Hydroxyacetylaminofluorene is a chemical compound that has been studied for its potential impact on human health, specifically in relation to carcinogenesis and mutagenesis. While this compound may not directly impact individuals in their daily lives, research into its effects can contribute valuable insights into the development of strategies for cancer prevention and treatment. Therefore, understanding the properties and behavior of Hydroxyacetylaminofluorene is of significance to the scientific community and public health efforts more broadly.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Hydroxyacetylaminofluorene, a chemical compound primarily used in research and laboratory settings, has limited commercial and industrial applications. It is occasionally employed as an intermediate in the production of certain dyes and pharmaceuticals due to its structural properties and reactive nature.
In drug and medication applications, Hydroxyacetylaminofluorene has been studied for its potential carcinogenic and mutagenic effects. Its ability to interact with enzymes and DNA has led to research on its role in understanding the mechanisms of chemical-induced carcinogenesis, contributing to advancements in cancer treatment and prevention strategies. The compound’s pharmacological properties also make it a valuable tool in drug metabolism studies and toxicology research.
⚗️ Chemical & Physical Properties
Hydroxyacetylaminofluorene is a white crystalline solid with no distinctive odor at room temperature. Its crystalline structure gives it a sharp appearance under normal lighting conditions.
Hydroxyacetylaminofluorene has a molar mass of approximately 259.26 g/mol and a density of 1.36 g/cm³. These properties make it heavier and denser than commonly found household items such as sugar (180.16 g/mol, 1.59 g/cm³) and table salt (58.44 g/mol, 2.17 g/cm³).
The compound has a melting point of around 120-122°C and a boiling point of approximately 410-411°C. These values place Hydroxyacetylaminofluorene in the range of higher melting and boiling points compared to substances like butter (melting point of 32-35°C) and water (boiling point of 100°C).
Hydroxyacetylaminofluorene is slightly soluble in water and has a low viscosity. These properties differentiate it from common household items like sugar (highly soluble in water) and honey (high viscosity).
🏭 Production & Procurement
Hydroxyacetylaminofluorene is typically produced through a series of chemical reactions involving the acetylation of aminofluorene followed by hydroxylation. This process results in the formation of Hydroxyacetylaminofluorene, a compound commonly used in research laboratories and industrial settings for various purposes.
Procuring Hydroxyacetylaminofluorene can be done through specialized chemical suppliers who produce and distribute the compound in various quantities. Once procured, the compound is typically transported in sealed containers to prevent contamination or degradation during transit. It is important to follow proper handling and storage procedures to ensure the quality and integrity of Hydroxyacetylaminofluorene upon arrival at its destination.
Transporting Hydroxyacetylaminofluorene may require adherence to regulations governing the shipment of hazardous chemicals, depending on the quantity being transported. Proper labeling and documentation may be necessary to comply with safety standards and facilitate customs clearance if the compound is being transported internationally. It is essential to work with reputable suppliers and carriers to ensure the safe and efficient transport of Hydroxyacetylaminofluorene to its intended destination.
⚠️ Safety Considerations
Safety considerations for Hydroxyacetylaminofluorene include its potential to cause irritation to the skin, eyes, and respiratory tract. It is important to handle this compound with care, using appropriate personal protective equipment such as gloves, goggles, and a lab coat. Hydroxyacetylaminofluorene should be stored in a secure location away from incompatible materials to prevent hazardous reactions.
The pharmacology of Hydroxyacetylaminofluorene involves its ability to interact with DNA, leading to the formation of adducts. These adducts can result in mutations and potentially carcinogenic effects. Studies have shown that Hydroxyacetylaminofluorene can induce tumors in experimental animals, highlighting its genotoxic properties.
Hazard statements for Hydroxyacetylaminofluorene include “May cause cancer” and “Causes skin irritation.” It is important to be aware of these potential hazards when working with this compound and take necessary precautions to minimize risks. Proper ventilation and containment measures should be implemented to reduce exposure to Hydroxyacetylaminofluorene.
Precautionary statements for Hydroxyacetylaminofluorene recommend wearing protective clothing, gloves, and eye protection when handling this compound. In case of skin contact, it is advised to wash the affected area thoroughly with soap and water. If swallowed, medical attention should be sought immediately, and the individual should not induce vomiting unless instructed to do so by a healthcare professional.
🔬 Potential Research Directions
Research on Hydroxyacetylaminofluorene has the potential to investigate its chemical properties and structure through spectroscopic analysis. Understanding the molecular characteristics of this compound can lead to insights into its reactivity and potential applications in various fields.
Another potential research direction could involve exploring the biological effects of Hydroxyacetylaminofluorene on living organisms. This could include studying its toxicity, metabolic pathways, and potential interactions with cellular components. Such research could provide valuable information for assessing the safety and potential risks associated with exposure to this compound.
Furthermore, research on Hydroxyacetylaminofluorene could focus on its environmental impact and fate. Understanding how this compound interacts with the environment, such as its behavior in soil or water systems, can help inform risk assessments and environmental management strategies. This could involve studying its degradation pathways, transport mechanisms, and potential accumulation in various ecosystems.
🧪 Related Compounds
One similar compound to Hydroxyacetylaminofluorene based on molecular structure is N-Hydroxy-2-acetylaminofluorene. This compound also contains a hydroxyl group attached to the amine substituent on the fluorene moiety, similar to Hydroxyacetylaminofluorene. The acetyl group in this compound is also attached to the amine group, providing structural similarity to Hydroxyacetylaminofluorene.
Another compound similar to Hydroxyacetylaminofluorene is N-Hydroxy-2-acetylaminobiphenyl. This compound shares a common structural motif with Hydroxyacetylaminofluorene in that it contains an N-hydroxy group attached to an acetylaminobiphenyl moiety. The presence of both the acetyl group and the hydroxyl group in close proximity to the amine group contributes to the similarity between these two compounds.
Furthermore, N-Hydroxy-2-acetylaminobenzene is a compound that bears resemblance to Hydroxyacetylaminofluorene in terms of molecular structure. This compound features an acetylaminobenzene moiety with a hydroxyl group attached to the amine substituent, similar to the structure of Hydroxyacetylaminofluorene. The presence of both the acetyl and hydroxyl groups in this compound provides a molecular similarity to Hydroxyacetylaminofluorene.
