N-Hydroxybenzamide is a compound that is of particular interest in various industries due to its versatility in chemical synthesis and potential applications. Its relevance to everyday life lies in its use as a key ingredient in the production of pharmaceuticals, agrochemicals, and personal care products. Furthermore, N-Hydroxybenzamide has shown promise in research related to combating various diseases, making it a compound of significant importance in the realm of science and innovation.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
N-Hydroxybenzamide is a compound primarily utilized in commercial and industrial applications for its utility as a stabilizer and polymer additive. It is commonly used in the production of certain plastics and rubber products to increase their durability and resistance to degradation. In addition, N-Hydroxybenzamide is also employed in the manufacturing of adhesives, coatings, and sealants due to its ability to enhance the adhesive properties of these materials.
In drug and medication applications, N-Hydroxybenzamide has been investigated for its potential therapeutic effects in treating various medical conditions. Studies have shown that this compound possesses anti-inflammatory properties, making it a promising candidate for the development of new anti-inflammatory drugs. Furthermore, N-Hydroxybenzamide has been explored for its potential antitumor activity, with research suggesting that it may inhibit the growth of cancer cells and help in the treatment of certain types of cancer.
⚗️ Chemical & Physical Properties
N-Hydroxybenzamide is a white crystalline solid that has a faint odor. It appears as fine crystals and does not have a distinct smell.
With a molar mass of approximately 151.15 g/mol and a density of around 1.34 g/cm³, N-Hydroxybenzamide is heavier than common food items like sugar (180.16 g/mol, 1.59 g/cm³) and salt (58.44 g/mol, 2.16 g/cm³).
N-Hydroxybenzamide has a melting point of about 134°C and a boiling point of around 330°C. These values are significantly higher than those of common food items like butter (melting point of 32-35°C, boiling point above 100°C) and chocolate (melting point of approximately 34°C, boiling point above 100°C).
N-Hydroxybenzamide is sparingly soluble in water and has a low viscosity. This differs from common food items like sugar and salt, which have high solubility in water and honey, which has a high viscosity.
🏭 Production & Procurement
N-Hydroxybenzamide, a compound with various industrial applications, is primarily produced through the reaction between benzoyl chloride and hydroxylamine. This process involves the addition of hydroxylamine to benzoyl chloride under controlled conditions to yield N-Hydroxybenzamide.
To procure N-Hydroxybenzamide, one must typically work with specialized chemical suppliers or manufacturers. These entities have the expertise and equipment necessary for the safe production and handling of chemical compounds like N-Hydroxybenzamide. Once obtained, the compound can be securely packaged and transported in specialized containers to prevent contamination or degradation.
Transporting N-Hydroxybenzamide should be done in compliance with regulations regarding the transportation of hazardous materials. Secure packaging, specialized containers, and proper labeling are essential to ensure the safe transportation of N-Hydroxybenzamide. Additionally, working with reputable carriers experienced in handling chemical compounds is crucial to prevent accidents and ensure the integrity of the compound during transport.
⚠️ Safety Considerations
Safety considerations for N-Hydroxybenzamide include its potential to cause skin and eye irritation upon contact. Inhaling or ingesting the substance may also result in respiratory irritation and other health effects. It is important to handle this chemical with care, using appropriate protective equipment such as gloves and goggles, and to work with it in a well-ventilated area to minimize exposure and risk.
Hazard statements for N-Hydroxybenzamide include its classification as a skin irritant and eye irritant. It is also labeled as harmful if swallowed or if inhaled. These statements indicate the potential dangers associated with this chemical and the importance of taking precautions to avoid exposure to it.
Precautionary statements for N-Hydroxybenzamide include wearing protective gloves and eye protection when handling the substance to prevent skin and eye irritation. It is recommended to work with this chemical in a fume hood or well-ventilated area to minimize inhalation exposure. In case of accidental exposure, it is advised to seek medical attention and provide the medical personnel with the safety data sheet for N-Hydroxybenzamide.
🔬 Potential Research Directions
Research on N-Hydroxybenzamide has shown promising potential as a precursor for the synthesis of a wide range of organic compounds. Further investigation into its reactivity and selectivity in various chemical reactions may lead to the discovery of novel synthetic methods and applications in organic chemistry.
Its unique structure and properties suggest that N-Hydroxybenzamide may exhibit interesting biological activities. Studies focused on its interaction with enzymes, receptors, and other biological targets could provide valuable insights into its potential as a pharmaceutical agent or a lead compound for drug discovery.
Exploring the potential of N-Hydroxybenzamide in materials science may uncover new opportunities for the development of functional materials with improved properties. Investigations into its polymerization behavior, molecular assembly, and solid-state properties could lead to the design of advanced materials for various applications, such as sensors, catalysts, and electronic devices.
🧪 Related Compounds
One similar compound to N-Hydroxybenzamide is N-Hydroxyphthalimide. This compound has a similar molecular structure, with a nitrogen-hydroxy group attached to a cyclic carbon compound. N-Hydroxyphthalimide is commonly used as a radical initiator in organic synthesis reactions.
Another compound with a structure akin to N-Hydroxybenzamide is N-Hydroxyacetanilide. This compound also features a nitrogen-hydroxy group attached to a carbon compound, specifically an acetanilide moiety. N-Hydroxyacetanilide is utilized in organic chemistry as a reagent for the preparation of amides and esters.
A further analogous compound to N-Hydroxybenzamide is N-Hydroxyphthalimide-N’-butane. This compound has a nitrogen-hydroxy group attached to a phthalimide moiety linked to a butyl chain. N-Hydroxyphthalimide-N’-butane is often employed as a radical initiator in various polymerization reactions.
