2-(Diisopropylamino)ethanol, a compound commonly used as a solvent in various industrial processes and as a catalyst in organic synthesis, holds relevance to everyday life due to its use in the manufacturing of pharmaceuticals, personal care products, and pesticides. Its applications extend beyond the lab environment, making it an essential component in products that are integral to modern living.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-(Diisopropylamino)ethanol, also known as DIPEA, finds various commercial and industrial applications. It is commonly used as a catalyst in chemical reactions, particularly in the production of pharmaceuticals and agricultural chemicals. This compound is also utilized as a solvent in the manufacturing of dyes, resins, and coatings.
In the realm of drug and medication applications, 2-(Diisopropylamino)ethanol plays a significant role. It is commonly employed as a reactant in the synthesis of pharmaceutical drugs, particularly those with biological activity. Due to its properties as a base, DIPEA is also utilized in the creation of various drug formulations to help achieve the desired pH levels for stability and efficacy.
Overall, 2-(Diisopropylamino)ethanol is a versatile compound with widespread uses in both commercial and industrial settings. Its unique properties make it a valuable component in the production of chemicals, pharmaceuticals, and other products essential to various industries. In the field of drug development, DIPEA’s role as a catalyst and pH modifier makes it a crucial ingredient in the creation of pharmaceutical formulations.
⚗️ Chemical & Physical Properties
2-(Diisopropylamino)ethanol is a colorless liquid with a distinct amine odor. The odor can be described as faintly sweet and reminiscent of ammonia, but less pungent.
The molar mass of 2-(Diisopropylamino)ethanol is 131.24 g/mol, and its density is approximately 0.89 g/cm^3. In comparison to common food items, this compound has a higher molar mass and lower density than water, but similar to many oils and fats.
The melting point of 2-(Diisopropylamino)ethanol is -40°C, and its boiling point is 131-133°C. These values are significantly lower than those of common food items like sugar, salt, and water, which have much higher melting and boiling points.
2-(Diisopropylamino)ethanol is highly soluble in water and possesses a low viscosity. This solubility is comparable to sugar and salt, but its viscosity is much lower than that of honey or syrup.
🏭 Production & Procurement
2-(Diisopropylamino)ethanol, commonly known as DIPEA, is produced through a reaction between 2-chloroethyl diisopropylamine hydrochloride and an alcohol. This reaction typically takes place under basic conditions and yields 2-(Diisopropylamino)ethanol as the final product.
In terms of procurement and transportation, 2-(Diisopropylamino)ethanol is commonly available for purchase from chemical suppliers. It is typically stored in sealed containers to prevent exposure to moisture and air, as it is a hygroscopic compound. When transporting 2-(Diisopropylamino)ethanol, it is important to follow all regulations regarding the transportation of hazardous chemicals.
Given its widespread use in various industries, 2-(Diisopropylamino)ethanol is often procured in bulk quantities for manufacturing processes. Suppliers may offer various packaging options based on the requirements of the purchaser, ensuring safe and efficient delivery of the compound. Proper handling and storage procedures should be followed to maintain the integrity and quality of 2-(Diisopropylamino)ethanol during procurement and transportation.
⚠️ Safety Considerations
Safety considerations for 2-(Diisopropylamino)ethanol include the importance of storing the chemical in a well-ventilated area away from sources of ignition, heat, and incompatible materials. This compound should be handled with care, wearing appropriate protective clothing such as gloves, goggles, and a lab coat. In case of accidental exposure, it is recommended to seek medical advice immediately and have the Safety Data Sheet readily available for reference.
Hazard statements for 2-(Diisopropylamino)ethanol include its classification as a flammable liquid and skin irritant. This compound may cause skin and eye irritation upon contact, as well as respiratory irritation if inhaled. Additionally, 2-(Diisopropylamino)ethanol has the potential to result in serious health effects if swallowed or absorbed through the skin, highlighting the importance of proper handling and storage procedures.
Precautionary statements for 2-(Diisopropylamino)ethanol stress the necessity of storing the chemical in a cool, well-ventilated place away from heat sources and incompatible materials. It is essential to keep this compound tightly sealed in its original container and away from oxidizing agents to prevent potential hazards. Personal protective equipment such as gloves, goggles, and a lab coat should be worn when handling 2-(Diisopropylamino)ethanol to minimize the risk of skin and eye irritation. Additionally, it is crucial to thoroughly wash hands and exposed skin after handling this compound and seek medical attention in case of accidental exposure or ingestion.
🔬 Potential Research Directions
One potential research direction for 2-(Diisopropylamino)ethanol involves studying its use as a chemical intermediate in the synthesis of pharmaceutical compounds. Its unique structure and properties make it a promising building block for the creation of new drug molecules with enhanced biological activity.
Another area of research interest could involve investigating the potential applications of 2-(Diisopropylamino)ethanol as a solvent or additive in chemical processes. Understanding its solubility and reactivity characteristics could lead to the development of more efficient and environmentally friendly industrial processes.
Furthermore, exploring the toxicological profile of 2-(Diisopropylamino)ethanol is essential for assessing its safety for human and environmental health. Studies evaluating its potential harmful effects and establishing proper handling procedures are crucial to ensuring its responsible use in various applications.
🧪 Related Compounds
One similar compound to 2-(Diisopropylamino)ethanol based on molecular structure is 2-(Dibutylamino)ethanol. In this compound, the amino group is attached to the ethyl group, just as in 2-(Diisopropylamino)ethanol. However, in this case, the substituent groups on the nitrogen atom are butyl groups instead of isopropyl groups.
Another analogous compound is 2-(Diethylamino)ethanol. In this compound, the amino group is also attached to the ethyl group, similar to 2-(Diisopropylamino)ethanol. However, the substituent groups on the nitrogen atom are ethyl groups rather than isopropyl groups. This structural similarity makes 2-(Diethylamino)ethanol a comparable compound to 2-(Diisopropylamino)ethanol.
A further compound with a similar structure is 2-(Dipropylamino)ethanol. In this compound, the amino group is attached to the ethyl group just like in 2-(Diisopropylamino)ethanol. However, the two substituent groups on the nitrogen atom are propyl groups instead of isopropyl groups. This similarity in molecular structure makes 2-(Dipropylamino)ethanol another compound akin to 2-(Diisopropylamino)ethanol.