Quinoline-2-carboxylic acid, a compound derived from quinoline, plays a critical role in the pharmaceutical industry as a key component in the synthesis of various drugs and medications. Its relevance extends to everyday life as it is utilized in the production of anti-malarial and antiviral medications, as well as in the development of treatments for conditions such as tuberculosis and cancer. Additionally, quinoline-2-carboxylic acid is a significant component in the creation of pesticides and herbicides, contributing to agricultural practices and food production. The compound’s versatile applications highlight its importance in modern society and underscore its impact on various aspects of daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Quinoline-2-carboxylic acid, also known as 2-quinolinecarboxylic acid, is utilized in various commercial and industrial applications. This compound is commonly used in the synthesis of pharmaceuticals, agrochemicals, and dyes due to its versatile chemical properties. Additionally, quinoline-2-carboxylic acid serves as a building block for the production of complex organic molecules in the pharmaceutical and fine chemical industries.
In terms of drug and medication applications, quinoline-2-carboxylic acid plays a crucial role in the development of certain drugs. It serves as a precursor for the synthesis of antimalarial medications such as chloroquine and quinine, which have been widely used for the treatment of malaria. Furthermore, this compound is employed in the production of quinolone antibiotics, which are used to treat a variety of bacterial infections in the medical field.
Overall, quinoline-2-carboxylic acid demonstrates significant commercial and industrial value due to its diverse applications in pharmaceutical, agrochemical, and dye industries. Its role in the synthesis of essential drugs and medications underscores its importance in the healthcare sector, further highlighting its significance in various fields of science and technology.
⚗️ Chemical & Physical Properties
Quinoline-2-carboxylic acid is a white crystalline solid with a faint odor. It is slightly soluble in water and has a distinct chemical structure that gives it its unique properties.
The molar mass of Quinoline-2-carboxylic acid is approximately 159.16 g/mol, with a density of around 1.351 g/cm3. Compared to common household items, it has a relatively low molar mass but a higher density, making it a more compact substance.
Quinoline-2-carboxylic acid has a melting point of about 333 °C and a boiling point of approximately 379 °C. These values are significantly higher than those of common household items, indicating that it is more heat-resistant.
In terms of solubility in water, Quinoline-2-carboxylic acid is sparingly soluble, and it exhibits moderate viscosity. Compared to common household items, it has a lower solubility but a similar viscosity, making it less likely to dissolve easily in water.
🏭 Production & Procurement
Quinoline-2-carboxylic acid is typically produced through the oxidation of quinoline using various methods, such as nitric acid or potassium permanganate. This chemical reaction results in the formation of Quinoline-2-carboxylic acid as the final product.
Once Quinoline-2-carboxylic acid is produced, it can be procured from chemical suppliers or manufacturers. It is commonly transported in sealed containers or drums to prevent any contamination or leakage during transit. Proper labeling and documentation are essential for the safe and secure transportation of Quinoline-2-carboxylic acid.
Additionally, Quinoline-2-carboxylic acid can also be synthesized in laboratories using specific chemical procedures and techniques. Researchers and scientists may produce small quantities of Quinoline-2-carboxylic acid for experimental purposes or pharmaceutical applications. It is crucial to follow strict safety protocols and guidelines when handling and storing Quinoline-2-carboxylic acid to prevent any accidents or chemical hazards.
⚠️ Safety Considerations
Safety considerations for Quinoline-2-carboxylic acid include its potential for skin and eye irritation. It is important to handle this compound with care, wearing appropriate personal protective equipment such as gloves and goggles. In case of contact with skin or eyes, it is advised to rinse thoroughly with water and seek medical attention if irritation persists.
In terms of pharmacology, Quinoline-2-carboxylic acid is a heterocyclic compound with potential biological activity. It has been studied for its antimicrobial properties and may have potential therapeutic applications in the treatment of bacterial infections. Further research is needed to fully understand its pharmacological effects and mechanisms of action.
Hazard statements for Quinoline-2-carboxylic acid include its classification as a skin and eye irritant. It may also be harmful if swallowed, inhaled, or absorbed through the skin. This compound should be stored and handled according to strict safety guidelines to minimize the risk of exposure and potential health hazards.
Precautionary statements for Quinoline-2-carboxylic acid emphasize the importance of avoiding direct contact with the compound. It should be stored in a cool, dry place away from sources of ignition and incompatible materials. Proper ventilation and personal protective equipment should be used when handling this compound to prevent exposure and ensure safe working conditions.
🔬 Potential Research Directions
Potential research directions for Quinoline-2-carboxylic acid may focus on its pharmacological properties, particularly its role as a precursor for the synthesis of various pharmaceutical compounds. Studies could investigate the interactions of Quinoline-2-carboxylic acid with biological targets and evaluate its potential as a therapeutic agent.
Furthermore, research efforts could explore the chemical reactivity of Quinoline-2-carboxylic acid and its derivatives, with a focus on developing efficient synthetic methods for their preparation. This could involve the design and optimization of new reactions that utilize Quinoline-2-carboxylic acid as a key building block, aiming to streamline the synthesis of valuable compounds for pharmaceutical and materials science applications.
Additionally, investigations into the environmental impact of Quinoline-2-carboxylic acid and its derivatives could be a potential research direction. This could include studying their degradation pathways, assessing their persistence in the environment, and developing strategies for their environmental remediation. Understanding the fate and transport of Quinoline-2-carboxylic acid in different environmental matrices could provide valuable insights for mitigating potential risks associated with its use.
🧪 Related Compounds
One similar compound to Quinoline-2-carboxylic acid based upon molecular structure is Isoquinoline-5-carboxylic acid. This compound shares a similar heterocyclic ring system with Quinoline-2-carboxylic acid, but with a different substitution pattern on the nitrogen atom. Isoquinoline-5-carboxylic acid is commonly used in organic chemistry research and pharmaceutical development.
Another compound with a structural similarity to Quinoline-2-carboxylic acid is Quinaldic acid. This compound contains a quinoline ring system with a carboxylic acid functional group at the 4-position. Quinaldic acid has been utilized in the synthesis of various heterocyclic compounds and as a building block for the preparation of pharmaceutical agents.
A third compound similar in structure to Quinoline-2-carboxylic acid is Pyridine-2-carboxylic acid. While Pyridine-2-carboxylic acid lacks the fused ring system of quinoline, it shares a carboxylic acid functional group attached to a nitrogen-containing heterocyclic ring. Pyridine-2-carboxylic acid is a common intermediate in organic synthesis and is widely studied due to its versatile reactivity.
