4-tert-Butylcatechol, a chemical compound commonly known as TBC, plays a crucial role in everyday life as a stabilizer for various substances, including polymers, oils, and fats. It is widely used in industries such as food processing, pharmaceuticals, and cosmetics to prevent oxidation and extend the shelf life of products. In essence, 4-tert-Butylcatechol helps to preserve the quality and safety of many consumer goods and industrial materials, making it an important component of modern life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-tert-Butylcatechol, also known as TBC, has several commercial and industrial applications. It is commonly used as a stabilizer in the production of polymers, including synthetic rubber and resins. TBC is particularly effective in inhibiting the formation of free radicals, thus prolonging the shelf life and durability of these materials.
In addition to its role in polymer production, 4-tert-Butylcatechol is also utilized as an antioxidant in various industries, such as the manufacturing of paints, coatings, and adhesives. Its ability to prevent oxidative degradation makes it a valuable additive in preserving the quality of these products. TBC is also employed in the production of fuel additives and lubricants to enhance their stability and performance.
Despite its primarily industrial applications, 4-tert-Butylcatechol has shown potential in the field of medicine and pharmacology. Research has suggested that TBC may possess anti-inflammatory and anti-cancer properties, leading to investigations into its potential use in pharmaceutical formulations. While further studies are needed to fully explore its medicinal benefits, the versatility of 4-tert-Butylcatechol makes it a promising candidate for future drug and medication applications.
⚗️ Chemical & Physical Properties
4-tert-Butylcatechol is a white crystalline solid with a faint phenolic odor. It is commonly used as a stabilizer in certain polymers due to its antioxidant properties.
The molar mass of 4-tert-Butylcatechol is 166.21 g/mol and its density is approximately 1.09 g/cm^3. Compared to common food items like sugar (molar mass of 342.3 g/mol) and water (density of 1 g/cm^3), 4-tert-Butylcatechol has a lower molar mass and higher density.
The melting point of 4-tert-Butylcatechol is around 116-117°C, while its boiling point is approximately 262-265°C. In comparison, common food items like butter (melting point of 32°C) and water (boiling point of 100°C) have significantly lower melting and boiling points.
4-tert-Butylcatechol is sparingly soluble in water, with a solubility of approximately 2.1 g/L at room temperature. It has a relatively low viscosity compared to common food items like honey, which has a much higher viscosity.
🏭 Production & Procurement
In the realm of organic chemistry, 4-tert-Butylcatechol is typically produced through the alkylation of catechol with tert-butyl alcohol. This reaction is often catalyzed by an acid, such as sulfuric acid or hydrochloric acid. Following the reaction, purification methods such as recrystallization or distillation are commonly employed to isolate the desired product.
4-tert-Butylcatechol can be procured through various chemical suppliers specializing in fine chemicals or organic intermediates. Once obtained, the compound can be transported in sealed, labeled containers to ensure safe handling. Depending on the quantity needed, different shipping methods and regulations may apply, necessitating compliance with local and international guidelines for hazardous materials.
Due to the compound’s stability and non-hazardous nature, 4-tert-Butylcatechol is relatively straightforward to transport compared to more reactive or volatile chemicals. It is important to store the compound in a cool, dry place away from direct sunlight and incompatible materials to prevent degradation. When moving bulk quantities, proper labeling and documentation must be provided to comply with legal requirements and ensure safe handling throughout the supply chain.
⚠️ Safety Considerations
Safety considerations for 4-tert-Butylcatechol should not be taken lightly as it is classified as a hazardous substance. This compound can cause skin and eye irritation upon contact. It is also harmful if swallowed, inhaled, or absorbed through the skin. Therefore, it is important to handle 4-tert-Butylcatechol with caution, wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat.
Hazard statements for 4-tert-Butylcatechol include “Causes skin and eye irritation,” “Harmful if swallowed,” “Harmful if inhaled,” and “Harmful if absorbed through the skin.” These statements indicate the various ways in which exposure to this compound can be detrimental to human health. It is important to take these hazards into consideration when working with 4-tert-Butylcatechol to prevent any harm.
Precautionary statements for 4-tert-Butylcatechol include “Wear protective gloves/protective clothing/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” “IF IN EYES: Rinse cautiously with water for several minutes,” and “IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.” These statements provide guidance on how to safely handle and respond in case of exposure to 4-tert-Butylcatechol. It is crucial to follow these precautions to minimize the risk of harm to oneself or others.
🔬 Potential Research Directions
Research on 4-tert-Butylcatechol may explore its potential as an antioxidant in various industries, particularly in the polymerization of butadiene and related compounds. Studies could investigate its effectiveness in inhibiting undesired oxidation reactions during polymer production, leading to improvements in product quality and process efficiency.
Further investigation into the environmental impact of 4-tert-Butylcatechol is warranted, as its widespread use in industry may have implications for ecosystem health. Research could focus on understanding its fate in the environment, including its degradation pathways and potential accumulation in organisms. This knowledge could inform regulatory strategies to minimize its ecological footprint.
The synthesis and chemical properties of 4-tert-Butylcatechol may be of interest for organic chemists studying aromatic compounds. Future research could involve exploring novel synthetic methodologies for its preparation, as well as elucidating the mechanisms of its antioxidant activity. These investigations could contribute to a deeper understanding of structure-activity relationships in catechol derivatives.
Studies on the biological effects of 4-tert-Butylcatechol could shed light on its potential as a therapeutic agent in medicine. Research may investigate its antioxidant properties in mitigating oxidative stress-related diseases, such as neurodegenerative disorders. Understanding its bioavailability, metabolism, and pharmacokinetics could pave the way for future drug development efforts.
🧪 Related Compounds
One similar compound to 4-tert-Butylcatechol based on molecular structure is 3-tert-Butylcatechol. In this compound, a tert-butyl group is attached at the 3-position of the catechol ring instead of the 4-position. This results in similar steric hindrance and hydrophobic properties as 4-tert-Butylcatechol.
Another related compound is 2-tert-Butylcatechol, where the tert-butyl group is attached at the 2-position of the catechol ring. This compound shares similar structural features and chemical reactivity with both 4-tert-Butylcatechol and 3-tert-Butylcatechol. The placement of the tert-butyl group on the catechol ring influences the compound’s physical and chemical properties.
One more compound similar to 4-tert-Butylcatechol is 3-tert-Amylcatechol. In this compound, a larger amyl group is attached at the 3-position of the catechol ring instead of the tert-butyl group. This modification results in different steric effects and hydrophobic interactions compared to 4-tert-Butylcatechol, while still maintaining the catechol core structure. The presence of the amyl group influences the compound’s solubility and biological activity.
