Indene, a bicyclic aromatic hydrocarbon, holds significance in everyday life due to its application in the production of various commodities. It is utilized in the manufacturing of plastics, resins, and adhesives, consequently contributing to the creation of a wide array of consumer products. Additionally, indene is employed in the synthesis of pharmaceuticals and as a precursor in the production of fragrances and flavors. Thus, the versatility of indene plays a pivotal role in shaping numerous aspects of modern living.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Indene, a bicyclic aromatic hydrocarbon, has several commercial and industrial applications. It is used as a starting material in the production of synthetic resins and high-performance polymers, such as indene-coumarone resins and indene-styrene copolymers. Indene is also utilized in the manufacturing of fuel additives, lubricants, and coatings due to its high reactivity and stability.
In the realm of drug and medication applications, indene has garnered attention for its potential therapeutic properties. Research suggests that indene derivatives may possess anti-cancer, anti-inflammatory, and antimicrobial activities, making them attractive candidates for drug development. In addition, indene-based compounds have shown promise in the treatment of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, due to their ability to target specific biological pathways. Despite these potential benefits, further studies are needed to fully explore the medicinal properties of indene in clinical settings.
⚗️ Chemical & Physical Properties
Indene is a colorless liquid with a strong aromatic odor. It is commonly used in the production of plastics and as a starting material in organic synthesis.
With a molar mass of 116.19 g/mol and a density of 0.98 g/cm3, indene is lighter than common household items such as water (molar mass 18 g/mol, density 1 g/cm3) and iron (molar mass 56 g/mol, density 7.87 g/cm3).
Indene has a melting point of -53.6°C and a boiling point of 180.4°C. Compared to common household items like butter (melting point 32°C, boiling point 177°C), indene has a lower melting point but a higher boiling point.
Indene is slightly soluble in water and has a low viscosity. Compared to common household items like sugar (soluble in water, high viscosity), indene’s solubility and viscosity are relatively low.
🏭 Production & Procurement
Indene is primarily produced through the thermal cracking of naphtha, a product obtained during the refinement of crude oil. This process involves subjecting naphtha to high temperatures, leading to the formation of various aromatic hydrocarbons, including Indene.
Indene can be procured from chemical suppliers or manufacturers specialized in the production of aromatic compounds. It is commonly transported in either liquid or solid form, depending on the specific needs of the end user. Transporting Indene typically involves the use of specialized containers or tanker trucks to ensure its safe and secure delivery.
When procuring Indene, considerations must be made for its handling and storage requirements, as it is a flammable substance with potential health hazards. Companies involved in the procurement and transportation of Indene must adhere to strict safety regulations to prevent accidents and ensure the well-being of personnel and surrounding communities.
⚠️ Safety Considerations
Safety considerations for Indene should be taken seriously due to its potential health hazards. Exposure to Indene can irritate the respiratory system, skin, and eyes. Prolonged or repeated exposure may lead to more serious health effects. It is important to handle Indene with proper protective equipment and in a well-ventilated area to minimize the risk of exposure.
Indene is a polycyclic aromatic hydrocarbon with a chemical structure consisting of a cyclopentadiene ring fused to a benzene ring. It has a molecular formula of C9H8 and a molecular weight of 116.16 g/mol. The pharmacology of Indene is not well-defined, as it is primarily used in chemical synthesis and industrial applications rather than pharmaceuticals. Studies on the pharmacological effects of Indene are limited, but its potential hazards are well-documented.
The hazard statements for Indene include “Harmful if swallowed,” “Causes skin irritation,” and “May cause respiratory irritation.” Indene is also classified as a flammable liquid and vapor, posing a fire hazard. It is important to handle Indene with caution, as improper storage or handling can result in serious health and safety risks. It is recommended to store Indene in a cool, well-ventilated area away from heat or ignition sources to prevent accidents.
Precautionary statements for Indene include “Do not breathe dust/fume/gas/mist/vapors/spray,” “Wash thoroughly after handling,” and “Use only outdoors or in a well-ventilated area.” It is important to use appropriate personal protective equipment, such as gloves and safety glasses, when working with Indene to prevent skin contact and eye irritation. In case of accidental exposure, seek medical attention immediately and provide the medical personnel with information about the substance. Proper handling and storage of Indene are essential to minimize the risks associated with its use.
🔬 Potential Research Directions
One potential research direction for Indene relates to its use as a building block in the synthesis of various pharmaceuticals and agrochemicals. The unique structural features of Indene make it a valuable starting material for the creation of new compounds with diverse biological activities.
Another promising area of investigation involves the study of Indene derivatives as potential materials for organic electronics. The electronic properties of Indene-based compounds can be fine-tuned through structural modification, offering opportunities for the development of novel electronic devices with improved performance.
Furthermore, research on the environmental impact and toxicology of Indene and its derivatives is a critical area of concern. Understanding the potential risks associated with the use and disposal of these compounds is essential for ensuring their safe and sustainable application in various industrial processes.
🧪 Related Compounds
One similar compound to Indene based on its molecular structure is Indole. Indole is a heterocyclic aromatic organic compound with a bicyclic structure containing a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It is commonly found in various natural products and is a key structural element in many biologically active molecules.
Another compound similar to Indene is Naphthalene. Naphthalene is a polycyclic aromatic hydrocarbon that consists of two benzene rings fused together. While it is structurally different from Indene due to the presence of an additional benzene ring, it shares a similar aromatic character and stability. Naphthalene is commonly used as a moth repellent and in the production of dyes and resins.
Benzofuran is also a compound with a molecular structure similar to Indene. Benzofuran is a heterocyclic compound composed of a benzene ring fused to a furan ring. Like Indene, benzofuran exhibits aromaticity and is used in various applications, including as a building block in the synthesis of pharmaceuticals and agrochemicals. Benzofuran derivatives have shown potential as neuroprotective agents and anticancer drugs.
