4-Nitrophenylacetic acid is a chemical compound that is used in various industries, including pharmaceuticals, cosmetics, and agriculture. Its relevance to everyday life lies in its role as a building block for the synthesis of important drugs, fragrances, and herbicides. Additionally, this compound is commonly employed in research laboratories for its versatile chemical properties, making it a valuable tool in the development of new materials and technologies. While not directly encountered by most individuals in their daily routines, the widespread applications of 4-Nitrophenylacetic acid highlight its significance in advancing various aspects of modern society.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Nitrophenylacetic acid, also known as p-nitrophenylacetic acid, is commonly used in commercial and industrial applications as a precursor for the synthesis of pharmaceuticals and agrochemicals. It is a key intermediate in the production of nitroacetic acid, which is further utilized in the synthesis of various chemicals and compounds.
In addition to its role in the commercial and industrial sectors, 4-Nitrophenylacetic acid also finds applications in the field of drug and medication development. It is used as a building block in the synthesis of active pharmaceutical ingredients for a wide range of therapeutic areas. The compound’s versatile chemical structure makes it a valuable component in the creation of new drug formulations and medications.
Due to its importance as a versatile intermediate compound, 4-Nitrophenylacetic acid plays a crucial role in various industries and research fields. Its unique chemical properties and ability to undergo diverse chemical reactions make it a valuable tool for pharmaceutical, agricultural, and other scientific applications. In summary, 4-Nitrophenylacetic acid holds significant commercial, industrial, and pharmaceutical relevance in the modern chemical landscape.
⚗️ Chemical & Physical Properties
4-Nitrophenylacetic acid is a white crystalline solid with no distinct odor. It appears as needle-like crystals in its pure form.
The molar mass of 4-Nitrophenylacetic acid is approximately 181.15 g/mol, with a density of about 1.45 g/cm³. This places it in line with common food items in terms of molar mass and density, such as sugar or salt.
The melting point of 4-Nitrophenylacetic acid is around 160-165°C, while the boiling point is approximately 370-380°C. These values are much higher than those of common food items, such as butter or chocolate.
4-Nitrophenylacetic acid is slightly soluble in water and has a low viscosity. Its solubility in water is comparable to that of substances like baking soda, while its viscosity is similar to that of vinegar.
🏭 Production & Procurement
4-Nitrophenylacetic acid is typically produced through the nitration of phenylacetic acid using a combination of nitric and sulfuric acids. This chemical reaction results in the substitution of a nitro group at the para position of the phenylacetic acid molecule, leading to the formation of 4-Nitrophenylacetic acid.
After production, 4-Nitrophenylacetic acid can be procured from chemical suppliers or manufacturers who specialize in providing various organic compounds. The compound is usually transported in sealed containers or drums to prevent contamination or degradation during transit. Specialized shipping and handling procedures may be required due to the compound’s potentially reactive nature.
When procuring 4-Nitrophenylacetic acid, it is important to ensure that the compound meets the necessary purity and quality standards for its intended use. Buyers should verify the supplier’s certifications and quality control measures to guarantee the compound’s integrity. Proper storage and handling practices must also be followed to maintain the compound’s stability and prevent any potential hazards during transportation and storage.
⚠️ Safety Considerations
Safety considerations for handling 4-Nitrophenylacetic acid should not be taken lightly due to its potential health hazards. It is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat when working with this compound to prevent skin and eye irritation. Additionally, it is essential to work in a well-ventilated area to avoid inhaling any fumes or vapors that may be released during handling.
Hazard statements for 4-Nitrophenylacetic acid include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements highlight the potential dangers associated with this compound and emphasize the importance of taking necessary precautions when working with it. It is crucial to handle 4-Nitrophenylacetic acid with care and to avoid any direct contact with skin, eyes, or respiratory system.
Precautionary statements for 4-Nitrophenylacetic acid include “Wear protective gloves/eye protection/face protection,” “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing,” and “IF INHALED: Remove person to fresh air and keep comfortable for breathing.” These statements outline the specific actions to take in case of exposure to 4-Nitrophenylacetic acid and stress the importance of following proper safety procedures to minimize the risk of harm. Proper handling and storage of this compound are essential to ensure the safety of laboratory personnel.
🔬 Potential Research Directions
One potential research direction for 4-Nitrophenylacetic acid is its use in the development of novel pharmaceutical compounds. Researchers may investigate the compound’s pharmacological properties and its potential as a therapeutic agent for various medical conditions.
Another area of interest could be the study of 4-Nitrophenylacetic acid’s environmental impact. Research could focus on its biodegradability, toxicity, and potential for bioaccumulation in different ecosystems. This information could be valuable for assessing the compound’s environmental risk and developing strategies for its safe disposal.
Furthermore, studies may explore the chemical reactivity of 4-Nitrophenylacetic acid, including its potential for forming derivatives or undergoing reactions with other compounds. Understanding its reaction mechanisms and kinetics could provide insights for synthetic chemists aiming to design new molecules based on this compound.
Additionally, investigations into the crystal structure and physical properties of 4-Nitrophenylacetic acid could contribute to the development of materials science applications. By elucidating its solid-state properties, researchers may discover new ways to incorporate the compound into functional materials for various industrial purposes.
🧪 Related Compounds
One similar compound to 4-Nitrophenylacetic acid is 4-Nitrobenzoic acid. This compound has a similar molecular structure, but with a benzoic acid group instead of an acetic acid group. The presence of the nitro group in both compounds imparts similar chemical properties, such as increased acidity and electron-withdrawing effects.
Another similar compound is 4-Nitrophenol. This compound also contains a nitro group attached to a phenolic ring, but in this case, there is no carboxylic acid group. Despite this structural difference, 4-Nitrophenol shares some physical and chemical properties with 4-Nitrophenylacetic acid due to the presence of the nitro group on the aromatic ring.
4-Nitroaniline is yet another compound similar to 4-Nitrophenylacetic acid. This compound contains a nitro group attached to an aniline ring, rather than a phenolic or carboxylic acid group. Despite this structural variation, 4-Nitroaniline shares some chemical reactivity and aromatic properties with 4-Nitrophenylacetic acid due to the presence of the nitro group.
