1,8-Diazacyclotetradecane-2,9-dione is a compound commonly used in various industries such as pharmaceuticals, cosmetics, and agriculture. Its relevance in everyday life lies in its potential applications in drug development, skincare products, and pesticides. This compound’s unique chemical properties make it a valuable ingredient in the formulation of products that benefit human health, hygiene, and agricultural cultivation. Thus, 1,8-Diazacyclotetradecane-2,9-dione plays a crucial role in enhancing the quality of life for individuals worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,8-Diazacyclotetradecane-2,9-dione, commonly known as DABCO, has several commercial and industrial applications. It is often used as a catalyst in various chemical reactions, particularly in the production of polyurethane foams and coatings. DABCO is also utilized as a blowing agent in the manufacture of polyurethane foam insulation and as a stabilizer for PVC products.
In the realm of drug and medication applications, 1,8-Diazacyclotetradecane-2,9-dione has shown promise as a potential therapeutic agent. Research studies have demonstrated its potential efficacy in treating various diseases, such as cancer and viral infections. Its unique chemical properties make it a valuable candidate for drug development in the pharmaceutical industry.
As a versatile compound with diverse applications, 1,8-Diazacyclotetradecane-2,9-dione plays a crucial role in both commercial and industrial sectors. Its ability to function as a catalyst, blowing agent, and stabilizer makes it a valuable ingredient in the production of polyurethane foams, coatings, and PVC products. Additionally, its potential therapeutic properties make it an attractive candidate for drug development in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
1,8-Diazacyclotetradecane-2,9-dione is a white crystalline solid with a faint odor. Its appearance is similar to that of powdered sugar, and its odor is barely perceptible.
The molar mass of 1,8-Diazacyclotetradecane-2,9-dione is approximately 212.3 g/mol, and its density is around 1.1 g/cm³. This makes it similar in molar mass to glucose and in density to water.
1,8-Diazacyclotetradecane-2,9-dione has a melting point of approximately 190°C and a boiling point of around 425°C. These values are significantly higher than those of common household items like table salt and water.
This compound is sparingly soluble in water and has a high viscosity. Its solubility is comparable to that of olive oil, but its viscosity is closer to that of honey.
🏭 Production & Procurement
1,8-Diazacyclotetradecane-2,9-dione, also known as cyclam, is typically produced through the reaction of cyclen with formaldehyde in the presence of a base catalyst. This process results in the formation of a cyclic compound with 14 atoms, including two nitrogen atoms and a carbonyl group.
To procure 1,8-Diazacyclotetradecane-2,9-dione, one must first obtain cyclen, a commercially available compound commonly used as a starting material in the synthesis of cyclam. Once cyclen is obtained, it can be reacted with formaldehyde and a base catalyst to produce 1,8-Diazacyclotetradecane-2,9-dione. The final product can then be isolated and purified through standard chemical techniques.
Once produced, 1,8-Diazacyclotetradecane-2,9-dione can be transported in its solid form to various research laboratories or chemical manufacturing facilities. Due to its stable nature, cyclam can be safely transported using standard shipping methods, such as sealed containers or protective packaging, to ensure its integrity during transit. Overall, the production and procurement of 1,8-Diazacyclotetradecane-2,9-dione involve precise chemical reactions and careful handling to ensure the purity and quality of the final product.
⚠️ Safety Considerations
Safety considerations for 1,8-Diazacyclotetradecane-2,9-dione include proper storage to prevent contamination and degradation. It is important to handle the compound in a well-ventilated area to avoid inhalation of fumes. Personal protective equipment such as gloves, goggles, and lab coats should be worn when working with this chemical.
The pharmacology of 1,8-Diazacyclotetradecane-2,9-dione involves its ability to act as a chelating agent due to its macrocyclic structure containing two nitrogen atoms. This compound has been studied for its potential applications in metal ion extraction and catalysis. It is also being investigated for its bactericidal properties in various formulations.
Hazard statements for 1,8-Diazacyclotetradecane-2,9-dione include its potential for causing skin and eye irritation upon contact. This chemical may also be harmful if swallowed or inhaled, leading to respiratory irritation or other adverse effects. It is important to seek medical attention in case of exposure to this compound and to follow proper disposal procedures to prevent environmental contamination.
Precautionary statements for 1,8-Diazacyclotetradecane-2,9-dione recommend storing the chemical in a cool, dry place away from sources of ignition and incompatible materials. It is crucial to avoid contact with skin, eyes, and clothing when handling this compound and to wash hands thoroughly after use. In case of spills or leaks, appropriate cleanup procedures should be followed to minimize exposure and environmental impact.
🔬 Potential Research Directions
One potential research direction for 1,8-Diazacyclotetradecane-2,9-dione could explore its application as a chiral ligand in asymmetric catalysis. Studies may focus on the optimization of reaction conditions and substrate scope to achieve high enantioselectivity in various transformations.
Another avenue of research could involve investigating the coordination chemistry of 1,8-Diazacyclotetradecane-2,9-dione with transition metal ions. Understanding the coordination modes and stability constants of these complexes could provide insights into its potential as a metal ion sensor or catalyst for catalytic reactions.
Furthermore, research may delve into the design and synthesis of novel derivatives of 1,8-Diazacyclotetradecane-2,9-dione with modified structural features. These analogs could exhibit improved properties such as enhanced solubility, reactivity, or selectivity, leading to the development of more efficient and versatile molecular tools for various applications in organic synthesis and coordination chemistry.
🧪 Related Compounds
One similar compound to 1,8-Diazacyclotetradecane-2,9-dione is 1,4-Diazacyclohexane-2,5-dione, also known as succinimide. This compound shares a similar cyclic structure with 1,8-Diazacyclotetradecane-2,9-dione, but with a smaller ring size. Succinimide is commonly used in organic synthesis and pharmaceuticals due to its unique properties.
Another analogous compound is 1,3-Diazacyclopentane-2,4-dione, known as glutarimide. This compound also features a cyclic structure with two nitrogen atoms in the ring, similar to 1,8-Diazacyclotetradecane-2,9-dione. Glutarimide is utilized in a variety of applications, including as a monomer in polymer synthesis and as a precursor in the production of pharmaceuticals.
Furthermore, 1,5-Diazacycloheptane-2,6-dione, or piperazinedione, shares structural similarities with 1,8-Diazacyclotetradecane-2,9-dione. Piperazinedione is a heterocyclic compound that is often used in medicinal chemistry and as a building block in organic synthesis. Despite differences in ring size, both compounds exhibit similar reactivity patterns and can participate in similar chemical transformations.
