3-Bromopyridine is a chemical compound that is commonly used in the pharmaceutical industry for the synthesis of various drugs, including anti-inflammatory agents, antifungal medications, and cardiovascular drugs. Despite its somewhat obscure nature, 3-Bromopyridine plays a crucial role in the development of life-saving medications that millions of people rely on every day. Thus, its significance in everyday life cannot be understated.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
3-Bromopyridine, a halogenated derivative of pyridine, is commonly utilized in commercial and industrial applications. It is often used as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. 3-Bromopyridine is also a key intermediate in the production of herbicides, insecticides, and fungicides.
In drug and medication applications, 3-Bromopyridine plays a crucial role in the development of various pharmaceuticals. It is widely used in the synthesis of molecules for antiviral, antibacterial, and anticancer drugs. Additionally, 3-Bromopyridine is utilized as a synthetic precursor in the production of active pharmaceutical ingredients for therapeutic purposes.
The versatility of 3-Bromopyridine makes it a valuable compound in both commercial and pharmaceutical industries. Its unique chemical properties enable its use in a wide range of applications, highlighting its importance as a building block for diverse products. Whether in the development of new drugs or the production of specialty chemicals, 3-Bromopyridine continues to be a vital component in various industrial processes.
⚗️ Chemical & Physical Properties
3-Bromopyridine is a colorless liquid with a sharp, irritating odor. It is commonly used as a building block in the synthesis of pharmaceutical or agrochemical products.
With a molar mass of 156.98 g/mol and a density of 1.59 g/cm³, 3-Bromopyridine is heavier than common food items such as water or vinegar. Its density makes it more compact and less likely to float on the surface of liquids.
3-Bromopyridine has a melting point of -22°C and a boiling point of 145-147°C. Compared to common food items like chocolate or sugar, it has a much lower melting point and higher boiling point, making it a more volatile substance.
This compound is sparingly soluble in water, but highly soluble in organic solvents. It has a low viscosity, meaning it flows easily. In comparison to common food items like salt or flour, which are readily soluble in water and have a higher viscosity, 3-Bromopyridine behaves differently in terms of solubility and viscosity.
🏭 Production & Procurement
3-Bromopyridine is typically produced through the bromination of pyridine. This chemical reaction involves the addition of a bromine atom to the pyridine molecule, resulting in the formation of 3-Bromopyridine. The reaction is carried out using a brominating agent, such as hydrogen bromide or bromine, in the presence of a catalyst.
Once 3-Bromopyridine is produced, it can be procured from chemical suppliers and manufacturers. The compound is commonly available in both small-scale and bulk quantities for research and industrial purposes. 3-Bromopyridine can be transported in various forms, such as liquid solution or solid crystals, depending on the specific requirements of the end user.
When procuring 3-Bromopyridine, it is important to ensure that proper safety precautions are taken during handling and transportation. The compound can be hazardous if not handled correctly, and appropriate measures should be taken to minimize any risks associated with its use. Additionally, proper storage conditions should be maintained to prevent degradation or contamination of the product.
⚠️ Safety Considerations
Safety Considerations for 3-Bromopyridine:
When handling 3-Bromopyridine, it is imperative to wear appropriate personal protective equipment, including gloves, protective clothing, and goggles, to prevent skin contact, inhalation, and eye exposure. Additionally, it is essential to work in a well-ventilated area or use a fume hood to minimize the risk of inhaling the compound’s vapors. Furthermore, ensure proper storage of 3-Bromopyridine in a cool, dry place away from heat, sources of ignition, and incompatible materials to prevent accidents or chemical reactions.
Hazard Statements for 3-Bromopyridine:
3-Bromopyridine may cause skin and eye irritation upon contact and may be harmful if inhaled or ingested. It is also suspected of causing genetic defects and may have adverse effects on aquatic organisms. This compound should be handled with caution to prevent harm to human health and the environment. Adequate safety measures and personal protective equipment should be used when working with 3-Bromopyridine to minimize the risk of exposure.
Precautionary Statements for 3-Bromopyridine:
When working with 3-Bromopyridine, avoid breathing its vapors, mist, or dust and avoid skin and eye contact. In case of contact, rinse thoroughly with water and seek medical attention if irritation persists. Store 3-Bromopyridine in a tightly closed container in a well-ventilated area and keep it away from incompatible materials. Dispose of any unused or contaminated product according to local regulations. It is crucial to follow proper handling procedures and safety precautions to prevent accidents and ensure the safe use of 3-Bromopyridine.
🔬 Potential Research Directions
One potential research direction for 3-Bromopyridine is its use as a building block in organic synthesis. Its unique structure and reactivity make it a valuable intermediate for the preparation of various functionalized pyridine derivatives.
Furthermore, 3-Bromopyridine may also be investigated for its potential biological activities. Studies could focus on its interactions with biological targets or its potential as a pharmaceutical agent. This research could lead to the development of new drug candidates with improved efficacy and reduced side effects.
Additionally, the development of new synthetic methodologies involving 3-Bromopyridine could be explored. This could include the investigation of novel catalytic processes or the design of more efficient synthetic routes for accessing complex pyridine-containing compounds. Such research could contribute to the advancement of synthetic organic chemistry.
🧪 Related Compounds
One similar compound to 3-Bromopyridine based upon molecular structure is 2-Bromopyridine. This compound is structurally similar to 3-Bromopyridine, with the bromine atom located in the 2-position of the pyridine ring. Like 3-Bromopyridine, 2-Bromopyridine is commonly used as a building block in organic synthesis.
Another compound that shares a similar structure to 3-Bromopyridine is 4-Bromopyridine. In this compound, the bromine atom is situated in the 4-position of the pyridine ring. 4-Bromopyridine also finds applications in organic synthesis, much like its 3- and 2- counterparts.
Additionally, 2,3-Bromopyridine is another compound that bears resemblance to 3-Bromopyridine in terms of molecular structure. In this compound, the bromine atoms are present at both the 2- and 3-positions of the pyridine ring. 2,3-Bromopyridine can exhibit unique reactivity due to the presence of two bromine atoms in the molecule, making it a versatile building block in organic chemistry.
