Benzoylacetone is a chemical compound that has various applications in everyday life. It is commonly utilized in the production of perfumes and flavorings due to its aromatic properties. Additionally, Benzoylacetone is used in the synthesis of pharmaceuticals and as a precursor for organic reactions in chemical synthesis. Overall, Benzoylacetone plays a significant role in the fragrance and pharmaceutical industries, contributing to the creation of everyday products found in households worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Benzoylacetone, also known as dibenzoylmethane, has several commercial and industrial applications. It is commonly used as a chemical intermediate in the production of various pharmaceuticals, perfumes, and flavors. Benzoylacetone is also utilized as a photoinitiator in the polymerization process of coatings and adhesives.
In addition to its commercial and industrial uses, Benzoylacetone has been found to have potential drug and medication applications. It has shown promising results as a potential anti-cancer agent due to its ability to inhibit cell growth and induce apoptosis in cancer cells. Furthermore, Benzoylacetone has been studied for its potential anti-inflammatory and antioxidant properties, making it a promising candidate for the development of new drug therapies.
Overall, Benzoylacetone’s diverse range of applications, from commercial and industrial uses to potential drug and medication applications, highlight its importance in various fields such as pharmaceuticals, cosmetics, and materials science. Its unique chemical structure and properties continue to make it a valuable compound for further research and development in various industries.
⚗️ Chemical & Physical Properties
Benzoylacetone is a pale yellow crystalline solid with a pleasant fruity odor. It is commonly used as a flavoring agent in food products due to its aromatic properties.
With a molar mass of approximately 164.20 g/mol and a density of around 1.17 g/cm³, benzoylacetone is heavier than common food items like sugar and salt. Its molar mass and density contribute to its stability and longevity in food products.
Benzoylacetone has a melting point of around 42°C and a boiling point of approximately 144°C. These values are higher compared to common food items, making benzoylacetone more stable at higher temperatures.
Benzoylacetone is sparingly soluble in water and has a low viscosity, contributing to its ease of use in food applications. These properties contrast with common food items which are typically more soluble in water and have varying viscosities depending on type.
🏭 Production & Procurement
Benzoylacetone is typically produced through a Friedel-Crafts acylation reaction between benzene and ethyl acetoacetate in the presence of a Lewis acid catalyst, such as aluminum chloride. This process results in the formation of benzoylacetone as a key intermediate compound.
Once Benzoylacetone is produced, it can be procured from chemical suppliers or manufacturers specializing in fine chemicals. The compound is typically available in the form of a colorless or pale yellow liquid with a characteristic odor. Benzoylacetone can be transported in sealed containers to prevent leakage or contamination during transit.
When Benzoylacetone is being transported, it is important to adhere to strict safety regulations and guidelines to prevent exposure to individuals handling the compound. Proper labeling, packaging, and handling procedures should be followed to ensure the safe transport of Benzoylacetone to its intended destination for further processing or use.
⚠️ Safety Considerations
Safety Considerations for Benzoylacetone:
Benzoylacetone is a chemical compound that poses certain safety considerations when handling. It is important to be cautious when working with this substance, as it may cause irritation to the skin, eyes, and respiratory system. It is essential to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat, when working with benzoylacetone to prevent contact and minimize exposure.
Additionally, benzoylacetone should be stored in a cool, dry place away from heat sources, open flames, and incompatible materials. Proper ventilation is crucial when handling this compound to prevent the buildup of vapors in the air. In case of accidental exposure, it is advised to rinse the affected area with plenty of water and seek medical attention if necessary.
Hazard Statements for Benzoylacetone:
The hazard statements for benzoylacetone include “Causes skin irritation,” “May cause respiratory irritation,” and “Causes serious eye irritation.” These statements indicate that exposure to benzoylacetone can result in harmful effects on the skin, respiratory system, and eyes. It is crucial to handle this compound with care and follow proper safety protocols to minimize the risks associated with its use.
Precautionary Statements for Benzoylacetone:
The precautionary statements for benzoylacetone include “Wear protective gloves/protective clothing/eye protection/face protection,” “Avoid breathing dust/fume/gas/mist/vapors/spray,” and “IF ON SKIN: Wash with plenty of soap and water.” These statements provide important guidelines for safe handling of benzoylacetone to reduce the risk of exposure and potential harm. It is essential to follow these precautionary measures to ensure the safety of individuals working with this compound.
🔬 Potential Research Directions
Potential research directions for benzoylacetone include investigating its potential applications in organic synthesis due to its ability to undergo various reactions such as Claisen–Schmidt condensation and the Knorr pyrazole synthesis. Additionally, studies could explore its role as a chelating ligand in coordination chemistry, as its carbonyl and α-methyl groups make it a versatile candidate for metal ion complexation. Furthermore, research could delve into the biological activities of benzoylacetone and its derivatives, aiming to uncover potential therapeutic properties or pharmacological applications in medicine.
🧪 Related Compounds
One similar compound to Benzoylacetone based upon molecular structure is Acetophenone. This compound consists of a phenyl group attached to a carbonyl group, similar to the structure of Benzoylacetone. Acetophenone is commonly used in the production of fragrances and flavors due to its aromatic properties.
Another compound with a similar molecular structure to Benzoylacetone is Methyl Benzoylformate. This compound contains a benzoyl group attached to a carbonyl group, similar to Benzoylacetone. Methyl Benzoylformate is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
Additionally, Chalcone shares a similar molecular structure to Benzoylacetone. This compound consists of two aromatic rings connected by a carbonyl group, similar to the structure of Benzoylacetone. Chalcone is known for its biological activities and is studied for its potential medicinal properties.
