2-Naphthoic acid, a chemical compound derived from naphthalene, is of relevance to everyday life due to its use in the production of dyes, pigments, and pharmaceuticals. This compound is commonly employed in the textile industry for dyeing fabrics, in the creation of colorful pigments for paints, and in the development of various medications. The versatility of 2-Naphthoic acid in these applications highlights its significance in enhancing aesthetics, preserving cultural heritage through color preservation, and advancing healthcare through the production of pharmaceuticals.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Naphthoic acid, also known as β-naphthoic acid, has several commercial and industrial applications. It is commonly used in the production of dyes, pigments, and fluorescent brighteners for textiles and plastics. Additionally, 2-Naphthoic acid is utilized in the manufacturing of pharmaceuticals, antioxidants, and other specialty chemicals.
In the realm of drug and medication applications, 2-Naphthoic acid plays a significant role. It is a key intermediate in the synthesis of various pharmaceutical compounds, including anti-inflammatory drugs and antimicrobial agents. Moreover, 2-Naphthoic acid is utilized in the formulation of topical medications for skin disorders and in the production of vitamin supplements.
Overall, 2-Naphthoic acid’s versatile properties make it a valuable compound in both commercial and industrial sectors. Its applications range from dye production to pharmaceutical synthesis, highlighting its importance in various industries. Additionally, its role in drug formulation underscores its significance in the healthcare and pharmaceutical fields.
⚗️ Chemical & Physical Properties
2-Naphthoic acid, also known as β-naphthoic acid, appears as a white to pale yellow crystalline powder with a faint odor. Its distinctive aromatic scent is often described as slightly musty or phenolic in nature.
The molar mass of 2-Naphthoic acid is approximately 172.20 g/mol, with a density of about 1.31 g/cm³. In comparison to common household items, 2-Naphthoic acid has a higher molar mass than table salt (NaCl) and a lower density than honey.
2-Naphthoic acid possesses a melting point of around 140-142°C and a boiling point of approximately 357°C. These values are higher than those of water (melting point of 0°C, boiling point of 100°C) but lower than those of iron (melting point of 1538°C, boiling point of 2861°C).
2-Naphthoic acid is sparingly soluble in water, but readily soluble in organic solvents like ethanol and acetone. It exhibits moderate viscosity, which is similar to that of vegetable oil but lower than that of honey.
🏭 Production & Procurement
2-Naphthoic acid, commonly known as β-naphthoic acid, is primarily produced through the oxidation of 2-naphthalenethiol. This process typically involves the use of oxidizing agents such as potassium permanganate or chromic acid to convert the thiol group into a carboxylic acid group.
The procurement of 2-Naphthoic acid can be accomplished through various means, including direct purchase from chemical suppliers or synthesis in a laboratory setting. Once obtained, the compound may be stored and transported in sealed containers to prevent oxidation or degradation during transit.
When procuring 2-Naphthoic acid, it is essential to adhere to proper safety protocols and handling procedures due to its potential toxicity and harmful effects if not handled correctly. Careful consideration should be given to the mode of transport and storage conditions to ensure the integrity of the compound is maintained throughout the procurement process.
⚠️ Safety Considerations
Safety considerations for 2-Naphthoic acid include proper handling and storage to avoid exposure. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with this compound. In case of skin contact, wash the affected area with soap and water immediately. If inhalation or ingestion occurs, seek medical attention promptly.
The pharmacology of 2-Naphthoic acid involves its potential as an anti-inflammatory and antioxidant agent. Studies have shown that this compound may have therapeutic effects in conditions such as inflammation and oxidative stress-related diseases. Its mechanism of action is thought to involve modulation of inflammatory pathways and scavenging of free radicals.
Hazard statements for 2-Naphthoic acid include causes skin and eye irritation. This compound may also be harmful if swallowed or inhaled. It is important to avoid direct contact with the substance and to use appropriate protective measures when handling it. In case of exposure, seek medical advice immediately and provide details of the incident.
Precautionary statements for 2-Naphthoic acid include wearing protective gloves and eye protection when handling the compound. Ensure adequate ventilation in the workspace to prevent inhalation of vapors or dust. Store the substance in a tightly closed container in a cool, dry place away from incompatible materials. In case of spills, clean up promptly and dispose of waste in accordance with local regulations.
🔬 Potential Research Directions
One potential research direction for 2-Naphthoic acid is its role as a biosynthetic precursor in the production of various pharmaceutical compounds. Studies could explore the enzymatic pathways involved in the conversion of 2-Naphthoic acid into biologically active molecules, as well as its potential as a starting material for the synthesis of new drugs.
Another area of interest could be the investigation of the biological activities of 2-Naphthoic acid and its derivatives. Research could focus on the anti-inflammatory, antioxidant, or antimicrobial properties of this compound, and how structural modifications can influence its bioactivity. Understanding the pharmacological potential of 2-Naphthoic acid could lead to the development of novel therapeutic agents with improved efficacy and reduced side effects.
Furthermore, studies could explore the environmental fate and toxicological effects of 2-Naphthoic acid. Research in this area could involve investigating its persistence in the environment, potential for bioaccumulation in living organisms, and adverse effects on human health and ecosystems. By examining the environmental behavior and toxicity of 2-Naphthoic acid, researchers can better assess its risk to human and environmental health.
🧪 Related Compounds
One similar compound to 2-Naphthoic acid based upon molecular structure is 1-Naphthoic acid, which differs only in the position of the carboxylic acid group. In 1-Naphthoic acid, the carboxylic acid group is attached at the first position of the naphthalene ring, as opposed to the second position in 2-Naphthoic acid. Despite this difference in placement, both compounds share many similar chemical and physical properties due to their close structural relationship.
Another similar compound to 2-Naphthoic acid is 2-Naphthalene carboxylic acid, which is a structural isomer. In 2-Naphthalene carboxylic acid, the carboxylic acid group is positioned on the same ring as in 2-Naphthoic acid, but on a different carbon atom. This variation in the location of the carboxylic acid group results in distinctive chemical properties between 2-Naphthoic acid and 2-Naphthalene carboxylic acid, despite their structural similarities.
