1-Hydroxycyclohexanecarbonitrile, a chemical compound used in various industries, plays a critical role in everyday life. It is commonly employed as a building block in the synthesis of pharmaceuticals, agrochemicals, and other important chemicals. Its versatile properties make it a valuable ingredient in the production of numerous consumer products, thus highlighting its significance in modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Hydroxycyclohexanecarbonitrile, also known as 2-Aminocyclohexanecarbonitrile, has found various commercial and industrial applications due to its unique chemical properties. It is commonly used as a precursor in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is also utilized in the production of organic compounds, such as amino acids and other derivatives.
In the pharmaceutical industry, 1-Hydroxycyclohexanecarbonitrile is employed in the synthesis of potential drug candidates and active pharmaceutical ingredients. It serves as a valuable building block in the development of new medications for a wide range of therapeutic applications. Additionally, it is utilized in medicinal chemistry research for the design and discovery of novel drug molecules with enhanced pharmacological properties.
Due to its versatile nature and compatibility with various chemical reactions, 1-Hydroxycyclohexanecarbonitrile plays a crucial role in the formulation of medications and pharmaceutical products. Its pharmaceutical applications extend to the synthesis of antibacterial agents, antiviral drugs, and anticancer therapies. Overall, the compound’s utility in drug development and medicinal chemistry highlights its significance in the healthcare and pharmaceutical sectors.
⚗️ Chemical & Physical Properties
1-Hydroxycyclohexanecarbonitrile is a white crystalline solid with a faint odor. The compound is typically described as odorless, but some may detect a slight chemical smell.
With a molar mass of 139.16 g/mol and a density of 1.11 g/cm³, 1-Hydroxycyclohexanecarbonitrile falls within the range of typical organic compounds in terms of molar mass and density. For comparison, common food items like sugar and salt have molar masses and densities that are similar to or slightly higher than that of 1-Hydroxycyclohexanecarbonitrile.
1-Hydroxycyclohexanecarbonitrile has a melting point of around 96-98°C and a boiling point of approximately 276-278°C. These values are within the range of melting and boiling points of many common food items, such as sugar and salt, which typically melt and boil at temperatures close to or higher than those of 1-Hydroxycyclohexanecarbonitrile.
1-Hydroxycyclohexanecarbonitrile is sparingly soluble in water and has a relatively low viscosity. This compound’s solubility in water and viscosity are similar to those of certain food items, such as oils and fats, which also exhibit limited solubility in water and lower viscosity compared to water-based liquids like milk or juice.
🏭 Production & Procurement
1-Hydroxycyclohexanecarbonitrile is typically produced through a multistep synthesis process starting with commercially available starting materials. The primary method involves the reaction of cyclohexanone with hydroxylamine hydrochloride to form the corresponding oxime. The oxime is then subjected to mild oxidation conditions to yield 1-Hydroxycyclohexanecarbonitrile.
The procurement of 1-Hydroxycyclohexanecarbonitrile can be achieved through reputable chemical suppliers who specialize in fine chemicals and intermediates. The compound is commonly available in both bulk quantities and smaller, research-grade quantities for laboratory use. Transportation of 1-Hydroxycyclohexanecarbonitrile is typically done in sealed containers to prevent spillage and contamination during transit.
When procuring 1-Hydroxycyclohexanecarbonitrile, it is essential to adhere to strict safety guidelines outlined by regulatory agencies to ensure proper handling and storage to prevent any accidents or environmental hazards. The compound should be stored in a cool, dry place away from direct sunlight and incompatible chemicals to maintain its stability and integrity. Proper labeling and documentation are also crucial for tracking and regulatory compliance when transporting 1-Hydroxycyclohexanecarbonitrile.
⚠️ Safety Considerations
Safety considerations for 1-Hydroxycyclohexanecarbonitrile should be taken seriously due to its potential hazards. This compound can cause skin irritation and may be harmful if swallowed or inhaled. It is also important to avoid contact with eyes and to wear appropriate protective equipment when handling this substance.
In addition to its physical hazards, 1-Hydroxycyclohexanecarbonitrile may pose environmental risks as well. It can be toxic to aquatic life and may have long-lasting effects on the ecosystem if released into waterways. Therefore, proper disposal methods should be followed to minimize environmental impact.
Overall, when working with 1-Hydroxycyclohexanecarbonitrile, it is essential to prioritize safety by following proper handling procedures, wearing protective gear, and taking steps to prevent exposure to this potentially hazardous compound.
The hazard statements for 1-Hydroxycyclohexanecarbonitrile include “Causes skin irritation” and “Harmful if swallowed or inhaled.” These statements indicate the potential dangers associated with this compound and emphasize the importance of taking precautions when handling it. It is crucial to be aware of these hazards and to follow proper safety protocols to prevent harm.
Precautionary statements for 1-Hydroxycyclohexanecarbonitrile include “Avoid contact with skin and eyes,” “Wear protective gloves/eye protection/face protection,” and “Dispose of contents/container in accordance with local/regional/national/international regulations.” These statements highlight the necessary precautions that should be taken when working with this compound to minimize the risk of harm. Following these guidelines can help ensure the safe handling and use of 1-Hydroxycyclohexanecarbonitrile.
🔬 Potential Research Directions
Research on 1-Hydroxycyclohexanecarbonitrile may explore its potential applications in organic synthesis, specifically as a versatile building block for the preparation of various compounds. Studies could investigate the reaction mechanisms involved in the transformation of 1-Hydroxycyclohexanecarbonitrile into different functional groups, expanding its synthetic utility.
Furthermore, investigations into the pharmaceutical properties of 1-Hydroxycyclohexanecarbonitrile could be conducted to evaluate its potential as a drug candidate. Research may focus on the biological activities exhibited by this compound and its derivatives, paving the way for the development of new therapeutic agents for various medical conditions.
Additionally, studies could delve into the environmental impact of 1-Hydroxycyclohexanecarbonitrile and its derivatives to assess their toxicity and biodegradability. Research in this area could provide valuable insights into the ecological consequences of the widespread use of this compound and guide the development of eco-friendly alternatives in chemical processes.
🧪 Related Compounds
1-Hydroxycyclohexanecarbonitrile is a compound with a molecular structure that consists of a cyclohexane ring with a hydroxyl group attached to carbon 1 and a nitrile group attached to carbon 2. Similar compounds can be identified based on variations in substituents or functional groups attached to the cyclohexane ring.
One similar compound is 1-Methylcyclohexanecarbonitrile, where a methyl group is attached to carbon 1 of the cyclohexane ring instead of a hydroxyl group. This compound shares the same carbonitrile moiety as 1-Hydroxycyclohexanecarbonitrile but differs in the presence of a methyl group instead of a hydroxyl group.
Another similar compound is 1-Hydroxycyclohexanecarboxylic acid, where a carboxylic acid group is attached to carbon 1 of the cyclohexane ring instead of a nitrile group. This compound shares the presence of a hydroxyl group at carbon 1 with 1-Hydroxycyclohexanecarbonitrile but differs in the functional group attached at carbon 2.
A third similar compound is 1-Ethylcyclohexanecarbonitrile, where an ethyl group is attached to carbon 1 of the cyclohexane ring instead of a hydroxyl group. This compound shares the same carbonitrile moiety as 1-Hydroxycyclohexanecarbonitrile but differs in the presence of an ethyl group instead of a hydroxyl group.
