Dl-Desthiobiotin is a compound that has significant relevance in everyday life due to its role in various biochemical studies, particularly in the field of biotin assays. This molecule is used as a competitive inhibitor in these assays, allowing for the accurate measurement of biotin levels in biological samples. As biotin is an essential vitamin for various physiological processes, including energy metabolism and cell growth, the precise quantification of its levels is crucial for understanding its impact on human health. By aiding in the accurate detection and measurement of biotin, dl-Desthiobiotin plays a key role in advancing our understanding of biotin’s role in human biology and its potential implications for disease prevention and treatment.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
dl-Desthiobiotin, a synthetic biotin analog, has various commercial and industrial applications. It is commonly used as a blocker for biotin-binding proteins in research and diagnostic assays. Additionally, dl-Desthiobiotin is utilized in the purification and immobilization of biotinylated molecules in biotechnology processes.
In terms of drug and medication applications, dl-Desthiobiotin has shown potential as a targeted therapy for certain diseases. It can act as a competitive inhibitor of biotin-dependent enzymes, making it a promising candidate for the treatment of disorders related to biotin metabolism. Research is ongoing to explore the therapeutic benefits of dl-Desthiobiotin in various clinical settings.
Overall, dl-Desthiobiotin’s versatility in both commercial and industrial settings, as well as its potential pharmaceutical applications, make it a valuable compound with a range of practical uses. Further studies and developments in the field may uncover new opportunities for the utilization of dl-Desthiobiotin in diverse industries and medical treatments.
⚗️ Chemical & Physical Properties
Dl-Desthiobiotin is a white crystalline solid that is odorless. It has a characteristic appearance of fine powder particles and does not exhibit any distinct smell.
The molar mass of dl-Desthiobiotin is approximately 254 g/mol, and its density is around 1.2 g/cm3. Compared to common household items, dl-Desthiobiotin has a higher molar mass and slightly higher density than water, which has a molar mass of 18 g/mol and a density of 1 g/cm3, respectively.
The melting point of dl-Desthiobiotin is typically around 202-207 degrees Celsius, while the boiling point is around 591 degrees Celsius. In comparison, common household items such as sugar have a melting point of around 186 degrees Celsius, and water boils at 100 degrees Celsius.
Dl-Desthiobiotin is sparingly soluble in water, forming a clear solution. It has a low viscosity, which means it flows easily. In contrast, common household items like salt are highly soluble in water, forming a cloudy solution, and have a higher viscosity.
🏭 Production & Procurement
dl-Desthiobiotin, a biotin analog, is typically produced through chemical synthesis in a laboratory setting. This process involves several steps, including the modification of natural biotin to remove the sulfur atom and create the desthiobiotin molecule. The final product, dl-Desthiobiotin, is then purified and formulated for use in research and medical applications.
Procurement of dl-Desthiobiotin can occur through various sources, such as chemical suppliers and research laboratories. The compound is often packaged in a solid form, such as powder or crystalline form, for ease of storage and transportation. When procuring dl-Desthiobiotin, it is essential to ensure proper handling and storage conditions to maintain its stability and integrity.
During transportation, dl-Desthiobiotin should be stored in a cool, dry environment to prevent degradation or contamination. It is crucial to follow proper labeling and packaging protocols to ensure the compound’s safety and integrity during transit. Additionally, proper documentation and regulations must be adhered to when transporting dl-Desthiobiotin across borders or internationally.
⚠️ Safety Considerations
Safety considerations for dl-Desthiobiotin are essential to prevent any potential risks associated with its use. When handling dl-Desthiobiotin, it is important to wear appropriate personal protective equipment, such as gloves and goggles, to minimize skin and eye contact. Additionally, proper ventilation should be ensured to prevent inhalation of the substance. It is crucial to store dl-Desthiobiotin in a cool, dry place away from direct sunlight and incompatible substances. Careful handling and adherence to safety protocols are paramount in preventing accidental exposure and ensuring the well-being of individuals working with dl-Desthiobiotin.
The pharmacology of dl-Desthiobiotin involves its role as a biotin analogue that competitively inhibits biotin-dependent enzymes, such as carboxylases. This inhibition can lead to disruptions in various metabolic pathways that rely on biotin-dependent enzymes, ultimately affecting processes like fatty acid synthesis and gluconeogenesis. dl-Desthiobiotin is commonly used in research settings to elucidate the roles of biotin-dependent enzymes and their impact on cellular metabolism. Understanding its pharmacological properties is crucial for designing experiments and interpreting results accurately.
Hazard statements for dl-Desthiobiotin include warnings of skin and eye irritation upon contact, as well as potential respiratory irritation if inhaled. It is also important to note that dl-Desthiobiotin may cause harm to aquatic organisms if released into the environment. Individuals handling dl-Desthiobiotin should be aware of these hazards and take appropriate precautions to prevent exposure. Proper disposal methods should be followed to minimize environmental impact.
Precautionary statements for dl-Desthiobiotin include recommendations to wash hands thoroughly after handling, avoid inhaling dust or fumes, and use protective clothing to prevent skin contact. In the event of accidental exposure or ingestion, medical attention should be sought immediately. Spills should be cleaned up promptly using appropriate methods and materials. Following these precautions will help to mitigate potential risks associated with dl-Desthiobiotin and ensure a safe working environment.
🔬 Potential Research Directions
One potential research direction for dl-Desthiobiotin is its use in studying cellular processes related to biotin metabolism. This can include investigating its role in biotin-dependent enzymes and pathways.
Furthermore, dl-Desthiobiotin can be explored for its potential therapeutic applications, particularly in diseases related to biotin deficiency or metabolic disorders. Research in this area can focus on developing novel drugs or treatments utilizing dl-Desthiobiotin.
Another possible avenue of research is studying the pharmacokinetics and bioavailability of dl-Desthiobiotin in different biological systems. This can help in understanding its potential efficacy and safety for various clinical applications.
🧪 Related Compounds
One similar compound to dl-Desthiobiotin based on its molecular structure is Desthiobiotin. This compound differs from dl-Desthiobiotin in that it lacks a chiral center, resulting in a racemic mixture. Desthiobiotin serves as a substrate for biotinyl enzymes and is commonly used in biochemical research and enzyme assays.
Another compound similar to dl-Desthiobiotin is d-Biotin. This compound is the D-enantiomer of biotin, a vitamin essential for various biochemical processes in organisms. d-Biotin plays a crucial role in carboxylation reactions and serves as a cofactor for biotin-dependent enzymes. Its structural similarity to dl-Desthiobiotin makes it a valuable tool in studies involving biotin metabolism and enzyme function.
dl-Desthiobiotin also bears resemblance to Biotin sulfoxide, a compound derived from the oxidation of biotin. Biotin sulfoxide retains the core structure of biotin but contains a sulfoxide group, which alters its chemical properties. This modification can impact the interactions of biotin sulfoxide with biotin-binding proteins and enzymes, offering insights into the role of specific functional groups in biotin-related processes.
