Dihydrolipoic Acid

Dihydrolipoic acid, a potent antioxidant, plays a crucial role in maintaining overall health by protecting cells from damage caused by free radicals. While its name may not be commonly recognized, its impact is significant in everyday life. By combating oxidative stress and promoting healthy cellular function, dihydrolipoic acid contributes to supporting the body’s natural defense mechanisms and potentially reducing the risk of chronic diseases. Incorporating sources of dihydrolipoic acid, such as certain foods or supplements, into one’s daily routine can contribute to overall well-being and longevity.

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💡 Commercial Applications

Dihydrolipoic Acid, also known as DHLA, has various commercial and industrial applications. One key use is as an antioxidant in skincare products and cosmetics due to its ability to protect against oxidative stress and free radical damage. Additionally, DHLA is employed in the food industry as a preservative to extend the shelf life of products.

In the realm of drug and medication applications, Dihydrolipoic Acid plays a vital role in mitigating oxidative stress and inflammation in various health conditions. It is utilized in dietary supplements to support overall health and well-being, particularly in individuals facing chronic diseases or conditions related to oxidative damage. Additionally, DHLA is being researched for its potential neuroprotective properties and its ability to improve age-related cognitive decline.

⚗️ Chemical & Physical Properties

Dihydrolipoic Acid is a colorless, crystalline solid with a characteristic sulfur-like odor. It is known for its ability to easily dissolve in common organic solvents, making it a versatile compound in various chemical reactions and processes.

With a molar mass of approximately 206.33 g/mol and a density of around 1.044 g/cm³, Dihydrolipoic Acid falls in line with common household items such as table salt (NaCl) in terms of molar mass, but is less dense than water (1 g/cm³). This compound is considered relatively lightweight and moderately dense when compared to other substances.

Dihydrolipoic Acid has a melting point of around 60-70°C and a boiling point of approximately 160-165°C. In comparison to common household items, its melting point is lower than that of sugar (sucrose) but higher than that of butter. Similarly, its boiling point is higher than that of alcohol but lower than that of water.

This compound exhibits high solubility in water, making it readily dispersible in aqueous solutions. Additionally, it possesses a relatively low viscosity, allowing for smooth mixing and reaction in liquid systems. Compared to common household items, Dihydrolipoic Acid shows similar solubility to sugar but lower viscosity than honey.

🏭 Production & Procurement

Dihydrolipoic Acid, also known as DHLA, is a compound that is primarily produced through chemical synthesis in a laboratory setting. The process of producing DHLA involves reducing Lipoic Acid, also known as LA, to its dihydro form to form DHLA.

Dihydrolipoic Acid can be procured from specialized chemical suppliers that offer high-purity forms of the compound for research and industrial purposes. The procurement of DHLA typically involves placing orders with these suppliers and arranging for the compound to be shipped to the desired location.

Once procured, Dihydrolipoic Acid can be transported in sealed and labeled containers to ensure its integrity during transit. Careful handling and storage of DHLA are essential to maintain its stability and prevent degradation before it is used for specific applications.

⚠️ Safety Considerations

Safety considerations for Dihydrolipoic Acid include the potential for skin and eye irritation. It is important to wear appropriate personal protective equipment when handling this substance, such as gloves and goggles. In case of contact with skin or eyes, rinse thoroughly with water and seek medical attention if irritation persists.

Dihydrolipoic Acid, also known as DHLA, is a natural antioxidant found in the body. It plays a key role in regulating the redox status of cells and protecting against oxidative stress. In addition, Dihydrolipoic Acid has been shown to have anti-inflammatory and neuroprotective properties. When used as a supplement, it is believed to support overall health and well-being.

Hazard statements for Dihydrolipoic Acid include being harmful if swallowed, causing skin irritation, and causing serious eye irritation. It is important to keep this substance out of reach of children and pets, and to store it in a cool, dry place away from direct sunlight. In case of ingestion, do not induce vomiting and seek medical attention immediately.

Precautionary statements for Dihydrolipoic Acid include wearing protective gloves and eye protection when handling, avoiding breathing in dust or fumes, and washing hands thoroughly after use. It is recommended to use this substance in a well-ventilated area to prevent inhalation of vapors. Additionally, it is important to dispose of Dihydrolipoic Acid properly according to local regulations.

🔬 Potential Research Directions

One potential research direction for Dihydrolipoic Acid is its role in combating oxidative stress and inflammation in various disease conditions. Studies may investigate its mechanism of action, dosage optimization, and potential side effects in different patient populations.

Researchers may also explore the potential protective effects of Dihydrolipoic Acid on the cardiovascular system, including its ability to improve endothelial function, lower blood pressure, and reduce the risk of cardiovascular events. Clinical trials could aim to elucidate the optimal supplementation strategy for cardiovascular health outcomes.

Furthermore, investigations into the neuroprotective properties of Dihydrolipoic Acid may prove fruitful, particularly in the context of neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Studies may focus on its ability to improve cognitive function, reduce neuroinflammation, and protect against neuronal damage in preclinical and clinical settings.

One compound similar to Dihydrolipoic Acid based upon molecular structure is Alpha Lipoic Acid. This compound shares a similar chemical structure with Dihydrolipoic Acid, containing two sulfhydryl groups. Alpha Lipoic Acid is also a powerful antioxidant and plays a key role in energy production within cells.

Another compound with a similar structure to Dihydrolipoic Acid is Glutathione. Glutathione is a tripeptide composed of cysteine, glycine, and glutamic acid, and contains a sulfhydryl group. Like Dihydrolipoic Acid, Glutathione is involved in cellular defense against oxidative stress and plays a vital role in detoxification processes in the body.

Coenzyme Q10 is yet another compound closely related to Dihydrolipoic Acid in terms of molecular structure. Also known as Ubiquinone, Coenzyme Q10 contains a benzoquinone ring and a long isoprenoid side chain. Like Dihydrolipoic Acid, Coenzyme Q10 functions as an antioxidant and is involved in energy production within mitochondria.

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