Diethyl ethylmalonate is a chemical compound commonly utilized in the manufacturing of pharmaceuticals, fragrances, and pesticides. Its relevance to everyday life lies in its role as a key ingredient in the production of these essential products. Pharmaceuticals containing Diethyl ethylmalonate help to treat various medical conditions, while fragrances incorporating this compound enhance the olfactory experience of personal care products. Likewise, pesticides formulated with Diethyl ethylmalonate contribute to crop protection and pest control efforts, ensuring the availability of safe and abundant food supplies. Thus, Diethyl ethylmalonate plays a significant role in enhancing and safeguarding the quality of everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Diethyl ethylmalonate, a compound with the chemical formula C11H18O4, has various commercial and industrial applications. It is widely used as a building block in the synthesis of various compounds such as pharmaceuticals, agrochemicals, and perfumes. The compound’s reactivity makes it a valuable intermediate in organic synthesis processes, particularly in the production of esters and other complex organic molecules.
In terms of drug and medication applications, Diethyl ethylmalonate is known for its role as a key precursor in the synthesis of vitamin B1 (thiamine). Vitamin B1 is essential for maintaining healthy nerve cells and supporting various bodily functions. Diethyl ethylmalonate’s use in the production of thiamine highlights its significance in the pharmaceutical industry and its contribution to improving human health. Furthermore, the compound’s versatility in organic chemistry makes it a valuable tool for developing new drugs and medications with enhanced therapeutic properties.
⚗️ Chemical & Physical Properties
Diethyl ethylmalonate is a colorless liquid with a fruity odor. Its appearance is similar to that of clear cooking oils commonly found in kitchens.
With a molar mass of 190.22 g/mol and a density of 1.03 g/cm^3, Diethyl ethylmalonate falls within the range of molar masses and densities of common food items such as vegetable oil and vinegar.
Diethyl ethylmalonate has a melting point of -50°C and a boiling point of 212°C. These properties are higher compared to most common food items, which typically have lower melting and boiling points.
Diethyl ethylmalonate is sparingly soluble in water and has a low viscosity. This contrasts with common food items like sugar and salt, which are highly soluble in water and have higher viscosities.
🏭 Production & Procurement
Diethyl ethylmalonate is typically produced through the esterification reaction of ethylmalonic acid with ethanol in the presence of a catalyst such as sulfuric acid. This reaction results in the formation of Diethyl ethylmalonate, which can then be extracted and purified through distillation or recrystallization.
Once produced, Diethyl ethylmalonate can be procured through commercial chemical suppliers or specialty chemical manufacturers. The compound is commonly available in various purities and quantities, making it accessible for research and industrial applications. Transportation of Diethyl ethylmalonate can be done using standard chemical transport methods, such as sealed containers or drums, to ensure safe and secure delivery to the desired location.
Alternatively, Diethyl ethylmalonate can also be synthesized in-house by skilled chemists or researchers using appropriate laboratory equipment and techniques. This DIY approach allows for greater control over the purity and quality of the compound, but requires knowledge and expertise in organic synthesis. Overall, the production and procurement of Diethyl ethylmalonate involves a combination of chemical reactions, purification processes, and transportation methods to ensure its availability for various applications in the chemical industry.
⚠️ Safety Considerations
Safety considerations for Diethyl ethylmalonate must be taken into account due to its potential hazards. It is important to handle this chemical with care by following strict safety procedures, wearing appropriate personal protective equipment (PPE), and working in a well-ventilated area. In case of accidental exposure, it is crucial to seek medical attention immediately and provide first aid as necessary.
Hazard statements for Diethyl ethylmalonate include “Causes skin irritation,” “Causes serious eye irritation,” and “Harmful if swallowed.” These statements highlight the potential risks associated with this chemical and emphasize the importance of proper handling and storage to prevent any adverse effects on human health and the environment.
Precautionary statements for Diethyl ethylmalonate advise individuals to wear protective gloves/eyewear/clothing, avoid inhalation or ingestion, and wash hands thoroughly after handling. Additionally, it is recommended to store this chemical in a cool, dry place away from sources of ignition and incompatible materials to reduce the risk of accidents or chemical reactions. Following these precautionary measures will help ensure the safe use of Diethyl ethylmalonate in laboratory or industrial settings.
🔬 Potential Research Directions
One potential research direction for Diethyl ethylmalonate is its use as a building block in organic synthesis reactions. Researchers may explore the varied reactivity of this compound in different conditions to produce a range of valuable products.
Another avenue for study could be the investigation of the anticancer properties of Diethyl ethylmalonate. Studies have shown that certain derivatives of ethylmalonate exhibit promising cytotoxic effects on cancer cells, making it a potentially valuable compound in the development of new cancer therapeutics.
Furthermore, researchers may also focus on the green chemistry applications of Diethyl ethylmalonate. By exploring more sustainable and environmentally friendly methods for synthesizing this compound, scientists could contribute to the ongoing efforts to minimize the environmental impact of chemical reactions.
🧪 Related Compounds
One similar compound to Diethyl ethylmalonate is Dimethyl methylmalonate. This compound has the same molecular formula of C8H14O4 as Diethyl ethylmalonate. It also contains a malonate ester group, but with different alkyl substituents.
Another compound structurally similar to Diethyl ethylmalonate is Ethyl diethylmalonate. This compound has the molecular formula C10H18O4 and contains two ethyl groups attached to the malonate ester group. Despite the difference in alkyl substituents, Ethyl diethylmalonate shares similarities in structure with Diethyl ethylmalonate.
A final compound with a similar structure to Diethyl ethylmalonate is Dimethyl ethylmalonate. This compound, with the formula C7H12O4, has an ethyl group and a methyl group attached to the malonate ester group. While differing in alkyl substituents, Dimethyl ethylmalonate exhibits structural similarities to Diethyl ethylmalonate.
