4-Methoxyphenethylamine, more commonly known as 4-MeO-PEA, is a compound that holds significance in various fields such as chemistry, neuroscience, and pharmacology. This organic compound has stimulant properties that can affect neurotransmitter activity in the brain. Although not widely recognized in everyday life, research on 4-MeO-PEA’s potential therapeutic applications and its influence on brain function could have implications for the development of new medications for treating conditions such as depression, anxiety, and other mental health disorders. Its relevance lies in its potential to inform advancements in the field of neuroscience and pharmaceuticals, impacting individuals’ well-being and quality of life in the future.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
4-Methoxyphenethylamine, also known as 4-MeO-PEA, is primarily used in commercial and industrial applications as a precursor in the synthesis of various compounds. It has been utilized in the production of organic chemicals, pharmaceuticals, and research chemicals. Additionally, this compound has found applications in the manufacturing of fragrances and flavoring agents, due to its aromatic properties.
In terms of drug and medication applications, 4-Methoxyphenethylamine has been studied for its potential as a psychoactive substance. It is structurally related to phenethylamine, a class of compounds known for their stimulant and hallucinogenic effects. Studies have shown that 4-MeO-PEA interacts with serotonin receptors in the brain, leading to alterations in mood and perception.
Research into the pharmacological properties of 4-Methoxyphenethylamine has indicated that it may have therapeutic potential in the treatment of certain mental health disorders. Some studies have suggested that this compound could be used as a novel antidepressant or anxiolytic agent. However, further research is needed to fully understand its effects and safety profile before any clinical applications can be realized.
⚗️ Chemical & Physical Properties
4-Methoxyphenethylamine is a crystalline solid that appears as white to off-white powders. It has a slight amine odor.
The molar mass of 4-Methoxyphenethylamine is approximately 151.21 g/mol, with a density of about 1.09 g/cm³. Compared to common food items such as sugar (molar mass ≈ 342.3 g/mol, density ≈ 1.59 g/cm³) and salt (molar mass ≈ 58.44 g/mol, density ≈ 2.16 g/cm³), 4-Methoxyphenethylamine has a lower molar mass and density.
4-Methoxyphenethylamine has a melting point of around 33-35°C and a boiling point of approximately 200-210°C. Compared to common food items like butter (melting point ≈ 32-35°C, boiling point ≈ 350°C) and olive oil (melting point ≈ -6°C, boiling point ≈ 180-240°C), 4-Methoxyphenethylamine has similar melting and boiling points.
This compound is sparingly soluble in water with a low viscosity. In comparison to common food items like sugar (high solubility in water, low viscosity) and vegetable oil (insoluble in water, higher viscosity), 4-Methoxyphenethylamine exhibits different solubility and viscosity properties.
🏭 Production & Procurement
4-Methoxyphenethylamine, also known as 4-Methoxy-B-phenethylamine or 4-MeO-PEA, is a psychoactive compound and a substituted phenethylamine. It is produced through chemical synthesis by reacting 4-methoxybenzaldehyde with nitroethane in the presence of a reducing agent such as ammonium formate, followed by reduction of the nitro group to yield 4-Methoxyphenethylamine.
The procurement of 4-Methoxyphenethylamine typically involves ordering the compound from chemical suppliers specializing in research chemicals. Due to its psychoactive properties, its handling and transportation are subject to strict regulations, including proper labeling and documentation. The compound is usually shipped in a solid form, either as a powder or crystals, and must be handled with care to prevent contamination or degradation during transit.
Once procured, 4-Methoxyphenethylamine can be transported in sealed, labeled containers to ensure its integrity and prevent exposure during transit. Proper storage conditions, such as cool, dry environments away from direct sunlight, must be maintained to preserve the compound’s stability. Regulatory compliance with local laws governing the transportation of psychoactive substances is essential to avoid legal repercussions.
⚠️ Safety Considerations
Safety considerations for 4-Methoxyphenethylamine, also known as 4-MeO-PEA, include its potential hazards as a psychoactive substance. It is important to note that 4-Methoxyphenethylamine is not approved for human consumption and is considered a research chemical. Due to its stimulant properties, there is a risk of overdose, which can result in serious health effects, including cardiac arrest, seizures, and even death. Additionally, the purity and dosage of 4-Methoxyphenethylamine can vary significantly between sources, increasing the risk of adverse reactions and unexpected side effects.
Furthermore, it is crucial to handle 4-Methoxyphenethylamine with care and caution due to its potential for misuse and abuse. Individuals who choose to experiment with this substance should be aware of the legal implications and health risks associated with its consumption. Proper storage and handling of 4-Methoxyphenethylamine are essential to prevent accidental exposure and minimize the risk of harm. It is strongly recommended to only obtain 4-Methoxyphenethylamine from reputable sources and to educate oneself on its potential effects and risks before use.
The hazard statements associated with 4-Methoxyphenethylamine include its classification as a dangerous substance that can cause harm to human health. It is important to be aware of the potential risks and hazards associated with handling and consuming this compound. Some key hazard statements for 4-Methoxyphenethylamine include: “May be harmful if swallowed, inhaled, or absorbed through the skin”, “May cause respiratory irritation”, and “May cause dizziness or drowsiness.” These statements serve as a warning to individuals about the potential dangers of exposure to 4-Methoxyphenethylamine and emphasize the need for caution when handling this substance.
Precautionary statements for 4-Methoxyphenethylamine provide guidance on the safe handling, storage, and disposal of this compound to minimize the risk of harm to individuals and the environment. It is important to follow these precautionary statements to ensure the proper management of 4-Methoxyphenethylamine and to prevent accidents or adverse effects. Some key precautionary statements for 4-Methoxyphenethylamine include: “Keep out of reach of children”, “Avoid breathing dust/fume/gas/mist/vapors/spray”, “Wear protective gloves/protective clothing/eye protection/face protection”, “Dispose of contents/container in accordance with local/regional/national/international regulations.” These statements are designed to promote safe practices when working with 4-Methoxyphenethylamine and to reduce the risk of harm to individuals and the environment.
🔬 Potential Research Directions
Research on 4-Methoxyphenethylamine may focus on its potential therapeutic applications, exploring its effects on neurotransmitter systems and its potential as a treatment for various psychological disorders. Studies may investigate the compound’s pharmacological profile, including its affinity for receptors in the brain and its potential side effects.
Further research directions could include exploring the metabolism of 4-Methoxyphenethylamine in the body, elucidating the pathways by which the compound is broken down and excreted. This information could be valuable in understanding the compound’s pharmacokinetics and in optimizing dosing regimens for potential clinical use.
Additionally, studies may investigate the structure-activity relationships of 4-Methoxyphenethylamine and its analogs, with the goal of developing more potent or selective compounds with improved therapeutic profiles. This research could lead to the discovery of novel drug candidates for the treatment of various neurological or psychiatric conditions.
Finally, research on 4-Methoxyphenethylamine could explore its interactions with other drugs or substances, including potential drug-drug interactions and its abuse liability. Understanding how the compound interacts with other compounds could be critical in assessing its safety and efficacy in clinical settings.
🧪 Related Compounds
One similar compound to 4-Methoxyphenethylamine based upon molecular structure is 3-Methoxyphenethylamine. This compound differs from 4-Methoxyphenethylamine by having the methoxy group located on the third carbon of the phenethylamine backbone instead of the fourth carbon. Despite this difference, both compounds share similar chemical properties due to the presence of the methoxy group.
Another similar compound is 2-Methoxyphenethylamine. In this compound, the methoxy group is located on the second carbon of the phenethylamine backbone, further altering the chemical properties compared to 4-Methoxyphenethylamine. However, the presence of the methoxy group still contributes to similarities in their chemical behavior.
Additionally, 4-Ethoxyphenethylamine is another compound with a similar molecular structure to 4-Methoxyphenethylamine. In this compound, the methoxy group is replaced with an ethoxy group, resulting in a different substituent on the phenethylamine backbone. Despite this difference, both compounds may exhibit similar chemical reactivity and properties due to the presence of the ethoxy group.
