Ethyl benzoylacetate is a chemical compound that is used in a variety of everyday products. It is commonly found in perfumes, cosmetics, and food flavorings. Its pleasant fruity odor makes it a popular choice for adding fragrance to these items. Additionally, ethyl benzoylacetate is used in the pharmaceutical industry as a flavoring agent in medications. Overall, the compound plays a significant role in enhancing the sensory experience of numerous consumer products that people encounter daily.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Ethyl benzoylacetate, also known as ethyl 2-oxo-2-phenylethanoate, finds multiple commercial and industrial applications. Its fruity and sweet scent makes it a popular ingredient in perfumes and fragrances. Additionally, it is used in the synthesis of pharmaceuticals and as a flavoring agent in the food industry.
In the field of drug and medication applications, ethyl benzoylacetate is utilized as an intermediate in the production of various pharmaceutical compounds. It is involved in the synthesis of drugs with sedative and anticonvulsant properties. Furthermore, this compound is used in the preparation of medications for treating conditions such as epilepsy and anxiety disorders.
⚗️ Chemical & Physical Properties
Ethyl benzoylacetate is a colorless liquid with a fruity odor, commonly described as sweet and floral. This compound is often used in the production of perfumes and flavorings due to its pleasant scent.
With a molar mass of around 194.21 g/mol and a density of approximately 1.09 g/cm³, Ethyl benzoylacetate is comparable to common food items such as sucrose in terms of molar mass, but slightly denser than substances like olive oil.
The melting point of Ethyl benzoylacetate is around -20°C, while its boiling point is approximately 174-175°C. These values are comparable to common food items like butter in terms of melting point, but higher than the boiling point of water.
Ethyl benzoylacetate is sparingly soluble in water, but readily dissolves in organic solvents. It has a relatively low viscosity compared to common food items like honey, making it easier to handle and mix in various applications.
🏭 Production & Procurement
Ethyl benzoylacetate is commonly produced through the Claisen condensation reaction. This involves the reaction of ethyl acetoacetate with benzoyl chloride in the presence of a base catalyst, typically sodium hydroxide. The resulting product is then purified through techniques such as distillation or recrystallization.
Ethyl benzoylacetate can be procured from chemical suppliers or manufacturers who specialize in the production of fine chemicals. It is often available in varying purities and quantities, depending on the specific requirements of the purchaser. Transportation of Ethyl benzoylacetate typically involves shipping in sealed containers or drums to prevent contamination or degradation during transit.
In order to ensure the safe handling and transportation of Ethyl benzoylacetate, proper labeling and packaging must be adhered to according to regulations set forth by governing bodies such as the Occupational Safety and Health Administration (OSHA) and the Department of Transportation (DOT). It is important for individuals involved in the procurement and transportation of Ethyl benzoylacetate to be aware of its potential hazards and to take necessary precautions to prevent accidents or exposure.
⚠️ Safety Considerations
Safety considerations for Ethyl benzoylacetate include its flammable nature, which requires proper storage away from any sources of ignition. The chemical should be handled in a well-ventilated area to prevent exposure to potentially harmful vapors. Personal protective equipment such as gloves and safety goggles should be worn when working with Ethyl benzoylacetate to prevent skin contact and eye irritation.
Hazard statements for Ethyl benzoylacetate include “May be harmful if swallowed, inhaled, or absorbed through the skin” and “Causes skin and eye irritation.” These statements highlight the potential risks associated with exposure to the chemical and emphasize the importance of following proper safety precautions when handling Ethyl benzoylacetate.
Precautionary statements for Ethyl benzoylacetate include “Keep away from heat, sparks, open flames, and hot surfaces” to prevent combustion risks. It is also advised to “Avoid breathing vapor or dust” and “Wear protective gloves/eye protection/clothing” when working with the chemical to minimize the risk of exposure. Proper disposal methods should be followed to prevent environmental contamination and ensure the safe handling of Ethyl benzoylacetate.
🔬 Potential Research Directions
Potential research directions for Ethyl benzoylacetate could encompass exploring its applications in organic synthesis, such as its use as a precursor in the synthesis of various pharmaceutical compounds.
Additionally, further investigation into the reactivity and functionalization of Ethyl benzoylacetate could shed light on possible modifications and derivatizations that could be employed for various chemical transformations.
Moreover, the study of the physical and chemical properties of Ethyl benzoylacetate may lead to the development of new chemical processes or reactions that could be utilized in the synthesis of valuable organic molecules.
🧪 Related Compounds
One similar compound to Ethyl benzoylacetate is Ethyl acetoacetate. This compound also contains an ethyl group attached to a carbonyl group, as well as a beta-ketoester moiety. Ethyl acetoacetate is commonly used as a building block in organic synthesis, particularly in the formation of beta-diketones through Claisen condensation reactions.
Another compound that shares structural similarities with Ethyl benzoylacetate is Ethyl acetylacetate. This compound contains an ethyl group attached to two carbonyl groups, giving it a beta-diketone structure. Ethyl acetylacetate is often used as a reagent in organic reactions, such as the formation of enolates for subsequent carbon-carbon bond formation.
A third compound akin to Ethyl benzoylacetate is Ethyl trifluoroacetoacetate. This compound contains an ethyl group attached to a trifluoroacetyl group and a beta-ketoester moiety. Ethyl trifluoroacetoacetate is known for its use as a reagent in fluorine chemistry, as well as in the synthesis of fluorinated organic compounds for pharmaceutical and agrochemical applications.
