1-Chloro-4-nitrobenzene is a chemical compound that has various industrial applications, particularly in the production of pharmaceuticals, pesticides, and dyes. While most individuals may not directly interact with this specific compound in their daily lives, it plays a crucial role in the manufacturing processes of numerous consumer products that people commonly use. Additionally, 1-Chloro-4-nitrobenzene’s presence in these industries contributes to the overall economic landscape by supporting the production of essential goods and services.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Chloro-4-nitrobenzene, also known as p-chloronitrobenzene, has several commercial and industrial applications. It is commonly used as an intermediate in the manufacturing of dyes, pharmaceuticals, and agrochemicals. Additionally, it is employed in the synthesis of pesticides and rubber chemicals. Its chemical properties make it a versatile compound for various industrial processes.
In terms of drug and medication applications, 1-Chloro-4-nitrobenzene has limited use. However, it is occasionally utilized in pharmaceutical research for the development of new drugs. Due to its chemical structure and reactivity, it can be modified to create potential drug candidates with specific therapeutic properties. Nevertheless, its primary role lies in the industrial sector rather than in the pharmaceutical industry.
Overall, the commercial and industrial applications of 1-Chloro-4-nitrobenzene make it a valuable compound in various manufacturing processes. Its versatility and chemical properties enable its use in the production of a wide range of products, from dyes and agrochemicals to pharmaceutical intermediates. Despite its limited role in drug development, its significance in industrial applications remains prominent.
⚗️ Chemical & Physical Properties
1-Chloro-4-nitrobenzene is a yellow crystalline solid with a faint odor. The compound is soluble in organic solvents such as alcohol and acetone but has limited solubility in water.
With a molar mass of 157.56 g/mol and a density of 1.49 g/cm³, 1-Chloro-4-nitrobenzene is heavier than common food items such as water (molar mass: 18.02 g/mol, density: 1.0 g/cm³) and sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm³).
The compound has a melting point of 55-57°C and a boiling point of 271°C. In comparison, common food items like butter (melting point: 32-35°C, boiling point: 100°C) and chocolate (melting point: 34-38°C, boiling point: 100°C) have lower melting and boiling points.
1-Chloro-4-nitrobenzene is sparingly soluble in water and has a low viscosity. This is in contrast to common food items like salt (soluble in water) and honey (high viscosity), which have different properties in terms of solubility and viscosity.
🏭 Production & Procurement
1-Chloro-4-nitrobenzene is typically produced through the nitration of chlorobenzene, a process which involves reacting chlorobenzene with a mixture of concentrated nitric and sulfuric acids. This reaction results in the substitution of a nitro group (-NO2) for a hydrogen atom on the benzene ring, yielding 1-Chloro-4-nitrobenzene as the final product.
The procurement of 1-Chloro-4-nitrobenzene involves purchasing the chemical from specialized chemical suppliers or manufacturers. It is important to ensure that the compound is obtained from reputable sources to guarantee its purity and quality. Once procured, 1-Chloro-4-nitrobenzene can be transported in sealed containers or drums, following all necessary safety regulations and guidelines for handling hazardous chemicals.
Transportation of 1-Chloro-4-nitrobenzene should be carried out in compliance with relevant regulations for the transportation of hazardous materials. Proper labeling, packaging, and handling procedures must be followed to prevent any leaks, spills, or accidents during transportation. It is advisable to work with experienced chemical transportation companies to ensure the safe and secure delivery of 1-Chloro-4-nitrobenzene to its intended destination.
⚠️ Safety Considerations
Safety considerations for 1-Chloro-4-nitrobenzene include the potential for skin and eye irritation upon direct contact. This compound may also be harmful if swallowed, inhaled, or absorbed through the skin. It is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat when handling 1-Chloro-4-nitrobenzene to minimize the risk of exposure. Additionally, this compound should only be used in a well-ventilated area to prevent the buildup of vapors.
Hazard statements for 1-Chloro-4-nitrobenzene include “Causes skin and eye irritation” and “May be harmful if swallowed, inhaled, or absorbed through the skin.” These statements serve as a warning to individuals who may come into contact with this compound. It is important to take these hazards seriously and follow proper safety precautions to minimize the risk of harm.
Precautionary statements for 1-Chloro-4-nitrobenzene include “Wear protective gloves/eye protection/face protection” and “Use only outdoors or in a well-ventilated area.” These statements outline specific steps that should be taken to ensure safe handling of this compound. By following these precautionary measures, individuals can reduce their risk of exposure and potential harm associated with 1-Chloro-4-nitrobenzene.
🔬 Potential Research Directions
1-Chloro-4-nitrobenzene is a compound that has garnered interest due to its potential application in various fields of research. One potential research direction is the study of its reactivity and mechanisms of its chemical transformations. Understanding how this compound interacts with other molecules can provide valuable information for the development of new synthetic methods.
Another area of research could focus on the biological activity of 1-Chloro-4-nitrobenzene. Exploring its potential as a pharmaceutical compound or investigating its toxicity profile could be valuable in the field of medicinal chemistry. Such studies could lead to the discovery of novel drug candidates or provide insights into the mechanisms of toxic effects.
Furthermore, investigations into the environmental impact of 1-Chloro-4-nitrobenzene could be a significant research direction. Assessing its persistence in the environment, potential for bioaccumulation, and overall ecological impact can contribute to the development of efficient strategies for its monitoring and remediation. Understanding how this compound interacts with environmental processes can aid in mitigating potential risks associated with its presence.
🧪 Related Compounds
One similar compound to 1-Chloro-4-nitrobenzene is 2-Chloro-4-nitrobenzene, which shares a common chloro substituent but differs in the position of the nitro group. This compound exhibits similar chemical reactivity to 1-Chloro-4-nitrobenzene due to the chlorine atom and nitro group, allowing for comparative analysis of their properties.
Another related compound is 1-Chloro-2-nitrobenzene, which possesses a similar molecular structure to 1-Chloro-4-nitrobenzene but differs in the position of the nitro group. This compound provides a useful comparison for studying the effects of nitro group positioning on chemical reactivity and physical properties.
Additionally, 1,4-Dichloro-2-nitrobenzene is structurally analogous to 1-Chloro-4-nitrobenzene, with the presence of two chlorine atoms and a nitro group. This compound offers insight into the impact of additional chloro substituents on the reactivity and behavior of nitrobenzene derivatives.
