N-(2-Phenylethyl)acetamide is a chemical compound that is relevant to everyday life as it is a key ingredient in many perfumes and fragrances. The compound is responsible for providing a floral and slightly fruity scent, making it a popular choice for inclusion in various consumer products such as perfumes, lotions, and candles. Additionally, N-(2-Phenylethyl)acetamide is commonly used as a flavoring agent in food products, adding a pleasant aromatic note to items such as baked goods and confectioneries. Its use in these applications underscores its significance in enhancing sensory experiences and contributing to overall well-being.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-(2-Phenylethyl)acetamide, also known as phenethylacetamide, has various commercial and industrial applications. It is commonly used in the fragrance industry as a raw material for the synthesis of perfumes and fragrances due to its pleasant smell. Additionally, it is utilized in the manufacturing of flavors for food products such as beverages and confectionery.
In the pharmaceutical field, N-(2-Phenylethyl)acetamide has shown potential therapeutic properties and is being researched for various drug and medication applications. It has been investigated for its anti-inflammatory and analgesic effects, making it a candidate for pain relief medications. Furthermore, studies have suggested its possible use in formulations for treating neurological disorders, such as Alzheimer’s disease, due to its neuroprotective properties.
Overall, N-(2-Phenylethyl)acetamide presents a versatile compound with a wide range of commercial, industrial, and potential pharmaceutical applications. Its unique properties make it a valuable component in various industries, from fragrances to pharmaceuticals, highlighting its significance in different sectors.
⚗️ Chemical & Physical Properties
N-(2-Phenylethyl)acetamide is a white, crystalline solid with a faint odor. Due to its aromatic component, it may possess a slight sweet or floral scent. The substance is typically odorless when in pure form.
The molar mass of N-(2-Phenylethyl)acetamide is approximately 165.21 g/mol, with a density of around 1.08 g/cm³. Comparatively, common food items such as sugar and salt have lower molar masses and densities, making N-(2-Phenylethyl)acetamide denser than these food ingredients.
N-(2-Phenylethyl)acetamide has a melting point of around 98-100°C and a boiling point of approximately 292-294°C. This is notably higher compared to common food items like butter and chocolate, which melt at lower temperatures and boil at significantly lower temperatures.
N-(2-Phenylethyl)acetamide has limited solubility in water, but it is more soluble in organic solvents. It tends to exhibit low viscosity in solution. This contrasts with common food items like sugar and salt, which are highly soluble in water and may have a higher viscosity when dissolved.
🏭 Production & Procurement
N-(2-Phenylethyl)acetamide, also known as phenylethylacetamide, is typically produced through a multi-step chemical synthesis process. The most common method involves the reaction between phenethylamine and acetic anhydride in the presence of a catalyst, such as lithium aluminum hydride, to yield the desired product.
Once produced, N-(2-Phenylethyl)acetamide can be procured from chemical suppliers or pharmaceutical companies that specialize in fine chemicals. It is typically available in solid form and can be transported in sealed containers to prevent moisture or contamination.
When procuring N-(2-Phenylethyl)acetamide, it is essential to ensure that the material is stored in a cool, dry place away from direct sunlight and sources of heat. Additionally, proper labeling and documentation should accompany the shipment to ensure safe handling and regulatory compliance during transportation.
⚠️ Safety Considerations
Safety considerations for N-(2-Phenylethyl)acetamide include proper storage, handling, and disposal. It is important to keep the compound in a cool, dry place away from direct sunlight, sources of ignition, and incompatible materials. When handling the compound, it is recommended to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. In case of accidental exposure, it is important to wash the affected area thoroughly with soap and water and seek medical attention if necessary.
Hazard statements for N-(2-Phenylethyl)acetamide include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate that the compound has the potential to irritate the skin and eyes upon contact. It is important to avoid direct skin and eye contact with the compound and to wash skin thoroughly if contact occurs. Protective measures such as gloves and goggles should be worn when handling N-(2-Phenylethyl)acetamide to minimize the risk of skin and eye irritation.
Precautionary statements for N-(2-Phenylethyl)acetamide include “Wash hands thoroughly after handling” and “Wear protective gloves/eye protection/face protection.” These statements emphasize the importance of practicing good hygiene and using appropriate protective equipment when working with the compound. It is important to follow standard laboratory safety procedures and guidelines when handling N-(2-Phenylethyl)acetamide to minimize the risk of exposure and potential harm.
🔬 Potential Research Directions
Potential research directions for N-(2-phenylethyl)acetamide include exploring its pharmacological properties and potential therapeutic applications. Researchers may investigate its activity as an analgesic or anti-inflammatory agent, as well as its potential for treating neurological disorders.
Further studies could focus on the mode of action of N-(2-phenylethyl)acetamide at the molecular level, elucidating its interactions with specific receptors or enzymes. This could provide valuable insights into its pharmacokinetics and pharmacodynamics, ultimately informing the development of more effective derivatives or analogs.
Additionally, research may be conducted to assess the safety profile of N-(2-phenylethyl)acetamide, including its potential for adverse effects or toxicity. Preclinical studies could explore its effects on various organ systems and cellular pathways, helping to guide future clinical trials and regulatory approval processes.
🧪 Related Compounds
One similar compound to N-(2-Phenylethyl)acetamide is N-(2-Methylphenylethyl)acetamide. This compound has a similar molecular structure to N-(2-Phenylethyl)acetamide, with the only difference being the presence of a methyl group on the phenyl ring. This slight structural variation may affect the compound’s properties and behavior.
Another related compound is N-(3-Phenylethyl)acetamide. This compound also has a phenyl ring attached to an ethyl group, similar to N-(2-Phenylethyl)acetamide. However, in this compound, the phenyl ring is attached to the third carbon atom of the ethyl group, providing a slightly different spatial arrangement and potentially different chemical properties.
N-(4-Phenylethyl)acetamide is yet another compound that bears resemblance to N-(2-Phenylethyl)acetamide. In this compound, the phenyl ring is attached to the fourth carbon atom of the ethyl group, leading to a distinct molecular structure compared to N-(2-Phenylethyl)acetamide. The position of the phenyl group can impact the compound’s reactivity and biological activity.
