Furfurylamine, a chemical compound derived from furfural, holds significance in everyday life due to its use in various industries. It serves as a key building block in the production of agricultural chemicals, pharmaceuticals, and resins. In addition, furfurylamine plays a crucial role in the creation of polymers and coatings, contributing to the development of numerous consumer products such as adhesives, sealants, and coatings for paper and textiles. Its versatile applications underscore its importance in driving innovation and efficiency across multiple sectors, ultimately impacting the products and materials that individuals encounter in their daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Furfurylamine, also known as 2-furfurylamine, is a compound with various commercial and industrial applications. In the commercial sector, it is commonly used as a raw material in the production of resins, specifically furan resins. These resins are valued for their high heat resistance and are used in the manufacturing of foundry sand binders, composite materials, and coatings.
In the industrial realm, furfurylamine finds use as a building block in the production of pharmaceuticals, agrochemicals, and flavors. It is also utilized in the synthesis of heterocyclic compounds, polymers, and corrosion inhibitors. Additionally, furfurylamine serves as a precursor in the manufacture of various specialty chemicals, including furfuryl alcohol and tetrahydrofurfuryl alcohol, which have wide-ranging applications in industry.
Apart from its role in commercial and industrial settings, furfurylamine has potential drug and medication applications. Studies have shown that this compound exhibits antifungal and antibacterial properties, making it a promising candidate for development as a pharmaceutical agent. Furthermore, research suggests that furfurylamine may have neuroprotective effects and could be investigated for its potential therapeutic benefits in treating certain neurological disorders.
⚗️ Chemical & Physical Properties
Furfurylamine is a colorless to pale yellow liquid with a strong, unpleasant odor similar to that of ammonia or fish.
With a molar mass of 97.12 g/mol and a density of 1.051 g/cm³, furfurylamine is lighter than common food items like sugar (molar mass 342.3 g/mol, density 1.59 g/cm³) and salt (molar mass 58.44 g/mol, density 2.17 g/cm³).
Furfurylamine has a melting point of -51°C and a boiling point of 159°C, which is considerably lower than that of common food items like butter (melting point 32-35°C, boiling point 100°C) and chocolate (melting point 34-38°C, boiling point 160-170°C).
Furfurylamine is soluble in water and has a low viscosity, making it easily mixable in aqueous solutions. This contrasts with common food items like oil (insoluble in water) and honey (high viscosity), which have different solubility and viscosity characteristics.
🏭 Production & Procurement
Furfurylamine, also known as 2-furanamine, is commonly produced by the reaction of furfuryl alcohol with ammonia. This process typically involves the distillation of the resulting mixture to purify the desired product.
Furfurylamine can be procured from chemical suppliers that specialize in fine chemicals and intermediates. It is typically available in various purity grades, and can be purchased in bulk quantities for industrial applications. Transportation of Furfurylamine is typically done in sealed containers to prevent decomposition or contamination during transit.
When procuring Furfurylamine, it is important to ensure the proper handling and storage of the substance to prevent any degradation or safety hazards. Suppliers often provide guidelines for the safe handling and storage of Furfurylamine to maintain its integrity and ensure workplace safety. It is recommended to follow these guidelines to minimize risks associated with the handling of this chemical compound.
⚠️ Safety Considerations
Safety considerations for Furfurylamine include its potential to cause irritation to the skin, eyes, and respiratory tract. It is also flammable and may release toxic fumes when heated or exposed to fire. Proper personal protective equipment, such as gloves, goggles, and a respirator, should be used when handling this chemical. Additionally, Furfurylamine should be stored in a cool, dry, well-ventilated area away from sources of ignition.
Hazard statements for Furfurylamine include “Causes skin irritation”, “Causes serious eye irritation”, and “May cause respiratory irritation”. It is also classified as a flammable liquid and may release harmful fumes when exposed to heat or flame. Users should take precautions to minimize exposure and use appropriate safety equipment when handling this chemical.
Precautionary statements for Furfurylamine include “Wear protective gloves/eye protection/face protection”, “Use only outdoors or in a well-ventilated area”, and “Keep away from heat/sparks/open flames/hot surfaces”. It is important to handle this chemical with care and to follow all safety guidelines provided by the manufacturer. In the event of a spill, proper cleanup procedures should be followed to minimize potential risks.
🔬 Potential Research Directions
Research on furfurylamine has shown promising potential in several areas. One direction worth exploring is its use as a building block for the synthesis of various bioactive compounds. Additionally, investigating its role in organic reactions, such as its reactivity towards different functional groups, could provide valuable insights.
Furthermore, the study of furfurylamine’s pharmacological properties holds great promise. Research could be focused on its potential as a drug candidate for various medical conditions, as well as its interactions with receptors in the human body. Understanding its mechanism of action and potential side effects is crucial for further development.
Exploring the environmental impact of furfurylamine is another important research direction. Investigations could be conducted on its bioaccumulation in organisms, its degradation in the environment, and its potential toxicity to different ecosystems. This knowledge could guide policies and regulations regarding its use in various industries.
🧪 Related Compounds
One similar compound to Furfurylamine based upon molecular structure is 2-Furfurylamine. This compound is a derivative of furfurylamine, with a similar molecular structure and chemical properties. The only difference between the two compounds is the position of the amino group on the furan ring. 2-Furfurylamine is commonly used in organic synthesis and as a building block for various pharmaceuticals and agrochemicals.
Another similar compound to Furfurylamine is 3-Furfurylamine. Like 2-Furfurylamine, this compound is a derivative of furfurylamine with a slight variation in molecular structure. The amino group in 3-Furfurylamine is located at a different position on the furan ring compared to Furfurylamine. 3-Furfurylamine also finds applications in organic synthesis and as a precursor for the synthesis of various bioactive compounds.
4-Furfurylamine is yet another compound that bears similarity to Furfurylamine based on molecular structure. This compound differs from Furfurylamine in the position of the amino group on the furan ring. 4-Furfurylamine is utilized in diverse areas such as pharmaceuticals, agrochemicals, and material science for its versatile chemical properties. Like Furfurylamine, 4-Furfurylamine serves as a valuable building block in the synthesis of complex organic molecules.