Benzenesulfonyl chloride, 3,4-dichloro- may seem like a complex chemical compound with limited relevance to everyday life. However, it plays a significant role in various industries such as pharmaceuticals, agrochemicals, and materials science. This compound serves as a key building block in the synthesis of various drugs, pesticides, and advanced materials. Its versatility and reactivity make it an essential component in the production of a wide range of products that impact our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Benzenesulfonyl chloride, 3,4-dichloro- is commonly used in the commercial and industrial sectors as a key intermediate in the production of pharmaceuticals, dyes, and agrochemicals. It is a versatile compound that can undergo various chemical reactions to yield a wide range of products with diverse applications.
In the pharmaceutical industry, Benzenesulfonyl chloride, 3,4-dichloro- is utilized as a valuable building block for the synthesis of a variety of drugs and medications. It is commonly employed in the manufacture of pharmaceutical compounds due to its reactivity and ability to introduce specific functional groups into organic molecules.
Furthermore, Benzenesulfonyl chloride, 3,4-dichloro- is instrumental in the development of new therapeutic agents and medicinal products. Its chemical properties allow for the modification of drug molecules to enhance their efficacy, bioavailability, and pharmacological profile. As a result, this compound plays a critical role in the advancement of pharmaceutical research and development.
⚗️ Chemical & Physical Properties
Benzenesulfonyl chloride, 3,4-dichloro-, is a colorless liquid with a sharp, pungent odor. It is highly reactive and can cause irritation to the eyes, skin, and respiratory tract upon contact.
With a molar mass of approximately 221.00 g/mol and a density of about 1.63 g/cm³, Benzenesulfonyl chloride, 3,4-dichloro-, is heavier than common food items such as sugar and flour in terms of molar mass and density. This compound is denser and more concentrated compared to most food substances.
The melting point of Benzenesulfonyl chloride, 3,4-dichloro-, is around 71-73°C, while the boiling point is approximately 344-345°C. These values are significantly higher than those of common food items like butter and chocolate, making this chemical compound relatively more stable and resistant to changes in temperature.
Benzenesulfonyl chloride, 3,4-dichloro-, is sparingly soluble in water, with a low viscosity. Its solubility in water is much lower than that of typical food items like salt and sugar. Additionally, its viscosity is lower compared to honey or syrup, making it less sticky and easier to handle in a laboratory setting.
🏭 Production & Procurement
Benzenesulfonyl chloride, 3,4-dichloro- is produced through a multistep process starting with the chlorosulfonation of benzene to form benzenesulfonyl chloride. The 3,4-dichloro- derivative is then obtained by subsequent chlorination of the sulfonyl chloride intermediate.
Benzenesulfonyl chloride, 3,4-dichloro- can be procured from chemical suppliers specializing in fine chemicals. It is typically transported in sealed containers to prevent exposure to moisture and air, which can degrade the compound. Proper labeling and handling procedures should be followed to ensure safe transportation and storage.
Upon procurement, Benzenesulfonyl chloride, 3,4-dichloro- should be stored in a cool, dry place away from sources of heat and light. It is important to adhere to all safety guidelines when handling this compound, as it is corrosive and can cause severe skin and eye irritation. Proper ventilation should be maintained in areas where the compound is stored or used.
⚠️ Safety Considerations
Safety considerations for Benzenesulfonyl chloride, 3,4-dichloro- revolve around its potential health hazards and reactivity. This compound is a strong electrophile and can react violently with water, alcohols, and bases, leading to the release of toxic gases. It is also highly corrosive and can cause severe skin burns and eye damage upon contact. Therefore, proper personal protective equipment, such as gloves, goggles, and a lab coat, should be worn when handling this compound. Additionally, Benzenesulfonyl chloride, 3,4-dichloro- should be stored in a cool, dry place away from sources of ignition and incompatible materials.
Hazard statements for Benzenesulfonyl chloride, 3,4-dichloro- include “Causes severe skin burns and eye damage” and “May cause an allergic skin reaction.” These statements highlight the potential health hazards associated with exposure to this compound. It is important to handle Benzenesulfonyl chloride, 3,4-dichloro- with caution and to follow proper safety protocols to minimize the risk of harm.
Precautionary statements for Benzenesulfonyl chloride, 3,4-dichloro- include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.” These statements emphasize the importance of using appropriate personal protective equipment and taking quick action in case of exposure to Benzenesulfonyl chloride, 3,4-dichloro-. It is crucial to follow these precautions to ensure the safe handling of this compound and to minimize the risk of harm to oneself or others.
🔬 Potential Research Directions
One potential research direction for Benzenesulfonyl chloride, 3,4-dichloro- is its application in organic synthesis as a versatile building block for the synthesis of various biologically active compounds. Researchers could explore different reaction conditions and catalysts to optimize the synthesis of target molecules.
Another research direction could focus on the development of methods for the regioselective functionalization of the benzene ring in Benzenesulfonyl chloride, 3,4-dichloro-. By selectively modifying one of the chlorine atoms, researchers could potentially access a variety of new compounds with diverse chemical properties and applications.
Furthermore, investigation into the reactivity of Benzenesulfonyl chloride, 3,4-dichloro- towards different nucleophiles could lead to the discovery of novel reaction pathways and mechanisms. Understanding the reactivity of this compound could provide valuable insights into the design of more efficient and selective chemical reactions.
🧪 Related Compounds
One similar compound to Benzenesulfonyl chloride, 3,4-dichloro- is Benzenesulfonyl chloride, 2,4-dichloro-. This compound has a molecular structure similar to Benzenesulfonyl chloride, 3,4-dichloro- but with chlorine atoms attached at different positions on the benzene ring. This difference in substitution pattern can result in varying reactivity and properties compared to 3,4-dichloro-.
Another related compound is Benzenesulfonyl chloride, 3,5-dichloro-. Like the previous compounds mentioned, this compound features a benzene ring with sulfonyl chloride functional group attached, but with chlorine atoms positioned at different locations. The position of the chlorine atoms can impact the compound’s reactivity and selectivity in chemical reactions, making it important to consider when choosing a compound for specific applications.
Additionally, Benzenesulfonyl chloride, 2,3-dichloro- is another compound similar to Benzenesulfonyl chloride, 3,4-dichloro-. This compound shares the same sulfonyl chloride functional group attached to a benzene ring, with chlorine atoms located at different positions. Understanding the subtle differences between these compounds can be crucial in designing synthetic routes or selecting reagents for desired chemical transformations.
