Benzoylformic acid, also known as phenylglyoxylic acid, holds significance in everyday life due to its diverse applications in various industries. This compound is commonly utilized in the field of pharmaceuticals for the synthesis of biologically active molecules. Additionally, it is a key ingredient in the production of fragrances, dyes, and pesticides. Furthermore, benzoylformic acid plays a vital role in organic chemistry research, serving as a starting material for the preparation of numerous compounds. Its versatility and utility make it an essential component in the manufacturing processes that contribute to the products we encounter in our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Benzoylformic acid, also known as benzoylacetic acid, is commonly utilized in several commercial and industrial applications. This chemical compound is often used as a precursor in the synthesis of various pharmaceuticals, fragrances, and agrochemicals. Additionally, benzoylformic acid is employed in the production of dyes, plastics, and specialty chemicals due to its versatile chemistry.
In the realm of drug and medication applications, benzoylformic acid plays a crucial role as a building block for the synthesis of certain drugs. It is frequently employed in the pharmaceutical industry to create antihistamines, anti-inflammatories, and anti-cancer agents. Moreover, benzoylformic acid is utilized in the synthesis of active pharmaceutical ingredients (APIs) for medications aimed at treating various diseases and ailments.
The unique properties of benzoylformic acid make it a valuable component in the development of novel drugs and medications. Its ability to undergo different chemical reactions enables researchers and pharmacologists to explore a wide range of therapeutic possibilities. Through strategic manipulation of its chemical structure, benzoylformic acid can be tailored to yield diverse pharmaceutical compounds with potential applications in medicine and healthcare.
⚗️ Chemical & Physical Properties
Benzoylformic acid is a white crystalline solid with a faint odor. It is sparingly soluble in water but dissolves in common organic solvents such as ethanol and acetone.
With a molar mass of 164.15 g/mol and a density of 1.257 g/cm³, Benzoylformic acid is heavier than common household items like sugar (molar mass of 342.30 g/mol, density of 1.59 g/cm³) but lighter than salt (molar mass of 58.44 g/mol, density of 2.16 g/cm³).
The melting point of Benzoylformic acid is around 162-164°C, while its boiling point is approximately 385-395°C. This makes it higher in melting point compared to sugar (melting point of 186°C) but lower than salt (melting point of 801°C), and lower in boiling point compared to both sugar (boiling point of 1,580°C) and salt (boiling point of 1,465°C).
Benzoylformic acid has low solubility in water and exhibits a relatively low viscosity. This differs from common household items like sugar and salt, which have high solubility in water and do not exhibit significant viscosity.
🏭 Production & Procurement
Benzoylformic acid, also known as alpha-oxo-alpha-phenylacetic acid, is a compound commonly used in organic synthesis and pharmaceutical research. The production of Benzoylformic acid typically involves the oxidation of benzaldehyde with potassium permanganate, followed by hydrolysis of the resulting benzoyl alcohol.
The procurement of Benzoylformic acid can be achieved through various chemical suppliers and manufacturers. It is commonly available in both solid and liquid forms, depending on its intended use. Transportation of Benzoylformic acid is typically done in sealed containers to prevent contamination and ensure its purity during transit.
Due to its potential hazards and reactivity, Benzoylformic acid should be handled with care and stored in a cool, dry place away from heat and direct sunlight. Proper labeling and documentation of Benzoylformic acid shipments are essential for regulatory compliance and safety considerations. It is important to follow established guidelines and protocols for the safe handling and disposal of Benzoylformic acid to prevent any accidents or environmental harm.
⚠️ Safety Considerations
Safety Considerations for Benzoylformic acid:
Benzoylformic acid should be handled with care and caution due to its potential health hazards. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with this compound. It is also essential to work in a well-ventilated area to prevent inhalation of toxic fumes. Proper storage of Benzoylformic acid is crucial to prevent accidental spills or leaks.
Pharmacology of Benzoylformic acid:
Benzoylformic acid is primarily used as a precursor in the synthesis of various pharmaceutical compounds. It acts as a building block in the production of certain drugs that have analgesic and anti-inflammatory properties. When administered in the appropriate dosage and form, these drugs can be effective in managing pain and inflammation in patients.
Hazard Statements for Benzoylformic acid:
Benzoylformic acid may cause skin irritation and serious eye damage upon contact. It is harmful if swallowed and may cause respiratory irritation if inhaled. This compound is also toxic to aquatic life with long-lasting effects. It is important to handle Benzoylformic acid with extreme caution to avoid any potential hazards to health or the environment.
Precautionary Statements for Benzoylformic acid:
When working with Benzoylformic acid, it is essential to wear protective gloves, clothing, and eye protection. Avoid breathing in the fumes or vapors of this compound, and ensure proper ventilation in the work area. In case of skin contact, immediately wash the affected area with soap and water. If Benzoylformic acid is ingested or inhaled, seek medical attention immediately and provide the relevant first aid measures. Properly dispose of any unused or contaminated Benzoylformic acid according to local regulations.
🔬 Potential Research Directions
One potential research direction for Benzoylformic acid could be investigating its potential biological activities and pharmacological properties. This could involve studying its effects on different biological systems and identifying any potential therapeutic applications.
Another research direction could focus on the synthesis and development of novel derivatives of Benzoylformic acid. Researchers could explore modifying its chemical structure to enhance its reactivity, stability, and potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science.
Additionally, there is potential for research on the environmental impact of Benzoylformic acid and its derivatives. Studies could investigate their degradation pathways, toxicity, and potential risks to ecosystems. This research could contribute to a better understanding of their environmental fate and inform regulations on their use.
🧪 Related Compounds
One similar compound to Benzoylformic acid based upon molecular structure is Benzoyl acetic acid. This compound differs from Benzoylformic acid in that it contains an additional methyl group attached to the carboxyl group. The presence of this methyl group alters the compound’s chemical and physical properties compared to Benzoylformic acid.
Another compound similar in structure to Benzoylformic acid is Benzoylacetic acid. This compound shares the benzoyl group attached to the carboxyl group with Benzoylformic acid but contains an additional methyl group on the alpha carbon. This structural difference affects the compound’s reactivity and biological activity compared to Benzoylformic acid.
An additional compound resembling Benzoylformic acid in structure is Benzoylpropionic acid. This compound contains a benzoyl group attached to the carboxyl group, similar to Benzoylformic acid, but has an additional methylene group between the benzoyl group and the carboxyl group. This structural variation can impact the compound’s solubility, stability, and biological activity relative to Benzoylformic acid.
