Beta-picoline is a chemical compound that plays a crucial role in various industries such as pharmaceuticals, agrochemicals, and materials science. It is commonly used as a building block in the synthesis of numerous products, including drugs, pesticides, and specialty chemicals. Beta-picoline’s versatile applications contribute to advancements in healthcare, agriculture, and materials development, making it an essential component in our everyday lives. Its significance lies in its ability to serve as a fundamental ingredient in the production of a wide range of essential goods that ultimately impact individuals and industries worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Beta-PICOLINE, a derivative of pyridine, finds various commercial and industrial applications due to its properties. It is commonly used as a building block in the production of agrochemicals, pharmaceuticals, and specialty chemicals. The compound’s ability to form complexes with transition metals makes it valuable in catalysts for organic reactions.
In the pharmaceutical industry, beta-PICOLINE plays a crucial role in the synthesis of drugs and medications. It is used as a starting material for the production of Nicotinamide, a form of Vitamin B3 commonly found in supplements and medications. Additionally, beta-PICOLINE is used in the manufacturing of some antimalarial drugs due to its chemical properties.
Due to its versatile nature and compatibility with various chemical processes, beta-PICOLINE has become a staple in the production of a wide range of products. From pesticides to pharmaceuticals, this compound has proven to be an essential ingredient in many industrial applications. Its ability to contribute to the synthesis of complex molecules makes it a valuable tool in modern chemistry.
⚗️ Chemical & Physical Properties
Beta-Picoline, also known as 3-methylpyridine, appears as a colorless liquid with a pungent odor reminiscent of ammonia. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its chemical properties.
With a molar mass of 93.13 g/mol and a density of 0.978 g/cm^3 at room temperature, beta-Picoline is lighter than common household items such as water (18.02 g/mol, 1.00 g/cm^3) and ethanol (46.07 g/mol, 0.789 g/cm^3). This makes it less dense compared to these everyday substances.
Beta-Picoline has a melting point of -24.7°C and a boiling point of 144.1°C. In comparison, water freezes at 0°C and boils at 100°C, while ethanol freezes at -114.1°C and boils at 78.37°C. This indicates that beta-Picoline’s melting and boiling points are higher than those of water and lower than those of ethanol.
Beta-Picoline is soluble in water to a limited extent and has a relatively low viscosity. This differs from common household items such as sugar, which is highly soluble in water, and honey, which has a high viscosity. Beta-Picoline’s solubility in water and viscosity fall between these two substances.
🏭 Production & Procurement
In the chemical industry, beta-PICOLINE is primarily produced through the reaction of acetaldehyde with ammonia and acetaldehyde cyanohydrin. This synthesis process yields beta-PICOLINE as a key intermediate in the production of various chemicals and pharmaceuticals.
Beta-PICOLINE can be procured from chemical manufacturers or suppliers specializing in fine chemicals and intermediates. The compound may be transported in liquid form within sealed containers, such as drums or tankers, to ensure its stability during transit. Specialized handling procedures may be required due to its potential reactivity with certain substances.
Due to its flammability and potential health hazards, beta-PICOLINE must be procured and handled with care in accordance with relevant safety regulations and guidelines. Customers seeking to procure this compound for industrial applications should ensure they are working with reliable suppliers who comply with industry standards for quality and safety. Proper labeling and documentation are essential for the safe transportation and handling of beta-PICOLINE.
⚠️ Safety Considerations
Safety considerations for beta-PICOLINE involve its potential for skin and eye irritation. It is recommended to handle beta-PICOLINE with appropriate personal protective equipment, such as gloves and safety glasses, to prevent contact with skin or eyes. In case of accidental exposure, the affected area should be immediately rinsed with water.
Beta-PICOLINE, a derivative of pyridine, is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It exhibits moderate toxicity, with a reported LD50 value in rats of approximately 1000 mg/kg. Beta-PICOLINE is metabolized in the liver and excreted primarily in the urine.
Hazard statements for beta-PICOLINE include “causes skin irritation” and “causes serious eye irritation.” Exposure to beta-PICOLINE may result in irritation, redness, and swelling of the skin, as well as irritation and redness of the eyes. It is important to avoid prolonged or repeated contact with beta-PICOLINE to prevent adverse effects.
Precautionary statements for beta-PICOLINE involve handling the compound with care to minimize the risk of exposure. It is recommended to work with beta-PICOLINE in a well-ventilated area to prevent inhalation of vapors. In case of accidental exposure, it is advised to seek medical attention and provide the SDS (Safety Data Sheet) for beta-PICOLINE to healthcare professionals.
🔬 Potential Research Directions
One potential research direction of beta-PICOLINE lies in its role as a building block in the synthesis of pharmaceutical compounds. Further investigation could explore its potential as a precursor in the development of new drugs and medicines.
Another potential avenue of research could focus on the use of beta-PICOLINE as a ligand in coordination chemistry. This area of study could shed light on the complexation behavior and reactivity of beta-PICOLINE with various metal ions, contributing to the understanding of coordination chemistry principles.
Additionally, research into the environmental impact of beta-PICOLINE and its derivatives could be of interest. Studies on the degradation pathways, toxicity, and bioaccumulation potential of beta-PICOLINE in various ecosystems could provide valuable insights into its environmental fate and potential risks.
🧪 Related Compounds
One similar compound to beta-PICOLINE is alpha-PICOLINE, which differs in the position of the methyl group on the pyridine ring. While beta-PICOLINE has the methyl group at the beta position, alpha-PICOLINE has it at the alpha position. This positional isomerism results in different chemical properties and reactivities between the two compounds.
Another related compound is gamma-PICOLINE, in which the methyl group is located at the gamma position on the pyridine ring. Like beta-PICOLINE, gamma-PICOLINE is an important building block in the synthesis of various compounds. The positioning of the methyl group in gamma-PICOLINE leads to distinct steric effects and electronic properties compared to beta-PICOLINE.
Delta-PICOLINE is yet another compound similar to beta-PICOLINE, with the methyl group situated at the delta position on the pyridine ring. This positional isomer exhibits unique reactivity and properties due to the specific arrangement of atoms in the molecule. Delta-PICOLINE, like other PICOLINE isomers, finds applications in various industries such as pharmaceuticals, agrochemicals, and organic synthesis.
