Cloperastine, a non-narcotic antitussive agent, is relevant to everyday life as it is commonly used to suppress coughing. Whether due to a common cold, allergies, or other respiratory illnesses, coughing can disrupt daily activities and cause discomfort. By effectively suppressing cough symptoms, Cloperastine can contribute to improved quality of life and overall well-being for individuals experiencing these symptoms. Its ability to provide relief from coughing illustrates its relevance in helping individuals remain productive and comfortable in their daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Cloperastine, a drug primarily used as an antitussive agent, has limited commercial and industrial applications outside of the pharmaceutical industry. Its main purpose is to treat coughs caused by respiratory tract disorders such as bronchitis and asthma.
In the realm of drug and medication applications, Cloperastine is commonly utilized in various cough syrups and cough medications in both over-the-counter and prescription forms. It acts by suppressing the cough reflex in the brain, providing relief to individuals suffering from persistent coughing.
Moreover, Cloperastine has shown effectiveness in reducing cough frequency and intensity, making it a valuable component in treating coughs associated with conditions such as chronic obstructive pulmonary disease (COPD) and respiratory infections. Its ability to alleviate cough symptoms has made it a popular choice among healthcare professionals and patients alike.
⚗️ Chemical & Physical Properties
Cloperastine is a white crystalline powder with no distinct odor. It is commonly found in pharmaceutical preparations such as cough syrups due to its antitussive properties.
With a molar mass of approximately 332.4 g/mol and a density of 1.26 g/cm³, Cloperastine is fairly comparable to common food items like sugar (molar mass around 342.3 g/mol, density around 1.59 g/cm³).
Cloperastine has a melting point of around 217-219°C and a boiling point of approximately 452.4°C. When compared to common food items like salt and sugar, which have much lower melting and boiling points, Cloperastine exhibits higher thermal stability.
Cloperastine is sparingly soluble in water and exhibits a medium viscosity. This places it in between common food items like salt (high solubility, low viscosity) and sugar (high solubility, medium viscosity).
🏭 Production & Procurement
Cloperastine, a drug with antitussive properties, is produced through a complex chemical synthesis process involving multiple steps. Starting materials such as 3-(2-methoxyphenoxy)propane-1,2-diol are utilized to generate the desired compound Cloperastine.
Once the synthesis of Cloperastine is completed, the drug can be procured from pharmaceutical companies that specialize in its production. Cloperastine is commonly available in the form of tablets, syrups, or liquid formulations, which can be transported via standard shipping methods to distribution centers and pharmacies.
Pharmacists and healthcare professionals are responsible for prescribing and dispensing Cloperastine to patients in need of its antitussive effects. Patients can consult their healthcare provider to obtain a prescription for Cloperastine, which can then be filled at a local pharmacy for use in managing cough symptoms.
⚠️ Safety Considerations
Safety considerations for Cloperastine should be carefully observed due to its potential for adverse effects. The drug may cause drowsiness and impair the ability to operate machinery or drive a vehicle, which can pose a significant safety risk. It is important for individuals taking Cloperastine to exercise caution when engaging in activities that require alertness. Additionally, there may be an increased risk of side effects when combining Cloperastine with alcohol or other central nervous system depressants. It is crucial for healthcare providers to educate patients on these safety considerations to prevent any potential harm.
Hazard statements for Cloperastine include the risk of drowsiness and impairment of motor skills. Individuals taking Cloperastine should be aware of these potential hazards and avoid activities that require alertness, such as driving or operating heavy machinery. The drug may also interact with other medications, leading to an increased risk of side effects. It is essential for patients to discuss any other medications they are taking with their healthcare provider to prevent any adverse reactions.
Precautionary statements for Cloperastine involve advising individuals to avoid consuming alcohol while taking the medication to reduce the risk of drowsiness and impaired motor function. Patients should also be cautioned about the potential for interactions with other central nervous system depressants, which can increase the likelihood of adverse effects. It is recommended for healthcare providers to closely monitor patients for any signs of complications or side effects while taking Cloperastine to ensure their safety and well-being.
🔬 Potential Research Directions
Cloperastine, a centrally acting antitussive agent, has been the subject of interest in various pharmacological studies due to its potential therapeutic effects on respiratory disorders. Research on cloperastine has mainly revolved around its mechanisms of action in suppressing cough reflexes and its efficacy in treating acute and chronic cough.
Further investigations on cloperastine could focus on exploring its potential as a treatment option for different types of cough, including those associated with upper respiratory tract infections, asthma, and chronic obstructive pulmonary disease. Studies may also delve into the comparative efficacy of cloperastine versus other antitussive agents to determine its place in clinical management protocols.
Additionally, research on the safety profile and potential drug interactions of cloperastine may provide valuable insights for healthcare providers when prescribing this medication. Pharmacokinetic studies could offer crucial information on the drug’s absorption, distribution, metabolism, and excretion, aiding in optimizing dosage regimens and minimizing adverse effects in patients.
🧪 Related Compounds
One compound similar to Cloperastine based on its molecular structure is Dextromethorphan. Dextromethorphan is a cough suppressant that functions by decreasing the urge to cough. Like Cloperastine, Dextromethorphan is a derivative of morphinan.
Another compound with a molecular structure similar to Cloperastine is Levocloperastine. Levocloperastine is an antitussive agent used to treat dry, unproductive cough. Like Cloperastine, Levocloperastine acts on the central nervous system to suppress the cough reflex.
Additionally, Noscapine is a compound structurally related to Cloperastine. Noscapine is a non-opioid antitussive that suppresses cough by acting on the brainstem. Both Noscapine and Cloperastine are benzylisoquinoline alkaloids with cough-suppressant properties.
