2-Amino-1-phenylethanol is a compound that holds relevance in everyday life due to its role as a precursor in the production of various pharmaceuticals and fragrances. This compound is commonly used in the synthesis of medications for conditions such as hypertension and depression, as well as in the creation of perfumes and personal care products. Its versatile applications in these industries make it an important component in our daily lives, contributing to the development of essential products that we rely on for health and well-being.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Amino-1-phenylethanol, also known as beta-phenylethylamine, finds various commercial and industrial applications due to its unique properties. It is commonly used as a fragrance ingredient in perfumes and colognes, providing a floral and sweet scent. Additionally, it is utilized in the production of pharmaceuticals and other chemical compounds.
In the realm of drug and medication applications, 2-Amino-1-phenylethanol has shown potential as a central nervous system stimulant. With its ability to cross the blood-brain barrier, it is being studied for its potential therapeutic effects on conditions such as depression and attention deficit hyperactivity disorder (ADHD). Research is ongoing to explore the full range of its pharmacological properties.
Due to its unique chemical structure and properties, 2-Amino-1-phenylethanol has garnered interest in various industries beyond fragrance and pharmaceuticals. Its potential as a precursor in the synthesis of novel compounds for industrial applications, such as agrochemicals and polymers, is an area of active exploration. As research continues to uncover new possibilities for this compound, its versatility in both commercial and industrial settings is likely to expand.
⚗️ Chemical & Physical Properties
2-Amino-1-phenylethanol is a colorless to pale yellow liquid with a faint sweet odor.
The molar mass of 2-Amino-1-phenylethanol is approximately 135.19 g/mol, and its density is about 1.034 g/cm³. This places it in the range of common household items in terms of molar mass and density, such as ethanol and vinegar.
The melting point of 2-Amino-1-phenylethanol is around 70-73°C, while the boiling point is approximately 288-290°C. These values are relatively high compared to common household items like water and cooking oil.
2-Amino-1-phenylethanol is slightly soluble in water, but has a higher viscosity than water. This makes it less soluble and more viscous than common household items like salt and sugar.
🏭 Production & Procurement
2-Amino-1-phenylethanol, a compound also known as α-methylbenzylamine or β-phenyl-1-aminoethanol, is commonly produced through the reduction of the corresponding nitro compound. The reduction can be achieved through various methods, such as catalytic hydrogenation or using reducing agents like iron or zinc in acidic conditions. The resulting 2-Amino-1-phenylethanol is typically isolated and purified through distillation or crystallization processes.
Procuring 2-Amino-1-phenylethanol commercially can be done through chemical suppliers or manufacturers specializing in fine chemicals. The compound is often available in various purities and quantities, with purity levels reaching up to 99% or higher. Transportation of 2-Amino-1-phenylethanol typically involves following strict regulations for handling hazardous chemicals, including proper labeling, packaging, and compliance with transportation guidelines for hazardous materials.
Upon procurement, 2-Amino-1-phenylethanol can be stored in a cool, dry place away from sources of ignition or heat. The compound should also be kept in a well-ventilated area and away from incompatible materials, such as strong oxidizing agents. Proper safety precautions, including the use of personal protective equipment like gloves and goggles, should be observed when handling 2-Amino-1-phenylethanol to prevent exposure and accidents.
⚠️ Safety Considerations
Safety considerations for 2-Amino-1-phenylethanol should include proper handling and storage to prevent any accidents or exposure. This compound should be stored in a cool, dry place away from heat and sources of ignition. It is important to wear appropriate personal protective equipment when handling 2-Amino-1-phenylethanol, such as gloves, goggles, and a lab coat, to prevent skin contact and inhalation of fumes.
In terms of its pharmacology, 2-Amino-1-phenylethanol acts as a precursor for the synthesis of various pharmaceutical compounds. It has been used in the production of drugs such as antihistamines and antitussives. This compound may also have potential applications in the development of novel therapeutic agents due to its ability to interact with certain receptors in the body.
Hazard statements for 2-Amino-1-phenylethanol should include information about its potential hazards to health and the environment. This compound may cause skin and eye irritation upon contact, and prolonged or repeated exposure may lead to adverse effects. In addition, 2-Amino-1-phenylethanol may be harmful if swallowed or inhaled, and precautions should be taken to prevent accidental ingestion or inhalation.
Precautionary statements for 2-Amino-1-phenylethanol should emphasize the importance of handling this compound with care to minimize risks. It is advised to work with 2-Amino-1-phenylethanol in a well-ventilated area to prevent exposure to vapors. In case of skin or eye contact, the affected area should be rinsed thoroughly with water and medical attention sought if necessary. Proper disposal methods should be followed to prevent environmental contamination.
🔬 Potential Research Directions
Research on 2-Amino-1-phenylethanol, a chiral compound, has shown promise in the field of asymmetric synthesis and catalysis due to its versatile reactivity and potential for enantioselective transformations.
Further studies could explore the development of novel synthetic methodologies utilizing 2-Amino-1-phenylethanol as a key building block in the preparation of biologically active compounds or pharmaceutical intermediates.
Additionally, investigations into the biological activity and pharmacological potential of 2-Amino-1-phenylethanol and its derivatives may yield valuable insights into their therapeutic applications, such as in the treatment of neurological disorders or cancer.
🧪 Related Compounds
One similar compound to 2-Amino-1-phenylethanol based on molecular structure is 2-Amino-1-propanol. This compound has a similar structure to 2-Amino-1-phenylethanol, but with a three-carbon chain instead of a two-carbon chain. The presence of an amino group and a hydroxyl group in the molecule gives it similar chemical properties to 2-Amino-1-phenylethanol.
Another similar compound is 2-Amino-1-butanol, which also shares a similar molecular structure with 2-Amino-1-phenylethanol. In this compound, the carbon chain is extended to four carbons with an amino group and a hydroxyl group attached. Like 2-Amino-1-phenylethanol, 2-Amino-1-butanol has potential applications in organic synthesis and pharmaceutical research.
3-Amino-1-phenylpropan-1-ol is another compound that bears resemblance to 2-Amino-1-phenylethanol in terms of molecular structure. This compound has a three-carbon chain with an amino group and a hydroxyl group attached to the central carbon, similar to the structure of 2-Amino-1-phenylethanol. The presence of the phenyl group in this compound adds a level of complexity to its chemical properties, making it a potentially interesting molecule for various applications.
