N-(4-Hydroxyphenyl)stearamide, also known as ceramide NP, is a lipid molecule that plays a crucial role in maintaining the skin’s barrier function. Its ability to retain moisture and protect against external stressors makes it an essential ingredient in skincare products. By replenishing ceramide levels in the skin, products containing N-(4-Hydroxyphenyl)stearamide help to improve hydration, prevent water loss, and enhance overall skin health. As such, the use of ceramide NP in skincare routines can have a tangible impact on individuals’ everyday lives by promoting skin comfort, resilience, and a healthy appearance.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-(4-Hydroxyphenyl)stearamide, also known as 4-hydroxy-N-stearamoylphenylamine, finds various commercial and industrial applications due to its properties. It is often used as an additive in lubricants and coatings due to its ability to provide protection against wear and corrosion. Additionally, it serves as a stabilizer in plastics and rubber products to enhance their properties and longevity.
In terms of drug and medication applications, N-(4-Hydroxyphenyl)stearamide has shown potential as an ingredient in skincare products. Its antioxidant properties can help protect the skin from environmental stressors and promote overall skin health. Furthermore, studies have suggested its use in topical formulations for its anti-inflammatory and anti-aging effects, making it a promising ingredient in cosmetic and pharmaceutical industries.
⚗️ Chemical & Physical Properties
N-(4-Hydroxyphenyl)stearamide is a white solid that typically appears in a crystalline form. It does not have a distinct odor.
The molar mass of N-(4-Hydroxyphenyl)stearamide is approximately 339.58 g/mol, with a density of about 1.055 g/cm3. Compared to common food items, such as sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm3) and salt (molar mass: 58.44 g/mol, density: 2.16 g/cm3), N-(4-Hydroxyphenyl)stearamide has a lower molar mass and density.
N-(4-Hydroxyphenyl)stearamide has a melting point of around 127-129°C and a boiling point of approximately 520°C. In comparison to common food items like butter (melting point: 32-35°C, boiling point: 200-300°C) and water (melting point: 0°C, boiling point: 100°C), N-(4-Hydroxyphenyl)stearamide has higher melting and boiling points.
N-(4-Hydroxyphenyl)stearamide is insoluble in water and has a high viscosity. In contrast, common food items like sugar and salt are highly soluble in water and have low viscosity.
🏭 Production & Procurement
N-(4-Hydroxyphenyl)stearamide is typically produced through a reaction between 4-hydroxyaniline and stearic acid. This reaction results in the formation of the desired product, N-(4-Hydroxyphenyl)stearamide, which is a white to yellowish powder with a melting point of around 125-128°C.
The procurement of N-(4-Hydroxyphenyl)stearamide involves sourcing the necessary raw materials, including 4-hydroxyaniline and stearic acid, from reputable suppliers. These materials are then used in the synthesis process to produce N-(4-Hydroxyphenyl)stearamide in a controlled laboratory setting. Once the product is obtained, it can be packaged and shipped to customers in suitable containers for safe transportation.
Transportation of N-(4-Hydroxyphenyl)stearamide is typically carried out using standard shipping methods, such as air or sea freight, depending on the quantity and destination of the product. Care must be taken to ensure that the product is securely packaged to prevent any damage or contamination during transit. Upon arrival at its destination, the product can be further processed or used in various industrial applications.
⚠️ Safety Considerations
Safety Considerations for N-(4-Hydroxyphenyl)stearamide:
When handling N-(4-Hydroxyphenyl)stearamide, it is important to use appropriate personal protective equipment, such as gloves and safety goggles, to prevent skin and eye irritation. Furthermore, this compound should be stored in a well-ventilated area away from sources of ignition, as it may pose a fire hazard if exposed to high temperatures.
In the event of accidental ingestion or inhalation of N-(4-Hydroxyphenyl)stearamide, medical attention should be sought immediately. It is essential to follow proper disposal procedures for this compound to prevent environmental contamination. Overall, caution should be exercised when working with N-(4-Hydroxyphenyl)stearamide to minimize any potential risks to health and safety.
Hazard Statements for N-(4-Hydroxyphenyl)stearamide:
N-(4-Hydroxyphenyl)stearamide may cause skin irritation and serious eye damage upon contact. In addition, this compound is harmful if swallowed or inhaled, and may cause respiratory irritation. It is important to handle N-(4-Hydroxyphenyl)stearamide with care and take necessary precautions to avoid exposure to skin, eyes, and respiratory system.
Precautionary Statements for N-(4-Hydroxyphenyl)stearamide:
To prevent skin and eye irritation, wear protective gloves and safety goggles when handling N-(4-Hydroxyphenyl)stearamide. In case of skin contact, immediately wash the affected area with soap and water. If N-(4-Hydroxyphenyl)stearamide gets into eyes, rinse thoroughly with water while keeping eyelids open. Avoid inhaling vapors or dust of this compound, and work in a well-ventilated area to minimize exposure. Store N-(4-Hydroxyphenyl)stearamide in a cool, dry place away from incompatible materials and sources of heat or flame.
🔬 Potential Research Directions
Potential research directions for N-(4-Hydroxyphenyl)stearamide include investigating its biological activities, such as its antioxidant properties and potential anti-inflammatory effects. Studies could focus on elucidating its mechanism of action and exploring its potential use in pharmaceutical applications.
Further research could be directed towards examining the potential interactions of N-(4-Hydroxyphenyl)stearamide with other compounds, both synthetic and natural, to determine any synergistic effects or adverse reactions. This could provide valuable information for the development of combination therapies or novel drug formulations.
Additionally, studies could be conducted to assess the bioavailability and pharmacokinetics of N-(4-Hydroxyphenyl)stearamide in different delivery systems. Understanding its absorption, distribution, metabolism, and excretion is essential for optimizing its therapeutic potential and ensuring its safety in clinical use.
🧪 Related Compounds
One compound similar to N-(4-Hydroxyphenyl)stearamide based on molecular structure is N-(4-Hydroxyphenyl)palmitamide. In this compound, the hydroxyphenyl group is attached to a palmitic acid chain instead of a stearic acid chain, resulting in a slightly different physical and chemical properties.
Another compound with a similar structure is N-(4-Hydroxyphenyl)oleamide. Unlike stearamide, this compound has an oleic acid chain attached to the hydroxyphenyl group. This variation in the fatty acid chain can lead to different solubility and bioavailability properties compared to N-(4-Hydroxyphenyl)stearamide.
N-(4-Hydroxyphenyl)octadecanamide is another compound that shares structural similarities with N-(4-Hydroxyphenyl)stearamide. In this compound, the hydroxyphenyl group is linked to an octadecanoic acid chain, which can affect its interactions with biological systems and its potential applications in various industries.
