N-Methylacetanilide, a compound often used in the production of pharmaceuticals and pesticides, plays a crucial role in everyday life. It serves as a key building block in the synthesis of various medications that are essential for treating numerous medical conditions, as well as in the creation of pesticides that help protect crops from pests and diseases. Its versatility and widespread application make it a significant component in the pharmaceutical and agricultural industries, ultimately impacting the health and well-being of individuals and the global food supply.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-Methylacetanilide, also known as N-methyl-N-phenylacetamide, has several commercial and industrial applications. It is commonly used as an intermediate in the manufacturing of various pharmaceuticals, dyes, and other organic compounds. N-Methylacetanilide is also utilized in the production of pesticides and rubber chemicals due to its unique chemical properties.
In the realm of drug and medication applications, N-Methylacetanilide plays a crucial role as an intermediate in the synthesis of analgesics and anti-inflammatory drugs. Its chemical structure allows for the modification and enhancement of pharmacological properties, making it a valuable component in the pharmaceutical industry. Additionally, N-Methylacetanilide serves as a key building block in the creation of various health products and medications that target specific medical conditions.
⚗️ Chemical & Physical Properties
N-Methylacetanilide is a white crystalline solid with a faint amine-like odor. It appears as a fine powder or small crystals, and has a slight solubility in water but is more soluble in organic solvents.
The molar mass of N-Methylacetanilide is approximately 165.2 g/mol, and its density is around 1.1 g/cm3. This puts it in the range of many common food items in terms of molar mass and density, such as sugar or salt.
N-Methylacetanilide has a melting point of around 100-105°C and a boiling point of approximately 307°C. These temperatures are higher than those of most common food items, such as butter or chocolate, which have lower melting and boiling points.
N-Methylacetanilide is sparingly soluble in water, but more soluble in organic solvents. It has a low viscosity, making it flow easily. This differs from many common food items, which are typically more soluble in water and have higher viscosities.
🏭 Production & Procurement
N-Methylacetanilide, also known as N-Methyl-N-phenylacetamide, is typically produced through the reaction of N-methylaniline with acetic anhydride in the presence of a catalyst such as sulfuric acid. This reaction results in the formation of N-Methylacetanilide along with acetic acid as a byproduct.
N-Methylacetanilide can be procured through chemical supply companies that specialize in fine chemicals and pharmaceutical intermediates. It is often transported in sealed containers to prevent contamination and ensure its stability during transit. Due to its use as a precursor in the synthesis of various pharmaceuticals and agrochemicals, N-Methylacetanilide is considered a valuable compound in the chemical industry.
Although N-Methylacetanilide can be synthesized in a laboratory setting, commercial production offers a more efficient and cost-effective means of obtaining this compound in larger quantities. The procurement of N-Methylacetanilide is subject to regulatory requirements, including proper labeling, handling, and storage to ensure safety and compliance with industry standards. Overall, the production and procurement of N-Methylacetanilide play a crucial role in the pharmaceutical and chemical industries.
⚠️ Safety Considerations
Safety considerations for N-Methylacetanilide include its potential for skin and eye irritation. It is also classified as a potential reproductive toxicant and may cause harm if ingested or inhaled. Proper personal protective equipment, such as gloves and goggles, should be worn when handling this chemical to minimize the risk of exposure.
Hazard statements for N-Methylacetanilide include “Causes skin irritation” and “Causes serious eye irritation.” It is also classified as a Category 2 reproductive toxicant, meaning it may cause harm to fertility or the unborn child. Exposure to this chemical should be avoided, and proper precautions should be taken to prevent skin and eye contact.
Precautionary statements for N-Methylacetanilide include “Avoid breathing dust/fume/gas/mist/vapors/spray,” “Wear protective gloves/protective clothing/eye protection/face protection,” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.” It is important to follow these guidelines to minimize the risk of exposure and potential health effects associated with this chemical.
🔬 Potential Research Directions
One potential research direction for N-Methylacetanilide is the study of its potential pharmaceutical applications. Researchers may investigate the compound’s efficacy as a drug candidate for treating various medical conditions.
Another area of interest could be the investigation of N-Methylacetanilide’s chemical properties and reactivity. By examining its structure and behavior under different conditions, scientists may uncover new insights into its potential uses in organic synthesis or material science.
Furthermore, the toxicological profile of N-Methylacetanilide could be the focus of research, with the aim of understanding its safety and potential health risks. Studies on its metabolism, distribution, and potential adverse effects could provide valuable information for risk assessment and regulatory purposes.
🧪 Related Compounds
One similar compound to N-Methylacetanilide based upon molecular structure is N-Ethylacetanilide. In this compound, the methyl group of N-Methylacetanilide is replaced with an ethyl group. This substitution results in a compound with similar chemical properties but with a slightly larger alkyl group attached to the nitrogen atom.
Another related compound is N-Propylacetanilide. In this compound, the methyl group of N-Methylacetanilide is replaced with a propyl group. Like N-Ethylacetanilide, this substitution results in a compound with a larger alkyl group attached to the nitrogen atom, which may impact its chemical reactivity and properties.
A third related compound is N-Benzylacetanilide. In this compound, the methyl group of N-Methylacetanilide is replaced with a benzyl group. The addition of a benzyl group results in a compound with a bulkier substituent attached to the nitrogen atom, which can influence its solvent compatibility and biological activity.
