4-Methylbenzoic acid, also known as p-toluylic acid, is a compound that is commonly used in the production of pharmaceuticals, dyes, and fragrances. It plays a significant role in everyday life as it is used in the synthesis of various medications, in the manufacturing of colorants for textiles and plastics, and in the creation of scents for perfumes and personal care products. Its versatility and widespread application make 4-Methylbenzoic acid a key component in numerous industries that impact our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Methylbenzoic acid, also known as p-Toluic acid, has several commercial and industrial applications. It is commonly used as an intermediate in the production of dyes, perfumes, and pharmaceuticals. Additionally, 4-Methylbenzoic acid is used in the synthesis of polymers and in the manufacturing of plasticizers.
In the realm of drug and medication applications, 4-Methylbenzoic acid plays a key role in the production of various pharmaceuticals. It is used as a precursor in the synthesis of certain drugs, such as ibuprofen, an anti-inflammatory medication. 4-Methylbenzoic acid is also utilized in the pharmaceutical industry to produce active pharmaceutical ingredients for a wide range of medications.
In conclusion, 4-Methylbenzoic acid has significant commercial and industrial applications, particularly in the production of dyes, perfumes, pharmaceuticals, and polymers. Additionally, it is an important precursor in the synthesis of various drugs and medications, showcasing its versatility and importance in different sectors.
⚗️ Chemical & Physical Properties
4-Methylbenzoic acid is a white solid with a faint odor. It is often described as having a slightly aromatic smell.
The molar mass of 4-Methylbenzoic acid is approximately 136.15 g/mol, with a density of 1.09 g/cm3. In comparison, common food items such as sugar have a molar mass of 342.30 g/mol and a density of 1.59 g/cm3.
The melting point of 4-Methylbenzoic acid is around 105-107°C, while the boiling point is approximately 275-280°C. In contrast, common food items like butter have a melting point of 32-35°C and a boiling point of 177°C.
4-Methylbenzoic acid is sparingly soluble in water, but has a high viscosity. This differs from common food items like salt, which is highly soluble in water and has a low viscosity.
🏭 Production & Procurement
4-Methylbenzoic acid, also known as p-toluic acid, is typically produced through the oxidation of p-xylene or toluene. This oxidation process involves the use of strong oxidizing agents such as chromic acid or potassium permanganate to convert the precursor aromatic compounds into the desired product.
Once 4-Methylbenzoic acid is produced, it can be procured from chemical suppliers or manufacturers specializing in aromatic carboxylic acids. The compound is commonly available in both liquid and solid forms, depending on the specific requirements of the end user. Procurement of 4-Methylbenzoic acid can be facilitated through established supply chains and distribution networks within the chemical industry.
Transportation of 4-Methylbenzoic acid is typically carried out using specialized containers designed for the safe handling of corrosive or hazardous substances. Due to its classification as a hazardous material, the compound must be transported in compliance with applicable regulations and guidelines to ensure the safety of both the product and the individuals involved in its transportation. Proper labeling and documentation are essential for the legal and safe transport of 4-Methylbenzoic acid.
⚠️ Safety Considerations
Safety considerations for 4-Methylbenzoic acid include potential skin and eye irritation upon contact. Inhaling the vapors or mist of this compound may cause respiratory irritation. It is essential to handle 4-Methylbenzoic acid in a well-ventilated area and wear appropriate personal protective equipment, such as gloves and goggles, to prevent any potential exposure.
Hazard statements for 4-Methylbenzoic acid include “Causes skin irritation” and “Causes serious eye irritation.” Additionally, this compound may cause respiratory irritation if inhaled. It is important to take precautionary measures to minimize the risk of exposure to 4-Methylbenzoic acid, such as using appropriate protective equipment and working in a well-ventilated area.
Precautionary statements for 4-Methylbenzoic acid include avoiding skin contact and eye contact, as well as inhalation of vapors or mist. It is recommended to handle this compound in a fume hood or well-ventilated area to minimize inhalation exposure. In case of skin or eye contact, thoroughly rinse affected areas with water and seek medical attention if irritation persists.
🔬 Potential Research Directions
One potential research direction for 4-Methylbenzoic acid is the study of its pharmaceutical properties and potential applications in drug development. Research could focus on understanding its therapeutic potential, mechanisms of action, and pharmacokinetics.
Another area of interest lies in investigating the environmental fate and toxicity of 4-Methylbenzoic acid. This research could explore its behavior in various environmental matrices, its potential for bioaccumulation, and its impact on ecosystems. Such studies are crucial for assessing the environmental risks associated with the compound.
Furthermore, researchers could explore the synthesis and modification of 4-Methylbenzoic acid derivatives for various industrial applications. The development of new derivatives with enhanced properties, such as increased solubility, stability, or reactivity, could have significant implications for industries ranging from materials science to agriculture.
Lastly, studies could be carried out to elucidate the role of 4-Methylbenzoic acid in biological systems, particularly its interactions with enzymes, proteins, and other biomolecules. Understanding its biological activities and potential as a molecular probe could open up new avenues for research in biochemistry and molecular biology.
🧪 Related Compounds
One similar compound to 4-Methylbenzoic acid is 3-Methylbenzoic acid, which has a molecular structure that differs by the position of the methyl group on the benzene ring. Despite this difference in positioning, both compounds share similar chemical properties due to their aromatic nature and carboxylic acid functional group.
Another similar compound is 4-Ethylbenzoic acid, which shares the same molecular formula as 4-Methylbenzoic acid but differs by the substitution of a methyl group with an ethyl group. This slight modification in structure results in changes in the compound’s physical and chemical properties, yet it retains the core characteristics of a benzoic acid derivative.
Additionally, 4-Isopropylbenzoic acid is a similar compound to 4-Methylbenzoic acid wherein the methyl group is replaced by an isopropyl group. Despite this alteration in structure, both compounds exhibit similar reactivity and behavior due to the shared benzoic acid moiety. The positioning of the substituent groups on the benzene ring plays a vital role in determining the compound’s properties and behavior in chemical reactions.
