hazards. It is important to avoid inhalation, ingestion, or skin contact with the substance, as it may cause irritation or damage. Proper eye protection, gloves, and lab coat should be worn when working with N-(4-Nitrophenyl)acetamide to minimize the risk of exposure.
Hazard statements for N-(4-Nitrophenyl)acetamide include warnings about its harmful effects if swallowed, inhaled, or in contact with skin. The compound may cause irritation to the respiratory system, skin, and eyes. It is also labeled as harmful to aquatic life, highlighting the importance of preventing its release into the environment.
Precautionary statements for N-(4-Nitrophenyl)acetamide recommend wearing protective clothing, gloves, and eye/face protection when handling the compound. It is advised to keep the substance away from heat, sparks, open flames, and other sources of ignition. Proper ventilation is necessary to ensure a safe working environment while using N-(4-Nitrophenyl)acetamide.
🔬 Potential Research Directions
One potential research direction for N-(4-Nitrophenyl)acetamide is to investigate its pharmacological properties, such as its potential as a drug candidate for various medical conditions. Studies could focus on its mechanism of action, bioavailability, and potential side effects to assess its viability as a therapeutic agent.
Another avenue of research could be to explore the synthesis of novel derivatives of N-(4-Nitrophenyl)acetamide with improved pharmacological properties. Structural modifications could be made to enhance its efficacy, increase its solubility, or reduce potential toxicity. These studies could lead to the development of analogs with enhanced therapeutic potential.
Furthermore, investigations into the antimicrobial activity of N-(4-Nitrophenyl)acetamide could be of interest. Studies could explore its efficacy against various pathogens, mechanisms of action, and potential use in combating antibiotic-resistant strains. This research could contribute to the development of new antimicrobial agents to address the growing issue of antibiotic resistance.
🧪 Related Compounds
One similar compound to N-(4-Nitrophenyl)acetamide based on its molecular structure is N-(4-Methylphenyl)acetamide. In this compound, the nitro group on the phenyl ring has been replaced with a methyl group. This substitution results in a slightly different electronic and steric environment around the amide group, leading to potential differences in reactivity and physical properties.
Another related compound is N-(4-Chlorophenyl)acetamide, where the nitro group is replaced with a chlorine atom on the phenyl ring. This substitution introduces a different electronic character to the molecule compared to the nitro group, which can impact its chemical behavior. The presence of the chlorine atom can also influence the compound’s solubility and interaction with other molecules.
A further analog is N-(4-Hydroxyphenyl)acetamide, where the nitro group is replaced with a hydroxyl group on the phenyl ring. This substitution introduces a polar functional group, which can alter the compound’s hydrogen bonding capabilities and reactivity compared to N-(4-Nitrophenyl)acetamide. The presence of the hydroxyl group can also impact the compound’s solubility and pharmacological properties.
