1,2-Dichloro-4-nitrobenzene is a chemical compound that has various industrial applications, including as a precursor in the production of pesticides and pharmaceuticals. While not directly relevant to everyday life for the average individual, the compound plays a crucial role in supporting industries that contribute to the development of products and technologies that improve our quality of life. From agricultural practices to healthcare advancements, 1,2-Dichloro-4-nitrobenzene is a key ingredient in the production of numerous goods that impact society on a larger scale.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,2-Dichloro-4-nitrobenzene, a compound also known as nitrochlorobenzene, finds various commercial and industrial applications. It is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. Additionally, it is utilized in the manufacture of rubber chemicals, pesticides, and organic solvents.
In the realm of drug and medication applications, 1,2-Dichloro-4-nitrobenzene has limited use. However, certain derivatives of this compound have been explored for their potential as antitumor agents. Specifically, research has focused on their ability to inhibit tumor cell growth and proliferation, making them a subject of interest in cancer treatment studies. Despite these potential medicinal applications, further research is needed to fully understand the mechanisms of action and effectiveness of these derivatives.
⚗️ Chemical & Physical Properties
1,2-Dichloro-4-nitrobenzene is a yellow crystalline solid with a faint odor. The compound is insoluble in water but soluble in organic solvents due to its nonpolar nature.
With a molar mass of 202.48 g/mol and a density of 1.52 g/cm^3, 1,2-Dichloro-4-nitrobenzene is heavier and denser than common food items such as sugar and salt.
1,2-Dichloro-4-nitrobenzene has a melting point of 41-42°C and a boiling point of 295-296°C. These values are significantly higher than those of common food items like butter and chocolate.
The compound has low solubility in water and exhibits high viscosity. Compared to common food items like vinegar and honey, 1,2-Dichloro-4-nitrobenzene is much less soluble in water and more viscous.
🏭 Production & Procurement
1,2-Dichloro-4-nitrobenzene is primarily produced through the nitration of 1,2-dichlorobenzene using a mixture of concentrated nitric and sulfuric acids. The reaction is carried out at elevated temperatures to facilitate the substitution of the nitro group onto the benzene ring.
Once 1,2-Dichloro-4-nitrobenzene is synthesized, it can be procured from chemical suppliers who specialize in the production and distribution of specialty chemicals. The compound is typically transported in sealed containers to prevent exposure to moisture or other contaminants that could degrade its quality.
Due to its hazardous nature, proper handling and storage protocols must be followed when procuring 1,2-Dichloro-4-nitrobenzene. It is recommended that individuals or organizations seeking to obtain this compound work with licensed chemical suppliers who can provide guidance on safe transportation and storage practices.
⚠️ Safety Considerations
Safety considerations for 1,2-Dichloro-4-nitrobenzene must be taken seriously due to its potential health hazards. This chemical is classified as harmful if swallowed, causing irritation to the gastrointestinal tract. Furthermore, it can cause skin and eye irritation upon contact. It is important to handle this compound with proper protective equipment, such as gloves and goggles, in a well-ventilated area to minimize exposure.
Hazard statements for 1,2-Dichloro-4-nitrobenzene include “Harmful if swallowed,” “Causes skin irritation,” and “Causes serious eye irritation.” These statements highlight the potential risks associated with this chemical and emphasize the importance of taking necessary precautions when handling it. It is crucial to adhere to proper safety protocols to prevent any adverse effects on health.
Precautionary statements for 1,2-Dichloro-4-nitrobenzene recommend avoiding ingestion, inhalation, and contact with skin and eyes. It is advised to wear protective gloves, clothing, and eye protection when working with this chemical to minimize the risk of exposure. In case of contact, it is important to rinse affected areas immediately with plenty of water and seek medical attention if necessary. Additionally, proper ventilation should be ensured when using this compound to prevent inhalation of fumes.
🔬 Potential Research Directions
Potential research directions for 1,2-Dichloro-4-nitrobenzene may include further investigation into its environmental impact and remediation strategies.
Studies could focus on the synthesis of novel derivatives of 1,2-Dichloro-4-nitrobenzene and their potential applications in pharmacology or material science.
Exploring the mechanism of action of 1,2-Dichloro-4-nitrobenzene on biological systems could provide valuable insights into its toxicological properties and help in developing targeted therapies.
🧪 Related Compounds
One similar compound to 1,2-Dichloro-4-nitrobenzene is 1,2-Dinitro-4-chlorobenzene. This compound shares a similar structure, with substituents at the 1 and 4 positions of the benzene ring. In this case, the nitro group is located at the ortho position to the chloro group, creating a different set of chemical properties.
Another compound with a comparable structure is 1,4-Dichloro-2-nitrobenzene. In this compound, the positions of the chloro and nitro groups are reversed compared to 1,2-Dichloro-4-nitrobenzene. This arrangement results in a different spatial orientation of the groups, potentially leading to distinct chemical reactivity.
A third similar compound is 2,4-Dichloro-1-nitrobenzene. In this case, the nitro group is located at the para position to the chloro groups, creating a different electronic distribution within the molecule. This compound may exhibit different physical and chemical properties compared to 1,2-Dichloro-4-nitrobenzene due to the altered position of the substituents on the benzene ring.
