Indole-3-acetamide, a chemical compound derived from indole, holds significance in various industries such as pharmaceuticals, agriculture, and biochemical research. In pharmaceuticals, it is being studied for its potential anti-inflammatory and anti-cancer properties. In agriculture, it is being explored for its potential use as a plant growth regulator. Moreover, in biochemical research, it serves as a valuable tool for studying the biological activities of indole compounds. Ultimately, the relevance of Indole-3-acetamide lies in its potential to contribute to advancements in healthcare, agriculture, and scientific understanding.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Indole-3-acetamide, also known as IAAc, has various commercial and industrial applications. This compound is commonly used in the production of plant growth regulators and hormones due to its ability to promote plant growth and root development. In addition, Indole-3-acetamide is utilized in the manufacturing of pharmaceuticals, perfumes, and agrochemicals.
In terms of drug and medication applications, Indole-3-acetamide has shown potential as a therapeutic agent for various medical conditions. This compound has been studied for its anti-inflammatory and anti-tumor properties, making it a promising candidate for the development of novel medications. Additionally, Indole-3-acetamide has been explored for its potential use in treating neurological disorders and metabolic diseases, showcasing its versatility in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
Indole-3-acetamide is a white crystalline solid with a slight odor that is reminiscent of flowers. Its appearance can vary depending on purity levels.
With a molar mass of 175.20 g/mol and a density of 1.26 g/cm³, Indole-3-acetamide is comparable to common household items such as table salt in terms of molar mass and density.
The melting point of Indole-3-acetamide is approximately 147-148°C, while its boiling point is around 448.8°C. These values are higher than those of water, but lower than those of most metals commonly found in household items.
Indole-3-acetamide is sparingly soluble in water and has a low viscosity. Its solubility in water is comparable to that of sugar, while its viscosity is similar to that of vegetable oil.
🏭 Production & Procurement
Indole-3-acetamide, a key chemical compound used in various industries, is commonly produced through chemical synthesis in laboratory settings. This involves the reaction of indole with acetic anhydride to yield the desired product, Indole-3-acetamide. The purity and yield of the end product highly depend on the reaction conditions and the expertise of the chemists involved.
To procure Indole-3-acetamide, one can source it from chemical suppliers or manufacturers specializing in organic compounds. The compound is typically transported in sealed containers to prevent degradation and ensure its stability during transit. Due to its sensitive nature, proper handling and storage protocols must be adhered to in order to maintain the integrity of the product.
Upon arrival, Indole-3-acetamide must be stored in a cool, dry place away from direct sunlight and moisture to prevent any deterioration. It is important to carefully follow the recommended storage guidelines provided by the supplier to maintain the quality and stability of the compound. Additionally, proper labeling and documentation should be maintained to track the procurement, storage, and usage of Indole-3-acetamide in accordance with regulatory requirements.
⚠️ Safety Considerations
Safety considerations for Indole-3-acetamide should be taken into account due to its potential hazards. It is important to handle this compound with caution and to follow proper safety protocols when working with it. Protective measures such as wearing appropriate personal protective equipment, including gloves and goggles, are recommended to minimize the risk of exposure.
In terms of pharmacology, Indole-3-acetamide is a compound that has been studied for its potential medicinal properties. It has been shown to have anti-inflammatory and antioxidant effects, making it a promising candidate for the treatment of various diseases. Research is ongoing to further elucidate the mechanisms of action of Indole-3-acetamide and its potential therapeutic applications.
The hazard statements for Indole-3-acetamide include phrases such as “Causes skin irritation” and “May cause respiratory irritation.” These statements indicate the potential risks associated with exposure to this compound and the importance of taking appropriate precautions when handling it. It is crucial to follow safety guidelines and protocols to minimize the risk of harm.
Precautionary statements for Indole-3-acetamide include recommendations such as “Wear protective gloves/eye protection” and “Avoid breathing dust/fume/gas/mist/vapors/spray.” These statements highlight the importance of using proper protective equipment and ensuring proper ventilation when working with this compound. Following these precautionary measures can help to reduce the risk of adverse effects associated with Indole-3-acetamide exposure.
🔬 Potential Research Directions
Research on Indole-3-acetamide has shown its potential as a precursor for the biosynthesis of the important phytohormone indole-3-acetic acid (IAA), also known as auxin, which plays a key role in plant growth and development.
Further investigation into the enzymatic pathways involved in the conversion of Indole-3-acetamide to IAA could provide valuable insights into the regulation of auxin biosynthesis in plants, as well as potential targets for enhancing plant growth and productivity.
Studies focusing on the physiological effects of Indole-3-acetamide on plant growth, root development, and stress responses could elucidate its potential as a bioactive compound with applications in agriculture and horticulture.
🧪 Related Compounds
One similar compound to Indole-3-acetamide based upon molecular structure is Indole-3-acetic acid. This compound differs from Indole-3-acetamide by containing a carboxylic acid functional group instead of an amide group. Indole-3-acetic acid is a plant hormone involved in a variety of physiological processes, such as cell division, elongation, and differentiation.
Another compound with structural similarity to Indole-3-acetamide is Indole-3-acetonitrile. This compound differs in that it contains a nitrile functional group rather than an amide group. Indole-3-acetonitrile is a key intermediate in the biosynthesis of the plant hormone Indole-3-acetic acid. It is also used in the synthesis of various indole derivatives with potential biological activities.
A further compound structurally related to Indole-3-acetamide is Indole-3-acetaldehyde. This compound differs from Indole-3-acetamide by containing an aldehyde functional group instead of an amide group. Indole-3-acetaldehyde is involved in plant growth and development, with roles in stress responses, defense mechanisms, and signaling pathways. It is also a precursor to the biosynthesis of various biologically active compounds in plants.
