1,10-Phenanthroline

1,10-Phenanthroline, a heterocyclic organic compound, holds significant importance in everyday life due to its diverse applications in various fields. It is commonly utilized in analytical chemistry as a chelating agent for metal ions, aiding in the determination and quantification of various metals in biological and environmental samples.

Furthermore, 1,10-Phenanthroline plays a pivotal role in the field of pharmacology, serving as a precursor in the synthesis of pharmaceuticals and therapeutic drugs. Its ability to form stable complexes with metal ions also makes it valuable in bioinorganic chemistry for studying metal-based biological processes.

Moreover, 1,10-Phenanthroline finds use in industries such as textiles, where it acts as a dyeing agent, and in the field of material science for its role in the synthesis of metal-organic frameworks. Overall, the versatile properties of 1,10-Phenanthroline contribute to its relevance in various aspects of everyday life.

Table of Contents:

💡 Commercial Applications

1,10-Phenanthroline, a nitrogen-containing heterocyclic compound, has various commercial and industrial applications. It is commonly used as a chelating agent in the metal industry for its ability to form stable complexes with metal ions. These complexes can be utilized in analytical chemistry, catalysis, and electrochemistry.

In the pharmaceutical field, 1,10-Phenanthroline has been investigated for its potential drug and medication applications. Studies have shown that it exhibits antiviral, antibacterial, and anticancer properties, making it a promising candidate for drug development. Its ability to chelate metal ions may also play a role in enhancing the efficacy of certain medications.

Research on 1,10-Phenanthroline continues to uncover new potential applications in both commercial and medicinal fields. Its versatile properties as a chelating agent and its promising biological activities make it a valuable molecule for various industries and scientific advancements.

⚗️ Chemical & Physical Properties

1,10-Phenanthroline appears as a solid with a white to light yellow color and is odorless. It is commonly used as a reagent in chemical reactions due to its chelating properties.

With a molar mass of 180.20 g/mol and a density of 1.070 g/cm^3, 1,10-Phenanthroline falls within the range of common organic compounds in terms of molar mass and density. It is lighter than many household items such as water (molar mass: 18.015 g/mol, density: 1.00 g/cm^3) but heavier than air (molar mass: 28.97 g/mol, density: 0.0012 g/cm^3).

1,10-Phenanthroline has a melting point of 131-133°C and a boiling point of 372°C. These values are higher than those of many common household items such as sugar (melting point: 186°C, boiling point: 186°C) and water (melting point: 0°C, boiling point: 100°C).

1,10-Phenanthroline is sparingly soluble in water and has a low viscosity. This is in contrast to many common household items such as salt (highly soluble in water) and honey (high viscosity), highlighting its unique characteristics as a chemical compound.

🏭 Production & Procurement

1,10-Phenanthroline is typically produced through the reaction of o-phenylenediamine with glyoxal in the presence of hydrochloric acid or sulfuric acid. This reaction results in the formation of a complex mixture of products, which can be separated and purified to obtain 1,10-Phenanthroline in its pure form.

1,10-Phenanthroline can be procured from chemical suppliers that specialize in providing specialty chemicals for research and industrial applications. It is typically supplied in solid form, either as a powder or crystalline substance. The compound is relatively stable under ambient conditions but should be handled with care due to its potential toxicity.

When procuring 1,10-Phenanthroline, it is important to ensure that proper handling and storage procedures are followed to prevent contamination or degradation of the compound. The chemical should be transported in sealed containers to prevent exposure to moisture or air, which can degrade its quality. Additionally, appropriate safety precautions should be taken during transportation to minimize the risk of accidents or spills.

⚠️ Safety Considerations

Safety considerations for 1,10-Phenanthroline include taking precautions to avoid skin contact, as it may cause irritation or sensitization. It is important to work with this compound in a well-ventilated area to prevent inhalation of fumes, which can cause respiratory irritation. Additionally, proper personal protective equipment, such as gloves and safety glasses, should be worn when handling 1,10-Phenanthroline to minimize risks of exposure.

1,10-Phenanthroline is a chelating agent that is commonly used in chemical analysis and in the coordination chemistry of transition metals. It forms stable complexes with various metal ions, making it useful in various applications such as spectrophotometric analysis and metal extraction processes. Its ability to form stable complexes with metals is attributed to its bidentate ligand properties, allowing it to coordinate with metal ions through two nitrogen atoms in its molecular structure.

Hazard statements for 1,10-Phenanthroline include being harmful if swallowed or inhaled, causing skin and eye irritation, and potentially causing allergic skin reactions. It may also be harmful to aquatic life with long-lasting effects if released into the environment. It is important to handle this compound with caution and dispose of it properly according to local regulations to prevent environmental contamination and harm.

Precautionary statements for 1,10-Phenanthroline include wearing protective gloves, clothing, and eye protection when handling the compound to minimize risks of skin and eye irritation. It is important to work with 1,10-Phenanthroline in a well-ventilated area or under a fume hood to prevent inhalation of fumes. In case of skin contact, the affected area should be washed thoroughly with soap and water, and in case of ingestion or inhalation, medical attention should be sought immediately.

🔬 Potential Research Directions

Further research on 1,10-Phenanthroline may explore its potential applications in coordination chemistry, particularly its ability to form stable complexes with various metal ions.

The development of novel derivatives of 1,10-Phenanthroline with modified structures could be a promising area for future investigation to enhance its selectivity and affinity for certain metal ions.

Investigations into the biological activities of 1,10-Phenanthroline and its analogs may shed light on their potential as therapeutic agents, such as in anticancer or antimicrobial treatments.

One similar compound to 1,10-Phenanthroline is 2,2′-Bipyridine. This compound consists of two pyridine rings connected by a carbon-carbon bond. 2,2′-Bipyridine is commonly used in coordination chemistry due to its ability to chelate metal ions with its nitrogen atoms.

Another compound similar to 1,10-Phenanthroline is 2,2′-Dipyridylamine. This compound is structurally related to 1,10-Phenanthroline but contains an amine functional group. 2,2′-Dipyridylamine is used in the synthesis of coordination polymers and metal-organic frameworks due to its ability to coordinate with metal ions.

Piperazine is yet another compound similar to 1,10-Phenanthroline. It is a heterocyclic organic compound containing two nitrogen atoms in a six-membered ring. Piperazine is known for its use as a building block in pharmaceutical compounds and as a complexing agent in metal extraction processes.

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