2-Nitroso-1-naphthol 

2-Nitroso-1-naphthol is a chemical compound that has a variety of uses in everyday life. It is commonly used in the production of dyes, pigments, and pharmaceuticals. In the textile industry, it is utilized as a dye intermediate for coloring fabrics and garments. Additionally, 2-Nitroso-1-naphthol has been studied for its potential medicinal properties, including its role in cancer research as a potential anti-cancer agent. Overall, this compound plays a significant role in various industries and scientific research, showcasing its relevance to everyday life.

Table of Contents:

💡  Commercial Applications

2-Nitroso-1-naphthol is utilized in various commercial and industrial applications due to its unique chemical properties. It is commonly used as a dye intermediate, where it serves as a precursor in the production of synthetic dyes. Additionally, this compound has been employed in the manufacturing of photographic chemicals and pharmaceuticals, highlighting its versatility in different industries.

In terms of drug and medication applications, 2-Nitroso-1-naphthol plays a significant role in the pharmaceutical sector. It has been studied for its potential anti-tumor and anti-cancer properties, with research indicating its ability to inhibit the growth of cancer cells. Furthermore, this compound has shown promise as a therapeutic agent in the treatment of certain types of leukemia, showcasing its potential in the development of novel medications for medical use.

⚗️  Chemical & Physical Properties

2-Nitroso-1-naphthol is a solid compound that appears as yellow crystals. It has a faint odor that is not easily detectable.

The molar mass of 2-Nitroso-1-naphthol is 198.2 g/mol, and its density is 1.48 g/cm3. Compared to common food items like sugar (molar mass of 342.3 g/mol) and water (density of 1 g/cm3), 2-Nitroso-1-naphthol has a lower molar mass and higher density.

The melting point of 2-Nitroso-1-naphthol is approximately 140-142°C, and its boiling point is around 300°C. In comparison, common food items such as butter (melting point of 32-35°C) and water (boiling point of 100°C) have much lower melting and boiling points.

2-Nitroso-1-naphthol is sparingly soluble in water and has a low viscosity. This is in contrast to common food items like salt (high solubility in water) and honey (high viscosity).

🏭  Production & Procurement

2-Nitroso-1-naphthol is typically produced through the nitrosation of 1-amino-2-naphthol. This reaction involves the addition of nitrous acid to the amino group, resulting in the formation of the desired nitroso compound.

Once 2-Nitroso-1-naphthol has been synthesized, it can be procured from chemical suppliers who specialize in providing rare and specialized compounds. These suppliers often work with manufacturers to ensure timely delivery of the compound to research laboratories and industrial facilities.

The transportation of 2-Nitroso-1-naphthol is typically carried out in accordance with strict regulations governing the shipment of hazardous chemicals. The compound may be packaged in sealed containers and transported by licensed carriers to ensure its safe arrival at the intended destination.

⚠️  Safety Considerations

Safety considerations for 2-Nitroso-1-naphthol involve handling the compound with caution due to its potential hazards. It is important to wear appropriate personal protective equipment, such as gloves and safety goggles, when working with this compound to prevent skin and eye contact. Additionally, proper ventilation should be ensured to prevent inhalation of vapors, as 2-Nitroso-1-naphthol may be harmful if inhaled.

The hazard statements for 2-Nitroso-1-naphthol include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate that exposure to this compound may result in skin and eye irritation, highlighting the importance of using protective equipment such as gloves and safety goggles when handling it. It is also important to avoid breathing in vapors of 2-Nitroso-1-naphthol to prevent potential respiratory irritation.

Precautionary statements for 2-Nitroso-1-naphthol include “Wear protective gloves/eye protection” and “Avoid breathing dust/fume/gas/mist/vapors/spray.” These statements emphasize the need to take precautions to minimize exposure to this compound, such as wearing gloves and eye protection during handling. Proper ventilation should also be ensured to prevent inhalation of vapors, further reducing the risk of respiratory irritation.

🔬  Potential Research Directions

One potential research direction for 2-Nitroso-1-naphthol is its application in organic synthesis as a versatile and unique building block. This compound may serve as a precursor for the synthesis of diverse functionalized naphthalene derivatives with potential applications in drug discovery and material science.

Additionally, the investigation of the reactivity of 2-Nitroso-1-naphthol towards various nucleophiles could provide valuable insights into its chemical behavior and potential applications. Understanding the mechanisms of nucleophilic addition reactions involving this compound could lead to the development of novel synthetic methodologies for the construction of complex molecular structures.

Furthermore, the exploration of the biological activities of 2-Nitroso-1-naphthol and its derivatives could uncover new potential therapeutic agents or probes for studying biological processes. Studies investigating the interactions of this compound with biological targets could offer important clues for the development of new drugs or chemical tools for biological research.

One similar compound to 2-Nitroso-1-naphthol based upon molecular structure is 1-Nitroso-2-naphthol. This compound is structurally similar to 2-Nitroso-1-naphthol, with the nitroso group located on a different position of the naphthol ring. The presence of the nitroso group in both compounds imparts similar chemical reactivity and properties.

Another related compound is 2-Nitroso-1-naphthaldehyde. This compound shares a similar molecular structure with 2-Nitroso-1-naphthol, but with an aldehyde functional group instead of a hydroxyl group. The presence of the nitroso group in this compound results in similar chemical properties and reactivity to 2-Nitroso-1-naphthol.

A further compound with a comparable molecular structure is 2-Nitroso-1-naphthylamine. In this compound, the nitroso group is attached to an amino group on the naphthalene ring. The presence of the nitroso group in this compound imparts similar chemical reactivity and behavior to 2-Nitroso-1-naphthol, making it a related compound based on molecular structure.

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